| CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity. | CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity.
Kim ES, Nam SM, Song HK, Lee S, Kim K, Lim HK, Lee H, Kang KT, Kwon YJ, Chun YJ, Park SY, Jung J, Moon A. | 08/7/2024 |
| CCL2, CCL8, CXCL12 chemokines in resectable non-small cell lung cancer (NSCLC). | CCL2, CCL8, CXCL12 chemokines in resectable non-small cell lung cancer (NSCLC).
Drosslerova M, Sterclova M, Taskova A, Hytych V, Richterova E, Bruzova M, Spunda M, Komarc M, Koziar Vasakova M. | 12/18/2023 |
| CCL8 as a promising prognostic factor in diffuse large B-cell lymphoma via M2 macrophage interactions: A bioinformatic analysis of the tumor microenvironment. | CCL8 as a promising prognostic factor in diffuse large B-cell lymphoma via M2 macrophage interactions: A bioinformatic analysis of the tumor microenvironment.
Lou X, Zhao K, Xu J, Shuai L, Niu H, Cao Z, Wang J, Zhang Y., Free PMC Article | 09/17/2022 |
| PERK signaling through C/EBPdelta contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells. | PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells.
Sheshadri N, Poria DK, Sharan S, Hu Y, Yan C, Koparde VN, Balamurugan K, Sterneck E., Free PMC Article | 02/5/2022 |
| Possible involvement of crosstalk between endometrial cells and mast cells in the development of endometriosis via CCL8/CCR1. | Possible involvement of crosstalk between endometrial cells and mast cells in the development of endometriosis via CCL8/CCR1.
Li T, Wang J, Guo X, Yu Q, Ding S, Xu X, Peng Y, Zhu L, Zou G, Zhang X. | 02/27/2021 |
| Silencing CCL8 inhibited the proliferation and migration of PDGF-BB-stimulated human aortic smooth muscle cells. | Silencing CCL8 inhibited the proliferation and migration of PDGF-BB-stimulated human aortic smooth muscle cells.
Dai S, Zhang J, Xu Z. | 02/13/2021 |
| CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling. | CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling.
Zhang X, Chen L, Dang WQ, Cao MF, Xiao JF, Lv SQ, Jiang WJ, Yao XH, Lu HM, Miao JY, Wang Y, Yu SC, Ping YF, Liu XD, Cui YH, Zhang X, Bian XW. | 10/24/2020 |
| Weighted gene correlation network analysis identifies RSAD2, HERC5, and CCL8 as prognostic candidates for breast cancer. | Weighted gene correlation network analysis identifies RSAD2, HERC5, and CCL8 as prognostic candidates for breast cancer.
Tang J, Yang Q, Cui Q, Zhang D, Kong D, Liao X, Ren J, Gong Y, Wu G. | 08/29/2020 |
| CCL18 promotes the invasion and metastasis of breast cancer through Annexin A2. | CCL18 promotes the invasion and metastasis of breast cancer through Annexin A2.
Zhao C, Zheng S, Yan Z, Deng Z, Wang R, Zhang B. | 08/22/2020 |
| The strongest associations with air pollution levels were observed among RANTES, TARC and MCP-2. Those chemokines may play important roles in the air pollution-induced inflammatory pathway. | Responses of serum chemokines to dramatic changes of air pollution levels, a panel study.
Li Y, Bonner MR, Browne RW, Deng F, Tian L, Jim Zhang J, Swanson M, Rittenhouse-Olson K, Farhat Z, Mu L., Free PMC Article | 02/15/2020 |
| MiR-345-5p was a tumor-suppressive miRNA in pancreatic cancer progression by targeting CCL8. | MiR-345-5p functions as a tumor suppressor in pancreatic cancer by directly targeting CCL8.
Mou T, Xie F, Zhong P, Hua H, Lai L, Yang Q, Wang J. | 06/22/2019 |
| It was shown that MCP2 was able to activate the NF-kappaB signaling pathway inducing the epithelial-mesenchymal transition (EMT) and promoting the migration and invasion of ESCC cells in vitro. | MCP2 activates NF-κB signaling pathway promoting the migration and invasion of ESCC cells.
Zhou J, Zheng S, Liu T, Liu Q, Chen Y, Tan D, Ma R, Lu X. | 08/18/2018 |
| Transcriptome analysis identified several novel IPF-related genes. Among them, CCL8 is a candidate molecule for the differential diagnosis and prediction of survival. | Gene profile of fibroblasts identify relation of CCL8 with idiopathic pulmonary fibrosis.
Lee JU, Cheong HS, Shim EY, Bae DJ, Chang HS, Uh ST, Kim YH, Park JS, Lee B, Shin HD, Park CS., Free PMC Article | 02/24/2018 |
| Findings exemplify how gradients of chemoattractive factors such as CCL8, drive metastasis and suggest that interference with their operation may provide means for breast cancer management. | A CCL8 gradient drives breast cancer cell dissemination.
Farmaki E, Chatzistamou I, Kaza V, Kiaris H., Free PMC Article | 09/16/2017 |
| Detecting expression changes in TLR4 and MCP2 in the peripheral blood is a feasible method for predicting the occurrence of abortion in women of child-bearing age | Relationship between TLR4 and MCP2 expression levels and habitual abortion.
Li XP, Song LN, Tian LP, Zhang YS. | 02/4/2017 |
| Dermal fibroblast CCL8 promotes melanoma metastasis. | The importance of microenvironment: the role of CCL8 in metastasis formation of melanoma.
Barbai T, Fejős Z, Puskas LG, Tímár J, Rásó E., Free PMC Article | 08/6/2016 |
| Authors show that the previously observed downregulation of hsa-miR-92a and upregulation of CCL8 during human cytomegalovirus latent infection of myeloid cells are intimately linked via the latency-associated expression of cytomegalovirus UL111A. | Latency-associated viral interleukin-10 (IL-10) encoded by human cytomegalovirus modulates cellular IL-10 and CCL8 Secretion during latent infection through changes in the cellular microRNA hsa-miR-92a.
Poole E, Avdic S, Hodkinson J, Jackson S, Wills M, Slobedman B, Sinclair J., Free PMC Article | 01/24/2015 |
| CCL8 is an antimicrobial protein with bacteriocidal activity against E. coli. | Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.
Yang D, Chen Q, Hoover DM, Staley P, Tucker KD, Lubkowski J, Oppenheim JJ. | 09/10/2014 |
| JAK2 and STAT3 activation is not essential for CCL3, CCL5 or CCL8 induced chemotaxis. | Janus kinase 2 and signal transducer and activator of transcription 3 activation is not essential for CCL3-, CCL5- or CCL8-induced chemotaxis.
Khabbazi S, Jacques RO, Moyano Cardaba C, Mueller A. | 10/26/2013 |
| Results indicate that the induction of MCP-2/CCL8 by mycobacteria is dependent on the activation of TLR2/PI3K/Akt signaling pathway. | Induction of CCL8/MCP-2 by mycobacteria through the activation of TLR2/PI3K/Akt signaling pathway.
Liu H, Liu Z, Chen J, Chen L, He X, Zheng R, Yang H, Song P, Weng D, Hu H, Fan L, Xiao H, Kaufmann SH, Ernst J, Ge B., Free PMC Article | 08/31/2013 |
| Macrophage Colony Stimulating Factor and Monocyte Chemoattractant Protein are elevated in sera of intrinsic asthmatics compared to normal controls. | Macrophage colony stimulating factor and monocyte chemoattractant protein 2 are elevated in intrinsic asthmatics.
Dajani R, Al-Haj Ali E, Dajani B. | 03/17/2012 |
| genetic polymorphhism is associated with a risk of death for non-small cell lung cancer in Chinese | Polymorphisms of key chemokine genes and survival of non-small cell lung cancer in Chinese.
Ma H, Shu Y, Pan S, Chen J, Dai J, Jin G, Hu Z, Shen H. | 02/11/2012 |
| Cytokine treatment increases mRNA stability only for chemokines CCL2 and CCL8 in airway epithelium, and transient silencing and overexpression of human antigen R affects only chemokine CCL2 and CCL8 expression in primary and transformed epithelial cells. | Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium.
Fan J, Ishmael FT, Fang X, Myers A, Cheadle C, Huang SK, Atasoy U, Gorospe M, Stellato C., Free PMC Article | 04/30/2011 |
| CCL8/MCP-2 is a target for mir-146a in HIV-1 infected microglia, as overexpression of mir-146a prevented HIV-induced secretion of MCP-2 chemokine | CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells.
Rom S, Rom I, Passiatore G, Pacifici M, Radhakrishnan S, Del Valle L, Piña-Oviedo S, Khalili K, Eletto D, Peruzzi F., Free PMC Article | 08/9/2010 |
| Observational study and meta-analysis of gene-disease association. (HuGE Navigator) | Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis.
Ockinger J, Stridh P, Beyeen AD, Lundmark F, Seddighzadeh M, Oturai A, Sørensen PS, Lorentzen AR, Celius EG, Leppä V, Koivisto K, Tienari PJ, Alfredsson L, Padyukov L, Hillert J, Kockum I, Jagodic M, Olsson T. | 12/2/2009 |