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    S100A10 S100 calcium binding protein A10 [ Homo sapiens (human) ]

    Gene ID: 6281, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    S100A10 promotes cancer metastasis via recruitment of MDSCs within the lungs.

    S100A10 promotes cancer metastasis via recruitment of MDSCs within the lungs.
    Li J, Zhou C, Gao X, Tan T, Zhang M, Li Y, Chen H, Wang R, Wang B, Liu J, Liu P., Free PMC Article

    07/31/2024
    Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells.

    Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells.
    Ito S, Kuromiya K, Sekai M, Sako H, Sai K, Morikawa R, Mukai Y, Ida Y, Anzai M, Ishikawa S, Kozawa K, Shirai T, Tanimura N, Sugie K, Ikenouchi J, Ogawa M, Naguro I, Ichijo H, Fujita Y., Free PMC Article

    11/3/2023
    [S100A10 promotes proliferation and invasion of lung adenocarcinoma cells by activating the Akt-mTOR signaling pathway].

    [S100A10 promotes proliferation and invasion of lung adenocarcinoma cells by activating the Akt-mTOR signaling pathway].
    Wang H, Sun Z, Zhao W, Geng B., Free PMC Article

    06/21/2023
    S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos.

    S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos.
    Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO., Free PMC Article

    06/9/2023
    S100 calcium-binding protein A10 contributes to malignant traits in osteosarcoma cells by regulating glycolytic metabolism via the AKT/mTOR pathway.

    S100 calcium-binding protein A10 contributes to malignant traits in osteosarcoma cells by regulating glycolytic metabolism via the AKT/mTOR pathway.
    Ling F, Lu Q., Free PMC Article

    05/28/2022
    The prognostic value of S100A calcium binding protein family members in predicting severe forms of COVID-19.

    The prognostic value of S100A calcium binding protein family members in predicting severe forms of COVID-19.
    Bagheri-Hosseinabadi Z, Abbasi M, Kahnooji M, Ghorbani Z, Abbasifard M., Free PMC Article

    03/19/2022
    The S100A10-AnxA2 complex is associated with the exocytosis of hepatitis B virus in intrauterine infection.

    The S100A10-AnxA2 complex is associated with the exocytosis of hepatitis B virus in intrauterine infection.
    Bai X, Ran J, Zhao X, Liang Y, Yang X, Xi Y., Free PMC Article

    02/19/2022
    Mechanism of Zn(2+) and Ca(2+) Binding to Human S100A1.

    Mechanism of Zn(2+) and Ca(2+) Binding to Human S100A1.
    Baksheeva VE, Roman AY, Villard C, Devred F, Byrne D, Yatoui D, Zalevsky AO, Vologzhannikova AA, Sokolov AS, Permyakov SE, Golovin AV, Shaw GS, Tsvetkov PO, Zernii EY., Free PMC Article

    01/22/2022
    The ANXA2/S100A10 Complex-Regulation of the Oncogenic Plasminogen Receptor.

    The ANXA2/S100A10 Complex-Regulation of the Oncogenic Plasminogen Receptor.
    Bharadwaj AG, Kempster E, Waisman DM., Free PMC Article

    01/22/2022
    The Annexin A2/S100A10 Complex: The Mutualistic Symbiosis of Two Distinct Proteins.

    The Annexin A2/S100A10 Complex: The Mutualistic Symbiosis of Two Distinct Proteins.
    Bharadwaj A, Kempster E, Waisman DM., Free PMC Article

    01/15/2022
    Regulation of S100A10 Gene Expression.

    Regulation of S100A10 Gene Expression.
    Głowacka A, Bieganowski P, Jurewicz E, Leśniak W, Wilanowski T, Filipek A., Free PMC Article

    09/25/2021
    Structural characterization of a dimeric complex between the short cytoplasmic domain of CEACAM1 and the pseudo tetramer of S100A10-Annexin A2 using NMR and molecular dynamics.

    Structural characterization of a dimeric complex between the short cytoplasmic domain of CEACAM1 and the pseudo tetramer of S100A10-Annexin A2 using NMR and molecular dynamics.
    Hu W, Bhattacharya S, Hong T, Wong P, Li L, Vaidehi N, Kalkum M, Shively JE., Free PMC Article

    04/17/2021
    Membranous overexpression of S100A10 is associated with a high-grade cellular status of breast carcinoma.

    Membranous overexpression of S100A10 is associated with a high-grade cellular status of breast carcinoma.
    Arai K, Iwasaki T, Sonoda A, Endo A.

    03/13/2021
    Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.

    Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.
    Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan NL, Wang R, Wang YJ, Semenza GL., Free PMC Article

    02/13/2021
    Annexin A2-S100A10 Represents the Regulatory Component of Maxi-Cl Channel Dependent on Protein Tyrosine Dephosphorylation and Intracellular Ca(2)(+).

    Annexin A2-S100A10 Represents the Regulatory Component of Maxi-Cl Channel Dependent on Protein Tyrosine Dephosphorylation and Intracellular Ca²⁺.
    Islam MR, Okada T, Merzlyak PG, Toychiev AH, Ando-Akatsuka Y, Sabirov RZ, Okada Y.

    01/16/2021
    Upregulation of S100A10 in metastasized breast cancer stem cells.

    Upregulation of S100A10 in metastasized breast cancer stem cells.
    Yanagi H, Watanabe T, Nishimura T, Hayashi T, Kono S, Tsuchida H, Hirata M, Kijima Y, Takao S, Okada S, Suzuki M, Imaizumi K, Kawada K, Minami H, Gotoh N, Shimono Y., Free PMC Article

    01/2/2021
    S100A10 is overexpressed in gastric cancer.S100A10 is succinylated at lysine 47 in gastric cancer.A novel mechanism of S100A10 accumulation mediated by succinylation in gastric cancer, which promotes gastric cancer progression and is regulated by the succinyltransferase CPT1A and SIRT5-mediated desuccinylation.

    CPT1A-mediated succinylation of S100A10 increases human gastric cancer invasion.
    Wang C, Zhang C, Li X, Shen J, Xu Y, Shi H, Mu X, Pan J, Zhao T, Li M, Geng B, Xu C, Wen H, You Q., Free PMC Article

    06/13/2020
    GAS6/AXL signaling activated the expression of S100A10 through SRC to promote plasmin production.

    S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.
    Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB., Free PMC Article

    05/30/2020
    The results of the present study reveal that S100A10 expression can be used as a predictive marker for the prognosis of ovarian cancer and chemosensitivity to carboplatin.

    S100A10 silencing suppresses proliferation, migration and invasion of ovarian cancer cells and enhances sensitivity to carboplatin.
    Wang L, Yan W, Li X, Liu Z, Tian T, Chen T, Zou L, Cui Z., Free PMC Article

    04/25/2020
    This study highlights the complex regulation of p11 by retinoid signaling and challenges the hypothesis that ubiquitin-mediated proteasomal degradation of p11 represents a universal mechanism of regulation of this protein.

    Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)(☆).
    Holloway RW, Thomas ML, Cohen AM, Bharadwaj AG, Rahman M, Marcato P, Marignani PA, Waisman DM., Free PMC Article

    11/16/2019
    the observed reduction in infection is less significant in the absence of S100A10 alone compared to full A2t, supporting an independent role for monomeric AnxA2. More broadly, we show that successful infection by multiple oncogenic HPV types is dependent on A2t.

    Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation.
    Taylor JR, Fernandez DJ, Thornton SM, Skeate JG, Lühen KP, Da Silva DM, Langen R, Kast WM., Free PMC Article

    10/19/2019
    These findings delineate the clinical and functional contribution of S100A10 as a biomarker in pancreatic cancer.

    S100A10, a novel biomarker in pancreatic ductal adenocarcinoma.
    Bydoun M, Sterea A, Liptay H, Uzans A, Huang WY, Rodrigues GJ, Weaver ICG, Gu H, Waisman DM., Free PMC Article

    08/17/2019
    High expression of Annexin A2 and S100A10 in stromal tissue from Epithelial Ovarian Cancer patients was associated with reduced overall survival; however, no independent prognostic value was found for any of the markers.

    Annexin A2 and S100A10 as Candidate Prognostic Markers in Epithelial Ovarian Cancer.
    Christensen MV, Høgdall C, Jensen SG, Lokman N, Ricciardelli C, Christensen IJ, Christiansen P, Brask J, Karlsen MA, Nissen TK, Jochumsen KM, Høgdall E.

    05/25/2019
    The data show that S100A10 expression in lung squamous cell carcinoma is related to invasion of the lymphatic system, cancer stage progress, and a poorer prognosis.

    S100A10 upregulation associates with poor prognosis in lung squamous cell carcinoma.
    Sato K, Saiki Y, Arai K, Ishizawa K, Fukushige S, Aoki K, Abe J, Takahashi S, Sato I, Sakurada A, Okada Y, Horii A.

    05/11/2019
    study has localised AnxA2/S100A10 complexes to key anatomical locations in the placenta and suggests a role for this complex in amniotic epithelium, trophoblasts and syncytium, in addition to its well-known roles in endothelial cells

    Assessment of the cellular localisation of the annexin A2/S100A10 complex in human placenta.
    Abd El-Aleem SA, Dekker LV., Free PMC Article

    11/24/2018
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