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    MIR487A microRNA 487a [ Homo sapiens (human) ]

    Gene ID: 619555, updated on 27-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The prognostic value of miR-487a in clear cell renal cell carcinoma and its influence on cell biological behavior.

    The prognostic value of miR-487a in clear cell renal cell carcinoma and its influence on cell biological behavior.
    Liu S, Zhao Y, Zhao Y, Tang X.

    07/16/2022
    lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p.

    lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p.
    Xia YC, Cao J, Yang J, Zhang Y, Li YS., Free PMC Article

    01/15/2022
    Exosomal miR-487a derived from m2 macrophage promotes the progression of gastric cancer.

    Exosomal miR-487a derived from m2 macrophage promotes the progression of gastric cancer.
    Yang X, Cai S, Shu Y, Deng X, Zhang Y, He N, Wan L, Chen X, Qu Y, Yu S., Free PMC Article

    12/4/2021
    MicroRNA-487a-3p inhibits the growth and invasiveness of oral squamous cell carcinoma by targeting PPM1A.

    MicroRNA-487a-3p inhibits the growth and invasiveness of oral squamous cell carcinoma by targeting PPM1A.
    Wang L, Ge S, Zhou F., Free PMC Article

    11/22/2021
    miR-154-3p and miR-487-3p synergistically modulate RHOA signaling in the carcinogenesis of thyroid cancer.

    miR-154-3p and miR-487-3p synergistically modulate RHOA signaling in the carcinogenesis of thyroid cancer.
    Fan XD, Luo Y, Wang J, An N., Free PMC Article

    03/20/2021
    miR-487a performs oncogenic functions in osteosarcoma by targeting BTG2 mRNA.

    miR-487a performs oncogenic functions in osteosarcoma by targeting BTG2 mRNA.
    Gu Z, Wu S, Xu G, Wu W, Mao B, Zhao S.

    01/9/2021
    MiR-487a-3p suppresses the malignant development of pancreatic cancer by targeting SMAD7.

    MiR-487a-3p suppresses the malignant development of pancreatic cancer by targeting SMAD7.
    Zhou J, Qie S, Fang H, Xi J.

    12/19/2020
    Tumor microRNAs Identified by Small RNA Sequencing as Potential Response Predictors in Locally Advanced Rectal Cancer Patients Treated With Neoadjuvant Chemoradiotherapy.

    Tumor microRNAs Identified by Small RNA Sequencing as Potential Response Predictors in Locally Advanced Rectal Cancer Patients Treated With Neoadjuvant Chemoradiotherapy.
    Machackova T, Trachtova K, Prochazka V, Grolich T, Farkasova M, Fiala L, Sefr R, Kiss I, Skrovina M, Dosoudil M, Berindan-Neagoe I, Svoboda M, Slaby O, Kala Z., Free PMC Article

    11/28/2020
    MicroRNA-487a-3p functions as a new tumor suppressor in prostate cancer by targeting CCND1.

    MicroRNA-487a-3p functions as a new tumor suppressor in prostate cancer by targeting CCND1.
    Wang M, Yu W, Gao J, Ma W, Frentsch M, Thiel A, Liu M, Rahman N, Qin Z, Li X.

    10/24/2020
    The knockdown of microRNA-487a significantly inhibited proliferative, migratory and invasive abilities of esophageal cancer cells but induced cell apoptosis. The protein expression of p62 was remarkably upregulated after microRNA-478a knockdown in esophageal cancer cells.

    MicroRNA-487a promotes proliferation of esophageal cancer cells by inhibiting p62 expression.
    Ma JB, Hu SL, Zang RK, Su Y, Liang YC, Wang Y.

    07/18/2020
    High miR487a expression is associated with osteosarcoma.

    A four serum-miRNA panel serves as a potential diagnostic biomarker of osteosarcoma.
    Huang C, Wang Q, Ma S, Sun Y, Vadamootoo AS, Jin C.

    09/7/2019
    MIR4435-2HG is upregulated in hepatocellular carcinoma and promotes cancer cell proliferation possibly by upregulating miRNA-487a.

    The lncRNA MIR4435-2HG is upregulated in hepatocellular carcinoma and promotes cancer cell proliferation by upregulating miRNA-487a.
    Kong Q, Liang C, Jin Y, Pan Y, Tong D, Kong Q, Zhou J., Free PMC Article

    05/18/2019
    The repression of TIA-1 by miR-487a promoted cell proliferation and suppressed cell apoptosis in vitro, and the knockdown of miR-487a had the opposite effects.

    miR-487a promotes progression of gastric cancer by targeting TIA1.
    Yang X, Wang M, Lin B, Yao D, Li J, Tang X, Li S, Liu Y, Xie R, Yu S.

    12/1/2018
    Study suggests that miR-487a-3p might repress CTLA4 and FOXO3 by binding to their 3'UTRs and contribute to the development of T1D.

    miR-487a-3p upregulated in type 1 diabetes targets CTLA4 and FOXO3.
    Zurawek M, Dzikiewicz-Krawczyk A, Izykowska K, Ziolkowska-Suchanek I, Skowronska B, Czainska M, Podralska M, Fichna P, Przybylski G, Fichna M, Nowak J.

    09/15/2018
    Our findings show that miR-487a, mediated by heat shock factor 1, promotes proliferation and metastasis of Hepatocellular carcinoma (HCC) by PIK3R1 and SPRED2 binding, respectively. Our study provides a rationale for developing miR-487a as a potential prognostic marker or a potential therapeutic target against HCC.

    miRNA-487a Promotes Proliferation and Metastasis in Hepatocellular Carcinoma.
    Chang RM, Xiao S, Lei X, Yang H, Fang F, Yang LY.

    02/24/2018
    miR-487a can directly regulate BCRP expression and reverse chemotherapeutic drug resistance in a subset of breast cancers.

    MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2).
    Ma MT, He M, Wang Y, Jiao XY, Zhao L, Bai XF, Yu ZJ, Wu HZ, Sun ML, Song ZG, Wei MJ.

    11/2/2013
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