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    S100A11 S100 calcium binding protein A11 [ Homo sapiens (human) ]

    Gene ID: 6282, updated on 10-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs.

    Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs.
    Deng C, Xu Y, Chen H, Zhu X, Huang L, Chen Z, Xu H, Song G, Lu J, Huang W, Liu R, Tang Q, Wang J.

    03/5/2024
    Downregulation of S100A11 promotes T cell infiltration by regulating cancer-associated fibroblasts in prostate cancer.

    Downregulation of S100A11 promotes T cell infiltration by regulating cancer-associated fibroblasts in prostate cancer.
    Han D, Guo C, Cheng H, Lu J, Hou Z, Zhang X, Luo Y, Zhang B, Zhao W, Shang P.

    02/14/2024
    Exploring the prognostic value of S100A11 and its association with immune infiltration in breast cancer.

    Exploring the prognostic value of S100A11 and its association with immune infiltration in breast cancer.
    He J, Lei Y, Li X, Wu B, Tang Y., Free PMC Article

    01/3/2024
    S100A11 Promotes Metastasis via AKT and ERK Signaling Pathways and Has a Diagnostic Role in Hepatocellular Carcinoma.

    S100A11 Promotes Metastasis via AKT and ERK Signaling Pathways and Has a Diagnostic Role in Hepatocellular Carcinoma.
    Zheng M, Meng H, Li Y, Shi J, Han Y, Zhao C, Chen J, Han J, Liang J, Chen Y, Liu Q, Wang Y., Free PMC Article

    03/3/2023
    Inhibitory Effect of S100A11 on Airway Smooth Muscle Contraction and Airway Hyperresponsiveness.

    Inhibitory Effect of S100A11 on Airway Smooth Muscle Contraction and Airway Hyperresponsiveness.
    Cheng M, Shi YL, Shang PP, Chen YJ, Xu YD.

    04/30/2022
    Tranilast inhibits angiotensin II-induced myocardial fibrosis through S100A11/ transforming growth factor-beta (TGF-beta1)/Smad axis.

    Tranilast inhibits angiotensin II-induced myocardial fibrosis through S100A11/ transforming growth factor-β (TGF-β1)/Smad axis.
    Chen Y, Huang M, Yan Y, He D., Free PMC Article

    02/19/2022
    Circular RNA FOXP1 relieves trophoblastic cell dysfunction in recurrent pregnancy loss via the miR-143-3p/S100A11 cascade.

    Circular RNA FOXP1 relieves trophoblastic cell dysfunction in recurrent pregnancy loss via the miR-143-3p/S100A11 cascade.
    Gao Y, Tang Y, Sun Q, Guan G, Wu X, Shi F, Zhou Z, Yang W., Free PMC Article

    02/19/2022
    S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.

    S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
    Liu C, Du H, Wang Y, Gong N, Qi W, Zhou X, Shi L.

    12/25/2021
    S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.

    S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.
    Zhang L, Zhang Z, Li C, Zhu T, Gao J, Zhou H, Zheng Y, Chang Q, Wang M, Wu J, Ran L, Wu Y, Miao H, Zou X, Liang B., Free PMC Article

    12/25/2021
    S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.

    S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.
    Wang H, Yin M, Ye L, Gao P, Mao X, Tian X, Xu Z, Dai X, Cheng H., Free PMC Article

    12/4/2021
    S100A11 (calgizzarin) is released via NETosis in rheumatoid arthritis (RA) and stimulates IL-6 and TNF secretion by neutrophils.

    S100A11 (calgizzarin) is released via NETosis in rheumatoid arthritis (RA) and stimulates IL-6 and TNF secretion by neutrophils.
    Navrátilová A, Bečvář V, Baloun J, Damgaard D, Nielsen CH, Veigl D, Pavelka K, Vencovský J, Šenolt L, Andrés Cerezo L., Free PMC Article

    10/16/2021
    Serum S100A6, S100A8, S100A9 and S100A11 proteins in colorectal neoplasia: results of a single centre prospective study.

    Serum S100A6, S100A8, S100A9 and S100A11 proteins in colorectal neoplasia: results of a single centre prospective study.
    Moravkova P, Kohoutova D, Vavrova J, Bures J.

    07/17/2021
    Serum Levels of S100A11 and MMP-9 in Patients with Epithelial Ovarian Cancer and Their Clinical Significance.

    Serum Levels of S100A11 and MMP-9 in Patients with Epithelial Ovarian Cancer and Their Clinical Significance.
    Li W, Cui Z, Kong Y, Liu X, Wang X., Free PMC Article

    05/29/2021
    The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.

    The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
    Teng F, Jiang J, Zhang J, Yuan Y, Li K, Zhou B, Zhou X, Liu W, Zhang P, Liu D, Zheng M, Lu Y, Zhang H.

    04/13/2021
    S100A11 functions as novel oncogene in glioblastoma via S100A11/ANXA2/NF-kappaB positive feedback loop.

    S100A11 functions as novel oncogene in glioblastoma via S100A11/ANXA2/NF-κB positive feedback loop.
    Tu Y, Xie P, Du X, Fan L, Bao Z, Sun G, Zhao P, Chao H, Li C, Zeng A, Pan M, Ji J., Free PMC Article

    09/5/2020
    The authors report an accumulation of S100A11 protein in the muscle tissue of patients with myositis, particularly in the regenerating and necrotizing muscle fibres.

    Pro-inflammatory S100A11 is elevated in inflammatory myopathies and reflects disease activity and extramuscular manifestations in myositis.
    Andrés Cerezo L, Hulejová H, Šumová B, Kropáčková T, Kryštůfková O, Klein M, Mann HF, Zámečník J, Pecha O, Pavelka K, Vencovský J, Šenolt L.

    06/13/2020
    Because of the formation of the annexin A1/S100A11 complex.

    Mesoglycan induces keratinocyte activation by triggering syndecan-4 pathway and the formation of the annexin A1/S100A11 complex.
    Bizzarro V, Belvedere R, Pessolano E, Parente L, Petrella F, Perretti M, Petrella A.

    05/30/2020
    The LINC00997-STAT3-S100A11 axis may promote the development of kidney renal clear cell carcinoma.

    LINC00997, a novel long noncoding RNA, contributes to metastasis via regulation of S100A11 in kidney renal clear cell carcinoma.
    Chang Y, Li N, Yuan W, Wang G, Wen J.

    03/21/2020
    our data reveal a novel role of the secretory S100A11 in PDAC disseminative progression through activation of surrounding fibroblasts triggered by the S100A11-RAGE-TPL2-COX2 pathway. The findings of this study will contribute to the establishment of a novel therapeutic antidote to PDACs that are difficult to treat by regulating cancer-associated fibroblasts (CAFs) through targeting the identified pathway

    Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts.
    Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M., Free PMC Article

    01/11/2020
    our results support the notion that S100A11 secretion induced by PDAC cells initiates a paracrine activation loop through the RAGE-mTOR-p70 S6 kinase-mediated proliferation pathway in adjacent fibroblasts

    Extracellular S100A11 Plays a Critical Role in Spread of the Fibroblast Population in Pancreatic Cancers.
    Takamatsu H, Yamamoto KI, Tomonobu N, Murata H, Inoue Y, Yamauchi A, Sumardika IW, Chen Y, Kinoshita R, Yamamura M, Fujiwara H, Mitsui Y, Araki K, Futami J, Saito K, Iioka H, Ruma IMW, Putranto EW, Nishibori M, Kondo E, Yamamoto Y, Toyooka S, Sakaguchi M., Free PMC Article

    12/7/2019
    High S100A11 expression is associated with intrahepatic cholangiocarcinoma.

    S100A11 promotes cell proliferation via P38/MAPK signaling pathway in intrahepatic cholangiocarcinoma.
    Zhang MX, Gan W, Jing CY, Zheng SS, Yi Y, Zhang J, Xu X, Lin JJ, Zhang BH, Qiu SJ., Free PMC Article

    07/6/2019
    this study shows that alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii

    Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii.
    Safronova A, Araujo A, Camanzo ET, Moon TJ, Elliott MR, Beiting DP, Yarovinsky F., Free PMC Article

    05/25/2019
    findings revealed that S100A11 and TGF-beta1/SMAD4 signaling pathway were related but mutually independent in regulating PANC-1 cells proliferation and apoptosis.

    Correlation between S100A11 and the TGF-β(1)/SMAD4 pathway and its effects on the proliferation and apoptosis of pancreatic cancer cell line PANC-1.
    Ji YF, Li T, Jiang F, Ni WK, Guan CQ, Liu ZX, Lu CH, Ni RZ, Wu W, Xiao MB.

    03/30/2019
    Our present study indicated that S100A11 promotes EMT through accumulation of TGF-beta1 expression, and TGF-beta1-induced upregulation of p-SMAD2 and 3.

    S100A11 promotes TGF-β1-induced epithelial-mesenchymal transition through SMAD2/3 signaling pathway in intrahepatic cholangiocarcinoma.
    Zhang M, Zheng S, Jing C, Zhang J, Shen H, Xu X, Lin J, Zhang B.

    10/6/2018
    Results show that S100A11 expression is up-regulated by BC200 through stabilizing its mRNA and that S100A11 critically mediates the ability of BC200 RNA to induce cancer cell migration and invasion.

    Knockdown of BC200 RNA expression reduces cell migration and invasion by destabilizing mRNA for calcium-binding protein S100A11.
    Shin H, Lee J, Kim Y, Jang S, Lee Y, Kim S, Lee Y., Free PMC Article

    07/28/2018
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