| ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. | ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression.
Chuang TP, Lai WY, Gabre JL, Lind DE, Umapathy G, Bokhari AA, Bergman B, Kristenson L, Thorén FB, Le A, Doebele RC, Van den Eynden J, Palmer RH, Hallberg B., Free PMC Article | 02/18/2023 |
| Increased expression of squamous cell carcinoma antigen 1 and 2 in mycosis fungoides and Sezary syndrome", trans "Increased expression of squamous cell carcinoma antigen 1 and 2 in mycosis fungoides and Sezary syndrome. | Increased expression of squamous cell carcinoma antigen 1 and 2 in mycosis fungoides and Sézary syndrome.
Oka K, Miyagawa T, Suga H, Miyagaki T, Mizuno Y, Kamijo H, Hisamoto T, Omori I, Boki H, Oka T, Takahashi-Shishido N, Sugaya M, Sato S. | 11/5/2022 |
| Differences in Thymus and Activation-Regulated Chemokine and Squamous Cell Carcinoma Antigen 2 Levels in Food Protein-Induced Enterocolitis Syndrome and Atopic Dermatitis. | Differences in Thymus and Activation-Regulated Chemokine and Squamous Cell Carcinoma Antigen 2 Levels in Food Protein-Induced Enterocolitis Syndrome and Atopic Dermatitis.
Makita E, Sugawara D, Kuroda S, Itabashi K, Hirakubo Y, Nonaka K, Ichihashi K. | 09/17/2022 |
| Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa. | Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa.
Derakhshan S, Poosti A, Razavi AE, Moosavi MA, Mahdavi N, Naieni FB, Hesari KK, Rahpeima A., Free PMC Article | 12/18/2021 |
| Clinical Significance of Serum Squamous Cell Carcinoma Antigen for Patients with Recurrent Esophageal Squamous Cell Carcinoma. | Clinical Significance of Serum Squamous Cell Carcinoma Antigen for Patients with Recurrent Esophageal Squamous Cell Carcinoma.
Kanie Y, Okamura A, Maruyama S, Sakamoto K, Fujiwara D, Kanamori J, Imamura Y, Watanabe M. | 10/23/2021 |
| Measurement of squamous cell carcinoma antigen 2 in lichen planus patients. | Measurement of squamous cell carcinoma antigen 2 in lichen planus patients.
Khattab FM, Samir MA. | 06/19/2021 |
| Serum SCCA1, SCCA2, periostin and TARC levels were all significantly increased in atopic dermatitis (AD) in Japanese Ishigaki cohort compared with those in non-AD, but only serum SCCA2 showed a significant increase in AD when assessed in each age group or in subgroup analysis and showed the best diagnosability for AD in ROC analysis. | Serum squamous cell carcinoma antigen (SCCA)-2 correlates with clinical severity of pediatric atopic dermatitis in Ishigaki cohort.
Takeuchi S, Furusyo N, Ono J, Azuma Y, Takemura M, Esaki H, Yamamura K, Mitamura Y, Tsuji G, Kiyomatsu-Oda M, Hayashi J, Izuhara K, Furue M. | 04/4/2020 |
| Studied association of progastrin-releasing peptide (proGRP), neuron specific enolase (NSE), chromogranin a (CgA), and squamous cell cancer antigen (SCCA1) in pulmonary neuroendocrine tumor (PNET) and non-small-cell lung carcinoma (NSCLC). Results showed ProGRP can distinguish PNET patients from NSCLC patients, and with adjusted NSE values, it can differentiate the PNET group from the benign disease group. | Clinical significance of progastrin-releasing peptide, neuron-specific enolase, chromogranin a, and squamous cell cancer antigen in pulmonary neuroendocrine tumors.
Tutar N, Yetkin NA, Yazıcı C, Önal Ö, Kontaş O, Keleştemur F., Free PMC Article | 02/22/2020 |
| serum SCCA can not only be used in diagnosis and prognosis of squamous cell carcinomas but also as biomarkers for uremia, azotemia, diabetic nephropathy, and nephritic syndrome. | Serum SCCA levels in patients suffering cancers or other diseases.
Yang D, Wang J, Zhang L. | 02/1/2020 |
| this study shows that SERPINB4 contributes to survival of allergenic TH2 cells | Antiapoptotic serine protease inhibitors contribute to survival of allergenic T(H)2 cells.
Shamji MH, Temblay JN, Cheng W, Byrne SM, Macfarlane E, Switzer AR, Francisco NDC, Olexandra F, Jacubczik F, Durham SR, Ashton-Rickardt PG., Free PMC Article | 08/24/2019 |
| SCCA2 is a reliable biomarker. | SCCA2 is a reliable biomarker for evaluating pediatric atopic dermatitis.
Nagao M, Inagaki S, Kawano T, Azuma Y, Nomura N, Noguchi Y, Ohta S, Kawaguchi A, Odajima H, Ohya Y, Fujisawa T, Izuhara K. | 08/3/2019 |
| Fifty-two of 96 cases (54%) showed evaluated serum SCC antigen levels above the upper limit. The serum SCCA2 level was significantly higher in the head and neck SCC patients than in control group, whereas there were no significant differences in the serum SCCA1 level between head and neck SCC patients and control group. | The clinical value of serum squamous cell carcinoma antigens 1 and 2 in head and neck squamous cell carcinoma.
Yasumatsu R, Nakano T, Hashimoto K, Kogo R, Wakasaki T, Nakagawa T. | 06/15/2019 |
| Results provide evidence that SCCA1 overexpression is associated with poor prognosis in esophageal cancer patients. which is due to reduced tumor chemosensitivity as well as intratumoral immunity impairment, possibly mediated by the induction of the PD-L1 immune checkpoint regulator. | Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity.
Turato C, Scarpa M, Kotsafti A, Cappon A, Quarta S, Biasiolo A, Cavallin F, Trevellin E, Guzzardo V, Fassan M, Chiarion-Sileni V, Castoro C, Rugge M, Vettor R, Scarpa M, Pontisso P., Free PMC Article | 05/18/2019 |
| While novel diagnostic tumour markers are urgently needed, the examined potential tumour markers, with the exception of PIVKAII seem to be inadequate for diagnosing HCC in ALC | Diagnostic specificity and sensitivity of PIVKAII, GP3, CSTB, SCCA1 and HGF for the diagnosis of hepatocellular carcinoma in patients with alcoholic liver cirrhosis.
Unić A, Derek L, Duvnjak M, Patrlj L, Rakić M, Kujundžić M, Renjić V, Štoković N, Dinjar P, Jukic A, Grgurević I. | 01/26/2019 |
| Results provide the first evidence that failure of serum SCCA to fall into the normal range by the fourth week of definitive radiotherapy is associated with significantly increased risk of recurrence and death. | Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.
Markovina S, Wang S, Henke LE, Luke CJ, Pak SC, DeWees T, Pfeifer JD, Schwarz JK, Liu W, Chen S, Mutch D, Wang X, Powell MA, Siegel BA, Dehdashti F, Silverman GA, Grigsby PW., Free PMC Article | 01/5/2019 |
| The combination of SCCA-IgM with common clinical data shows promising diagnostic performance for the detection of Non-alcoholic steato-hepatitis in hepatitis C virus patients | Development of a novel diagnostic algorithm to predict NASH in HCV-positive patients.
Gallotta A, Paneghetti L, Mrázová V, Bednárová A, Kružlicová D, Frecer V, Miertus S, Biasiolo A, Martini A, Pontisso P, Fassina G. | 09/29/2018 |
| Both periostin and SCCA may play a role in the pathogenesis of acute bronchitis due to respiratory syncytial virus | Up-regulation of serum periostin and squamous cell carcinoma antigen levels in infants with acute bronchitis due to respiratory syncytial virus.
Nakamura H, Akashi K, Watanabe M, Ohta S, Ono J, Azuma Y, Ogasawara N, Yamamoto K, Shimizu N, Tsutsumi H, Izuhara K, Katsunuma T. | 09/22/2018 |
| Findings point to potential interest of squamous cell carcinoma antigen SERPINB3/B4 for the stratification of head and neck squamous cell carcinoma (HNSCC) patients in the therapeutic context. | Squamous Cell Carcinoma Antigen-encoding Genes SERPINB3/B4 as Potentially Useful Markers for the Stratification of HNSCC Tumours.
Saidak Z, Morisse MC, Chatelain D, Sauzay C, Houessinon A, Guilain N, Soyez M, Chauffert B, Dakpé S, Galmiche A. | 03/17/2018 |
| Serum SCCA2 levels reflected disease severity and clinical type of atopic dermatitis. Serum SCCA2 may thus be a relevant biomarker for atopic dermatitis. | Serum levels of squamous cell carcinoma antigens 1 and 2 reflect disease severity and clinical type of atopic dermatitis in adult patients.
Okawa T, Yamaguchi Y, Kou K, Ono J, Azuma Y, Komitsu N, Inoue Y, Kohno M, Matsukura S, Kambara T, Ohta S, Izuhara K, Aihara M. | 01/27/2018 |
| role of SERPINB3/B4 mutations in immunotherapy response | Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy.
Riaz N, Havel JJ, Kendall SM, Makarov V, Walsh LA, Desrichard A, Weinhold N, Chan TA., Free PMC Article | 09/9/2017 |
| Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1, SERPINB4 and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors. | Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors.
van Kempen PM, Noorlag R, Swartz JE, Bovenschen N, Braunius WW, Vermeulen JF, Van Cann EM, Grolman W, Willems SM., Free PMC Article | 09/10/2016 |
| Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC-I and CD1d expression. Intriguingly, expression of SERPINB9, SERPINB1, and SERPINB4 is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors | Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors.
Vermeulen JF, van Hecke W, Spliet WG, Villacorta Hidalgo J, Fisch P, Broekhuizen R, Bovenschen N., Free PMC Article | 08/6/2016 |
| It is a promising serological marker for hepatocellular carcinoma. | Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).
Pozzan C, Cardin R, Piciocchi M, Cazzagon N, Maddalo G, Vanin V, Giacomin A, Pontisso P, Cillo U, Farinati F. | 04/11/2015 |
| Silencing of SERPINB3/B4 in human keratinocytes decreased S100A8 expression, supporting a role for SERPINB3/B4 in the initiation of the acute inflammatory response. | SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.
Sivaprasad U, Kinker KG, Ericksen MB, Lindsey M, Gibson AM, Bass SA, Hershey NS, Deng J, Medvedovic M, Khurana Hershey GK., Free PMC Article | 02/28/2015 |
| we identified four proteins with different expression in paclitaxel resistant cells, i.e., serpin B3, serpin B4, heat shock protein 27 (all three upregulated) and cytokeratin 18 (downregulated). | Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel.
Pavlikova N, Bartonova I, Dincakova L, Halada P, Kovar J. | 01/31/2015 |