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    CXCL11 C-X-C motif chemokine ligand 11 [ Homo sapiens (human) ]

    Gene ID: 6373, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Stem-like signatures in human meningioma cells are under the control of CXCL11/CXCL12 chemokine activity.

    Stem-like signatures in human meningioma cells are under the control of CXCL11/CXCL12 chemokine activity.
    Barbieri F, Bajetto A, Dellacasagrande I, Solari A, Würth R, Fernandez V, Rancati S, Ceresa D, Appolloni I, De Luca G, Dono M, Nozza P, Schiapparelli P, Gambaro M, Fiaschi P, Gaggero G, Costanzo N, Thellung S, Malatesta P, Pagano A, Zona G, De Pietri Tonelli D, Florio T., Free PMC Article

    10/5/2023
    Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells.

    Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells.
    Koch C, Fischer NC, Puchert M, Engele J., Free PMC Article

    12/31/2022
    The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.

    The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.
    Liu G, Yang ZF, Sun J, Sun BY, Zhou PY, Zhou C, Guan RY, Wang ZT, Yi Y, Qiu SJ., Free PMC Article

    12/24/2022
    CXCL11 Correlates with Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis.

    CXCL11 Correlates with Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis.
    Li Y, Han S, Wu B, Zhong C, Shi Y, Lv C, Fu L, Zhang Y, Lang Q, Liang Z, Yu Y, Tian Y., Free PMC Article

    08/13/2022
    RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B.

    RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B.
    Li L, Gan YP, Peng H.

    05/21/2022
    Epigenetic activation of RBM15 promotes clear cell renal cell carcinoma growth, metastasis and macrophage infiltration by regulating the m6A modification of CXCL11.

    Epigenetic activation of RBM15 promotes clear cell renal cell carcinoma growth, metastasis and macrophage infiltration by regulating the m6A modification of CXCL11.
    Zeng X, Chen K, Li L, Tian J, Ruan W, Hu Z, Peng D, Chen Z.

    05/21/2022
    Colon cancer cells secreted CXCL11 via RBP-Jkappa to facilitated tumour-associated macrophage-induced cancer metastasis.

    Colon cancer cells secreted CXCL11 via RBP-Jκ to facilitated tumour-associated macrophage-induced cancer metastasis.
    Liu M, Fu X, Jiang L, Ma J, Zheng X, Wang S, Guo H, Tian T, Nan K, Wang W., Free PMC Article

    03/19/2022
    Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.

    Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.
    Moreno B, Hueso L, Ortega R, Benito E, Martínez-Hervas S, Peiro M, Civera M, Sanz MJ, Piqueras L, Real JT.

    03/12/2022
    Mechanisms underlying the production of chemokine CXCL11 in the reaction of renal tubular epithelial cells with CD4(+) and CD8(+) T cells.

    Mechanisms underlying the production of chemokine CXCL11 in the reaction of renal tubular epithelial cells with CD4(+) and CD8(+) T cells.
    Wang X, Wang D, Wang X, Wang X, Sha JC, Gao Q.

    01/22/2022
    Childhood CCL18, CXCL10 and CXCL11 levels differentially relate to and predict allergy development.

    Childhood CCL18, CXCL10 and CXCL11 levels differentially relate to and predict allergy development.
    Huoman J, Haider S, Simpson A, Murray CS, Custovic A, Jenmalm MC.

    01/15/2022
    Identification of CXCL11 as part of chemokine network controlling skeletal muscle development.

    Identification of CXCL11 as part of chemokine network controlling skeletal muscle development.
    Puchert M, Koch C, Zieger K, Engele J., Free PMC Article

    11/27/2021
    Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis.

    Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis.
    Liu G, Sun J, Yang ZF, Zhou C, Zhou PY, Guan RY, Sun BY, Wang ZT, Zhou J, Fan J, Qiu SJ, Yi Y., Free PMC Article

    09/18/2021
    The intratumoral CXCR3 chemokine system is predictive of chemotherapy response in human bladder cancer.

    The intratumoral CXCR3 chemokine system is predictive of chemotherapy response in human bladder cancer.
    Vollmer T, Schlickeiser S, Amini L, Schulenberg S, Wendering DJ, Banday V, Jurisch A, Noster R, Kunkel D, Brindle NR, Savidis I, Akyüz L, Hecht J, Stervbo U, Roch T, Babel N, Reinke P, Winqvist O, Sherif A, Volk HD, Schmueck-Henneresse M.

    07/24/2021
    The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner.

    The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner.
    Callahan V, Hawks S, Crawford MA, Lehman CW, Morrison HA, Ivester HM, Akhrymuk I, Boghdeh N, Flor R, Finkielstein CV, Allen IC, Weger-Lucarelli J, Duggal N, Hughes MA, Kehn-Hall K., Free PMC Article

    07/17/2021
    CXCL11 promotes tumor progression by the biased use of the chemokine receptors CXCR3 and CXCR7.

    CXCL11 promotes tumor progression by the biased use of the chemokine receptors CXCR3 and CXCR7.
    Puchert M, Obst J, Koch C, Zieger K, Engele J.

    05/15/2021
    The CXCL11-CXCR3A axis influences the infiltration of CD274 and IDO1 in oral squamous cell carcinoma.

    The CXCL11-CXCR3A axis influences the infiltration of CD274 and IDO1 in oral squamous cell carcinoma.
    Wang X, Zhang J, Zhou G.

    04/24/2021
    Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells.

    Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells.
    Hwang HJ, Lee YR, Kang D, Lee HC, Seo HR, Ryu JK, Kim YN, Ko YG, Park HJ, Lee JS.

    01/23/2021
    The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression.

    The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression.
    Yin X, Wang Z, Wu T, Ma M, Zhang Z, Chu Z, Hu Q, Ding H, Han X, Xu J, Shang H, Jiang Y., Free PMC Article

    09/12/2020
    serum CXCL11 and CXCL12 levels were elevated in cirrhotic patients

    Circulating levels of CXCL11 and CXCL12 are biomarkers of cirrhosis in patients with chronic hepatitis C infection.
    Chalin A, Lefevre B, Devisme C, Barget N, Amiot L, Samson M.

    07/4/2020
    Study confirmed that CXCL11 expression was significantly upregulated in hepatocellular carcinoma (HCC) alpha2delta1+ tumor-initiating cells (TICs) and that it played a crucial role in the acquirement and subsequent maintenance of self-renewal and tumorigenic abilities of HCC alpha2delta1+ TICs through the CXCR3/ERK1/2 signaling axis via autocrine signaling.

    CXCL11 promotes self-renewal and tumorigenicity of α2δ1(+) liver tumor-initiating cells through CXCR3/ERK1/2 signaling.
    Zhang Y, Zhao W, Li S, Lv M, Yang X, Li M, Zhang Z.

    01/25/2020
    These findings identify a feed-forward mechanism that sustains activation of the CXCR7/CXCL11 axis under ERalpha control to induce the epithelial-mesenchymal transition pathway and metastatic behavior of ovarian cancer cells.

    Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer.
    Benhadjeba S, Edjekouane L, Sauvé K, Carmona E, Tremblay A., Free PMC Article

    08/10/2019
    Studied role of chemokines (including C-X-C motif chemokine ligand 11 [CXCL11] and C-X-C motif chemokine ligand 10 [CXCL10] in the CXCR3 axis with regards to angiogenesis in adipose tissue of morbidly obese patients.

    Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis.
    Hueso L, Ortega R, Selles F, Wu-Xiong NY, Ortega J, Civera M, Ascaso JF, Sanz MJ, Real JT, Piqueras L.

    06/29/2019
    Finding demonstrated that miR-206 negatively regulated PCa cell proliferation and migration, and arrested cell cycle by targeting CXCL11 as a tumor suppressor in prostate cancer.

    MiR-206 inhibits proliferation and migration of prostate cancer cells by targeting CXCL11.
    Wang Y, Xu H, Si L, Li Q, Zhu X, Yu T, Gang X.

    03/16/2019
    V2O5 induction of CXCL8 and CXCL11 chemokines may lead to the appearance and perpetuation of an inflammatory reaction into the dermal tissue. Further studies are required to evaluate dermal integrity and manifestations in subjects occupationally exposed, or living in polluted areas.

    CXCL8 and CXCL11 chemokine secretion in dermal fibroblasts is differentially modulated by vanadium pentoxide.
    Fallahi P, Foddis R, Elia G, Ragusa F, Patrizio A, Benvenga S, Cristaudo A, Antonelli A, Ferrari SM.

    10/20/2018
    BK polyomavirus infection can induce CXCL11 gene expression in kidney transplant patients.

    Association of BK Virus Infection with CXCL11 Gene Expression and Protein Levels in Kidney Transplant Patients.
    Kariminik A, Yaghobi R, Dabiri S.

    09/22/2018
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