| Replication of [AT/TA]25 Microsatellite Sequences by Human DNA Polymerase delta Holoenzymes Is Dependent on dNTP and RPA Levels. | Replication of [AT/TA](25) Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels.
Pytko KG, Dannenberg RL, Eckert KA, Hedglin M. | 04/22/2024 |
| Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites. | Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites.
Kumar N, Taneja A, Ghosh M, Rothweiler U, Sundaresan NR, Singh M., Free PMC Article | 02/15/2024 |
| Structural characterization of human RPA70N association with DNA damage response proteins. | Structural characterization of human RPA70N association with DNA damage response proteins.
Wu Y, Fu W, Zang N, Zhou C., Free PMC Article | 11/18/2023 |
| Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma. | Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma.
Feng Y, Jiang Y, Liu J, Liu J, Shi M, Chen J, Zhang J, Tian Y, Yang X, Liu H., Free PMC Article | 11/1/2023 |
| Proper RPA acetylation promotes accurate DNA replication and repair. | Proper RPA acetylation promotes accurate DNA replication and repair.
Gan X, Zhang Y, Jiang D, Shi J, Zhao H, Xie C, Wang Y, Xu J, Zhang X, Cai G, Wang H, Huang J, Chen X., Free PMC Article | 06/29/2023 |
| RPA engages telomeric G-quadruplexes more effectively than CST. | RPA engages telomeric G-quadruplexes more effectively than CST.
Olson CL, Barbour AT, Wieser TA, Wuttke DS., Free PMC Article | 06/14/2023 |
| Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation. | Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation.
Greenwood SN, Kulkarni RS, Mikhail M, Weiser BP., Free PMC Article | 05/30/2023 |
| The RPA-RNF20-SNF2H cascade promotes proper chromosome segregation and homologous recombination repair. | The RPA-RNF20-SNF2H cascade promotes proper chromosome segregation and homologous recombination repair.
Li J, Zhao J, Gan X, Wang Y, Jiang D, Chen L, Wang F, Xu J, Pei H, Huang J, Chen X., Free PMC Article | 05/12/2023 |
| PRIMPOL competes with RAD51 to resolve G-quadruplex-induced replication stress via its interaction with RPA. | PRIMPOL competes with RAD51 to resolve G-quadruplex-induced replication stress via its interaction with RPA.
Li T, Tang L, Kou H, Wang F., Free PMC Article | 05/11/2023 |
| The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy. | The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy.
He J, Wang Z, Wang Y, Zou T, Li XP, Chen J., Free PMC Article | 10/29/2022 |
| WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage. | WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage.
Han SS, Wen KK, García-Rubio ML, Wold MS, Aguilera A, Niedzwiedz W, Vyas YM., Free PMC Article | 07/9/2022 |
| Replication protein A associates with nucleolar R loops and regulates rRNA transcription and nucleolar morphology. | Replication protein A associates with nucleolar R loops and regulates rRNA transcription and nucleolar morphology.
Feng S, Manley JL., Free PMC Article | 04/16/2022 |
| Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue. | Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue.
Sharma R, Sahoo SS, Honda M, Granger SL, Goodings C, Sanchez L, Künstner A, Busch H, Beier F, Pruett-Miller SM, Valentine MB, Fernandez AG, Chang TC, Géli V, Churikov D, Hirschi S, Pastor VB, Boerries M, Lauten M, Kelaidi C, Cooper MA, Nicholas S, Rosenfeld JA, Polychronopoulou S, Kannengiesser C, Saintomé C, Niemeyer CM, Revy P, Wold MS, Spies M, Erlacher M, Coulon S, Wlodarski MW., Free PMC Article | 03/5/2022 |
| [Effects of RPA1 down-regulation on the invasion and migration and cell cycle of human nasopharyngeal carcinoma CNE-2R cells with radio resistance]. | [Effects of RPA1 down-regulation on the invasion and migration and cell cycle of human nasopharyngeal carcinoma CNE-2R cells with radio resistance].
Zhang ZX, Lu HY, Yang ZH, Liu CH, Zhan WH, Zhe H, Zhao R. | 12/18/2021 |
| The meiosis-specific MEIOB-SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex. | The meiosis-specific MEIOB-SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex.
Ribeiro J, Dupaigne P, Petrillo C, Ducrot C, Duquenne C, Veaute X, Saintomé C, Busso D, Guerois R, Martini E, Livera G. | 08/21/2021 |
| RPA shields inherited DNA lesions for post-mitotic DNA synthesis. | RPA shields inherited DNA lesions for post-mitotic DNA synthesis.
Lezaja A, Panagopoulos A, Wen Y, Carvalho E, Imhof R, Altmeyer M., Free PMC Article | 07/24/2021 |
| PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments. | PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments.
Li M, Sengupta B, Benkovic SJ, Lee TH, Hedglin M., Free PMC Article | 04/13/2021 |
| Human RPA activates BLM's bidirectional DNA unwinding from a nick. | Human RPA activates BLM's bidirectional DNA unwinding from a nick.
Qin Z, Bi L, Hou XM, Zhang S, Zhang X, Lu Y, Li M, Modesti M, Xi XG, Sun B., Free PMC Article | 04/13/2021 |
| Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair. | Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair.
Caldwell CC, Spies M., Free PMC Article | 03/13/2021 |
| Hydrogen-deuterium exchange reveals a dynamic DNA-binding map of replication protein A. | Hydrogen-deuterium exchange reveals a dynamic DNA-binding map of replication protein A.
Ahmad F, Patterson A, Deveryshetty J, Mattice JR, Pokhrel N, Bothner B, Antony E., Free PMC Article | 03/6/2021 |
| Replication protein A binds RNA and promotes R-loop formation. | Replication protein A binds RNA and promotes R-loop formation.
Mazina OM, Somarowthu S, Kadyrova LY, Baranovskiy AG, Tahirov TH, Kadyrov FA, Mazin AV., Free PMC Article | 02/20/2021 |
| APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A. | APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A.
Wong L, Vizeacoumar FS, Vizeacoumar FJ, Chelico L., Free PMC Article | 01/23/2021 |
| we investigated the intracellular localization of E2F1, RAD51, and replication protein A (RPA) in colon cancer cells exposed to methyl methanesulfonate (MMS), which induces DNA double-strand breaks (DSBs). In cells experiencing DNA damage, the number of RAD51 and RPA foci increased, suggesting that 3'-single-stranded DNAs were exposed | E2F1 facilitates DNA break repair by localizing to break sites and enhancing the expression of homologous recombination factors.
Choi EH, Kim KP., Free PMC Article | 06/27/2020 |
| the reptation mechanism allows single-stranded DNA mobility despite the extensive and high affinity interface of Replication protein A (RPA) with single-stranded DNA | ssDNA diffuses along replication protein A via a reptation mechanism.
Mishra G, Bigman LS, Levy Y., Free PMC Article | 04/4/2020 |
| Combining NMR and X-ray scattering data with comprehensive docking and refinement revealed how XPA DBD and RPA70AB orient on model NER DNA substrates. The structural model enabled design of XPA mutations that inhibit the interaction with RPA70AB | A key interaction with RPA orients XPA in NER complexes.
Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ., Free PMC Article | 03/21/2020 |