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    CXCL5 C-X-C motif chemokine ligand 5 [ Homo sapiens (human) ]

    Gene ID: 6374, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CXCL5 impedes CD8[+] T cell immunity by upregulating PD-L1 expression in lung cancer via PXN/AKT signaling phosphorylation and neutrophil chemotaxis.

    CXCL5 impedes CD8(+) T cell immunity by upregulating PD-L1 expression in lung cancer via PXN/AKT signaling phosphorylation and neutrophil chemotaxis.
    Sun D, Tan L, Chen Y, Yuan Q, Jiang K, Liu Y, Xue Y, Zhang J, Cao X, Xu M, Luo Y, Xu Z, Xu Z, Xu W, Shen M., Free PMC Article

    07/23/2024
    A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis.

    A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis.
    Lei Q, Zhen S, Zhang L, Zhao Q, Yang L, Zhang Y., Free PMC Article

    05/6/2024
    CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis.

    CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis.
    Yin C, Liu B, Dong Z, Shi S, Peng C, Pan Y, Bi X, Nie H, Zhang Y, Tai Y, Hu Q, Wang X, Shao X, An H, Fang J, Wang C, Liu B., Free PMC Article

    04/22/2024
    Serum levels of CXCL5 are decreased and correlate with circulating platelet counts in systemic lupus erythematosus.

    Serum levels of CXCL5 are decreased and correlate with circulating platelet counts in systemic lupus erythematosus.
    Zhang L, Zhao L, Du K, Chen J, Ding H, Petersen F, Ye S, Lin Z, Yu X.

    03/6/2024
    Prognostic marker CXCL5 in glioblastoma polyformis and its mechanism of immune invasion.

    Prognostic marker CXCL5 in glioblastoma polyformis and its mechanism of immune invasion.
    Yu W, Zhou M, Niu H, Li J, Li Q, Xu X, Liang F, Rui C., Free PMC Article

    02/8/2024
    CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1.

    CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1.
    Cao X, Fang H, Zhou L.

    02/6/2024
    CXCL5 and CXCL14, but not CXCL16 as potential biomarkers of colorectal cancer.

    CXCL5 and CXCL14, but not CXCL16 as potential biomarkers of colorectal cancer.
    Zajkowska M, Dulewicz M, Kulczyńska-Przybik A, Safiejko K, Juchimiuk M, Konopko M, Kozłowski L, Mroczko B., Free PMC Article

    11/1/2023
    DIA-based analysis of the menstrual blood proteome identifies association between CXCL5 and IL1RN and endometriosis.

    DIA-based analysis of the menstrual blood proteome identifies association between CXCL5 and IL1RN and endometriosis.
    Ji S, Liu Y, Yan L, Zhang Y, Li Y, Zhu Q, Xia W, Ge S, Zhang J.

    11/1/2023
    CXCL5 promotes tumorigenesis and angiogenesis of glioblastoma via JAK-STAT/NF-kappab signaling pathways.

    CXCL5 promotes tumorigenesis and angiogenesis of glioblastoma via JAK-STAT/NF-κb signaling pathways.
    Mao P, Wang T, Du CW, Yu X, Wang MD.

    10/24/2023
    Mechanistic role of CXCL5 in cardiovascular disease, diabetes mellitus, and kidney disease.

    Mechanistic role of CXCL5 in cardiovascular disease, diabetes mellitus, and kidney disease.
    Chen C, Chang TT, Chen JW.

    09/26/2023
    Plasma-Derived Small Extracellular Vesicles From VKH Patients Suppress T Cell Proliferation Via MicroRNA-410-3p Modulation of CXCL5 Axis.

    Plasma-Derived Small Extracellular Vesicles From VKH Patients Suppress T Cell Proliferation Via MicroRNA-410-3p Modulation of CXCL5 Axis.
    Li B, Sun N, Yang F, Guo K, Wu L, Ma M, Shao H, Li X, Zhang X., Free PMC Article

    09/25/2023
    Is elevated ENA-78 serum level a link between obstructive sleep apnea and atherosclerosis?

    Is elevated ENA-78 serum level a link between obstructive sleep apnea and atherosclerosis?
    Nahorecki A, Szuba A, Martynowicz H, Szponder M, Janczak D, Postrzech-Adamczyk K.

    06/30/2023
    Collagen-induced DDR1 upregulates CXCL5 to promote neutrophil extracellular traps formation and Treg infiltration in breast cancer.

    Collagen-induced DDR1 upregulates CXCL5 to promote neutrophil extracellular traps formation and Treg infiltration in breast cancer.
    Li H, Li J, Bai Z, Yan S, Li J.

    06/19/2023
    Renal clear cell carcinoma-derived CXCL5 drives tumor-associated fibroblast formation and facilitates cancer progression.

    Renal clear cell carcinoma-derived CXCL5 drives tumor-associated fibroblast formation and facilitates cancer progression.
    Liu Y, Qu HC, Huang Y.

    04/12/2023
    Serum CXCL5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression.

    Serum CXCL5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression.
    Laschtowitz A, Lambrecht J, Puengel T, Tacke F, Mohr R., Free PMC Article

    03/30/2023
    Targeting CXCL5 in Pancreatic Cancer Cells Inhibits Cancer Xenograft Growth by Reducing Proliferation and Inhibiting EMT Progression.

    Targeting CXCL5 in Pancreatic Cancer Cells Inhibits Cancer Xenograft Growth by Reducing Proliferation and Inhibiting EMT Progression.
    Wang ZZ, Li XT, Li QJ, Zhou JX.

    03/16/2023
    IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury.

    IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury.
    Xiao G, Kumar R, Komuro Y, Burguet J, Kakarla V, Azizkhanian I, Sheth SA, Williams CK, Zhang XR, Macknicki M, Brumm A, Kawaguchi R, Mai P, Kaneko N, Vinters HV, Carmichael ST, Havton LA, DeCarli C, Hinman JD., Free PMC Article

    01/14/2023
    ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model.

    ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model.
    Wang YY, Hung AC, Wu YC, Lo S, Chen HD, Chen YK, Hsieh YC, Hu SC, Hou MF, Yuan SF., Free PMC Article

    10/1/2022
    miR-145-3p Hampers the Malignant Progression of Esophageal Carcinoma via CXCL5 Downregulation.

    miR-145-3p Hampers the Malignant Progression of Esophageal Carcinoma via CXCL5 Downregulation.
    Chen G, Teng Z, Zhu Z, Li X., Free PMC Article

    08/13/2022
    MicroRNA-873-5p suppresses cell malignant behaviors of thyroid cancer via targeting CXCL5 and regulating P53 pathway.

    MicroRNA-873-5p suppresses cell malignant behaviors of thyroid cancer via targeting CXCL5 and regulating P53 pathway.
    Chang W, Chang Q, Lu H, Liu S, Li Y, Chen C., Free PMC Article

    07/30/2022
    Sox9/CXCL5 axis facilitates tumour cell growth and invasion in hepatocellular carcinoma.

    Sox9/CXCL5 axis facilitates tumour cell growth and invasion in hepatocellular carcinoma.
    Ren Z, Chen Y, Shi L, Shao F, Sun Y, Ge J, Zhang J, Zang Y.

    06/25/2022
    [CXCL5 inhibits tumor immune of lung cancer via modulating PD1/PD-L1 signaling].

    [CXCL5 inhibits tumor immune of lung cancer via modulating PD1/PD-L1 signaling].
    Xie XH, Wang YJ, Lei W, Gao HJ, Duan YJ, Hou X.

    06/18/2022
    KIF4A promotes tumor progression of bladder cancer via CXCL5 dependent myeloid-derived suppressor cells recruitment.

    KIF4A promotes tumor progression of bladder cancer via CXCL5 dependent myeloid-derived suppressor cells recruitment.
    Lin N, Chen L, Zhang Y, Yang Y, Zhang L, Chen L, Zhang P, Su H, Yin M., Free PMC Article

    04/23/2022
    EMT-mediated regulation of CXCL1/5 for resistance to anti-EGFR therapy in colorectal cancer.

    EMT-mediated regulation of CXCL1/5 for resistance to anti-EGFR therapy in colorectal cancer.
    Park YL, Kim HP, Ock CY, Min DW, Kang JK, Lim YJ, Song SH, Han SW, Kim TY.

    04/9/2022
    Inhibition of Autophagy Does Not Affect Innate Cytokine Production in Human Lung Epithelial Cells During Respiratory Syncytial Virus Infection.

    Inhibition of Autophagy Does Not Affect Innate Cytokine Production in Human Lung Epithelial Cells During Respiratory Syncytial Virus Infection.
    Azman AF, Chia SL, Sekawi Z, Yusoff K, Ismail S.

    03/12/2022
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