| TNF-alpha and RPLP0 drive the apoptosis of endothelial cells and increase susceptibility to high-altitude pulmonary edema. | TNF-α and RPLP0 drive the apoptosis of endothelial cells and increase susceptibility to high-altitude pulmonary edema.
Ge YL, Li PJ, Bu YR, Zhang B, Xu J, He SY, Cao QL, Bai YG, Ma J, Zhang L, Zhou J, Xie MJ., Free PMC Article | 09/23/2024 |
| DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0. | DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0.
Wang YL, Zhao WW, Bai SM, Ma Y, Yin XK, Feng LL, Zeng GD, Wang F, Feng WX, Zheng J, Wang YN, Zeng B, Liu Q, Hung MC, Wan XB., Free PMC Article | 08/27/2022 |
| Phosphorylation of the N-terminal domain of ribosomal P-stalk protein uL10 governs its association with the ribosome. | Phosphorylation of the N-terminal domain of ribosomal P-stalk protein uL10 governs its association with the ribosome.
Filipek K, Michalec-Wawiórka B, Boguszewska A, Kmiecik S, Tchórzewski M. | 05/15/2021 |
| The presence of uL10 on the ribosomes is affected in stressed cells, thus it might be considered as a regulatory element responding to environmental fluctuations. | The uL10 protein, a component of the ribosomal P-stalk, is released from the ribosome in nucleolar stress.
Deryło K, Michalec-Wawiórka B, Krokowski D, Wawiórka L, Hatzoglou M, Tchórzewski M. | 04/7/2018 |
| absence of RPLP0, RPLP1, or RPLP2 resulted in reactive oxygen species (ROS) accumulation and MAPK1/ERK2 signaling pathway activation. | Disruption of the ribosomal P complex leads to stress-induced autophagy.
Artero-Castro A, Perez-Alea M, Feliciano A, Leal JA, Genestar M, Castellvi J, Peg V, Ramón Y Cajal S, Lleonart ME., Free PMC Article | 06/28/2016 |
| This study shows a spontaneous humoral immune response to ribosomal P0 protein in colorectal cancer patients. | Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients.
Benvenuto M, Sileri P, Rossi P, Masuelli L, Fantini M, Nanni M, Franceschilli L, Sconocchia G, Lanzilli G, Arriga R, Faggioni G, Lista F, Orlandi A, Manzari V, Gaspari AL, Modesti A, Bei R., Free PMC Article | 03/19/2016 |
| Down-regulation of RPLP0 resulted in G1 arrest of gastric cancer cells | Dysregulation of apoptotic signaling pathways by interaction of RPLP0 and cathepsin X/Z in gastric cancer.
Teller A, Jechorek D, Hartig R, Adolf D, Reißig K, Roessner A, Franke S. | 10/17/2015 |
| the immune response mediated by serum anti-RPLP0 and anti-galectin 3 antibodies plays a key role in the pathogenesis of SLE skin lesions. These findings provide new insights into the mechanism of SLE-related organ disorders. | Association of anti-acidic ribosomal protein P0 and anti-galectin 3 antibodies with the development of skin lesions in systemic lupus erythematosus.
Shi ZR, Tan GZ, Meng Z, Yu M, Li KW, Yin J, Wei KH, Luo YJ, Jia SQ, Zhang SJ, Wu J, Mi XB, Wang L. | 04/4/2015 |
| Evaluated autoantibodies against native ribosomal P complex and recombinant ribosomal P proteins (anti-Rib-P0, anti-Rib-P1, anti-Rib-P2) for prevalence, diagnostic relevance&clinical associations in a Chinese cohort with systemic lupus erythematosus. | Significance of antibodies against the native ribosomal P protein complex and recombinant P0, P1, and P2 proteins in the diagnosis of Chinese patients with systemic lupus erythematosus.
Li J, Shen Y, He J, Jia R, Wang X, Chen X, Wang D, Han L, Zhu L, Chi X, Saschenbrecker S, Dähnrich C, Stöcker W, Schlumberger W, Li ZG., Free PMC Article | 11/23/2013 |
| Results show that RPL4, RPLP0, and HSPCB were the most stable reference genes in ovarian tissues. | Identification of genes for normalization of quantitative real-time PCR data in ovarian tissues.
Fu J, Bian L, Zhao L, Dong Z, Gao X, Luan H, Sun Y, Song H. | 02/26/2011 |
| P proteins are up-regulated in a considerable number of patients with the most common types of cancer. | Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors.
Artero-Castro A, Castellvi J, García A, Hernández J, Ramón y Cajal S, Lleonart ME. | 02/26/2011 |
| P0 overexpression may cause tumorigenesis in breast and liver tissues at least in part by inhibiting GCIP-mediated tumor suppression. | Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells.
Chang TW, Chen CC, Chen KY, Su JH, Chang JH, Chang MC. | 01/21/2010 |
| Recombinant fusion protein GST.P0 expressed in insect cells, but not the protein obtained in Escherichia coli, had the ability to form a complex with P1 and P2 proteins. | Baculovirus-mediated expression and isolation of human ribosomal phosphoprotein P0 carrying a GST-tag in a functional state.
Abo Y, Hagiya A, Naganuma T, Tohkairin Y, Shiomi K, Kajiura Z, Hachimori A, Uchiumi T, Nakagaki M. | 01/21/2010 |
| The P0 protein was found in the cytoplasm, as well as in the nucleus; however, the nucleoli were excluded. This protein was scattered around the nuclei, and the distribution might reflect association with the so-called nuclear bodies | The subcellular distribution of the human ribosomal "stalk" components: P1, P2 and P0 proteins.
Tchórzewski M, Krokowski D, Rzeski W, Issinger OG, Grankowski N. | 01/21/2010 |