Biallelic Loss-of-Function Variants in BICD1 Are Associated with Peripheral Neuropathy and Hearing Loss. | Biallelic Loss-of-Function Variants in BICD1 Are Associated with Peripheral Neuropathy and Hearing Loss. Hirsch Y, Chung WK, Novoselov S, Weimer LH, Rossor A, LeDuc CA, McPartland AJ, Cabrera E, Ekstein J, Scher S, Nelson RF, Schiavo G, Henderson LB, Booth KTA., Free PMC Article | 08/23/2023 |
BICD1 functions as a prognostic biomarker and promotes hepatocellular carcinoma progression. | BICD1 functions as a prognostic biomarker and promotes hepatocellular carcinoma progression. Jiang Y, Yao B, Chen T, Mo H, Chen S, Liu Q, Sun Y. | 01/23/2021 |
BICD1 mediates HIF1alpha nuclear translocation in mesenchymal stem cells during hypoxia adaptation. | BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation. Lee HJ, Jung YH, Oh JY, Choi GE, Chae CW, Kim JS, Lim JR, Kim SY, Lee SJ, Seong JK, Han HJ., Free PMC Article | 09/5/2020 |
The disrupting Bicd1/Fignl1 interaction induced motor axon pathfinding defects characteristic of Fignl1 gain or loss of function, respectively. | FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation. Atkins M, Gasmi L, Bercier V, Revenu C, Del Bene F, Hazan J, Fassier C., Free PMC Article | 05/16/2020 |
BICD1 genes may contribute to the decrease in forced vital capacity levels by interacting with PM10 exposure | A genome-wide by PM(10) interaction study identifies novel loci for lung function near BICD1 and IL1RN-IL1F10 genes in Korean adults. Kim HJ, Seo YS, Sung J, Chae J, Yun JM, Kwon H, Cho B, Kim JI, Park JH. | 04/11/2020 |
Data suggest that BICD1 and BICD2 are highly expressed in the nervous system during development and are important in neuronal homeostasis. [REVIEW] | Neuronal Roles of the Bicaudal D Family of Motor Adaptors. Budzinska M, Wicher KB, Terenzio M. | 11/4/2017 |
This study showed that rs2735940 hTERT CX-TT donor-recipient genotype pair was associated with almost five times higher odds (OR=4.82; 95% CI: 1.32-18; p=0.016) of delayed graft function (DGF), and that rs2735940 hTERT, rs2630578 BICD1, and rs7235755 chromosome 18 polymorphisms combined pairs were not associated with acute rejection (AR). | Joint Assessment of Donor and Recipient hTERT Gene Polymorphism Provides Additional Information for Early Kidney Transplantation Outcomes. Kłoda K, Mierzecki A, Domański L, Borowiecka E, Safranow K, Ciechanowicz A, Ciechanowski K., Free PMC Article | 06/24/2017 |
Kidney transplant recipients' polymorphisms of genes associated with telomere length, BICD1 and chromosome 18, but not hTERT, affect kidney allograft early and long-term function after transplantation. | BICD1 and Chromosome 18 Polymorphisms Associated With Recipients' Telomere Length Affect Kidney Allograft Function After Transplantation. Kłoda K, Domański L, Kwiatkowska E, Safranow K, Drozd A, Ciechanowicz A, Ciechanowski K. | 04/22/2017 |
Graft BICD1 polymorphisms apart from the association with telomere length, affect early kidney function after transplantation | hTERT, BICD1 and chromosome 18 polymorphisms associated with telomere length affect kidney allograft function after transplantation. Kłoda K, Domanski L, Kwiatkowska E, Borowiecka E, Safranow K, Drozd A, Ciechanowicz A, Maciejewska-Karłowska A, Sawczuk M, Pawlik A, Ciechanowski K. | 12/19/2015 |
Variants in BICD1 are associated with length of telomeres, which suggests that a mechanism linked to accelerated aging may be involved in the pathogenesis of emphysema. | Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Kong X, Cho MH, Anderson W, Coxson HO, Muller N, Washko G, Hoffman EA, Bakke P, Gulsvik A, Lomas DA, Silverman EK, Pillai SG, ECLIPSE Study NETT Investigators, Kong X, Cho MH, Anderson W, Coxson HO, Muller N, Washko G, Hoffman EA, Bakke P, Gulsvik A, Lomas DA, Silverman EK, Pillai SG, ECLIPSE Study NETT Investigators., Free PMC Articles: PMC3040393, PMC3040393 | 03/26/2011 |
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Kong X, Cho MH, Anderson W, Coxson HO, Muller N, Washko G, Hoffman EA, Bakke P, Gulsvik A, Lomas DA, Silverman EK, Pillai SG, ECLIPSE Study NETT Investigators, Kong X, Cho MH, Anderson W, Coxson HO, Muller N, Washko G, Hoffman EA, Bakke P, Gulsvik A, Lomas DA, Silverman EK, Pillai SG, ECLIPSE Study NETT Investigators. Genome-wide association study of pancreatic cancer in Japanese population. Low SK, Kuchiba A, Zembutsu H, Saito A, Takahashi A, Kubo M, Daigo Y, Kamatani N, Chiku S, Totsuka H, Ohnami S, Hirose H, Shimada K, Okusaka T, Yoshida T, Nakamura Y, Sakamoto H. | 09/15/2010 |
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
the protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization | A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization. Swift S, Xu J, Trivedi V, Austin KM, Tressel SL, Zhang L, Covic L, Kuliopulos A., Free PMC Article | 05/10/2010 |
Observational study of gene-disease association. (HuGE Navigator) | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. Xu J, Zheng SL, Isaacs SD, Wiley KE, Wiklund F, Sun J, Kader AK, Li G, Purcell LD, Kim ST, Hsu FC, Stattin P, Hugosson J, Adolfsson J, Walsh PC, Trent JM, Duggan D, Carpten J, Grönberg H, Isaacs WB., Free PMC Article | 04/7/2010 |
BICD1 plays a similar role in telomere length homeostasis in humans. | A regulatory SNP of the BICD1 gene contributes to telomere length variation in humans. Mangino M, Brouilette S, Braund P, Tirmizi N, Vasa-Nicotera M, Thompson JR, Samani NJ. | 01/21/2010 |
The brain-specific Rab6B via Bicaudal-D1 is linked to the dynein/dynactin complex, suggesting a regulatory role for Rab6B in the retrograde transport of cargo in neuronal cells. | A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells. Wanschers BF, van de Vorstenbosch R, Schlager MA, Splinter D, Akhmanova A, Hoogenraad CC, Wieringa B, Fransen JA. | 01/21/2010 |
These results imply that GSK-3beta may function in transporting centrosomal proteins to the centrosome by stabilizing the BICD1 and dynein complex, resulting in the regulation of a focused microtubule organization. | GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome. Fumoto K, Hoogenraad CC, Kikuchi A., Free PMC Article | 01/21/2010 |
Various processes in which BicD is involved during Drosophilian development (review) | BicD-dependent localization processes: from Drosophilia development to human cell biology. Claussen M, Suter B. | 01/21/2010 |
findings show BICD1 localized to Chlamydia trachomatis inclusions in a biovar-specific manner and that EGFP-BICD1 is recruited to the inclusion in a microtubule- and Golgi apparatus-independent but chlamydial gene expression-dependent mechanism | The Rab6 effector Bicaudal D1 associates with Chlamydia trachomatis inclusions in a biovar-specific manner. Moorhead AR, Rzomp KA, Scidmore MA., Free PMC Article | 01/21/2010 |