| Molecular basis for RASSF10/NPM/RNF2 feedback cascade-mediated regulation of gastric cancer cell proliferation. | Molecular basis for RASSF10/NPM/RNF2 feedback cascade-mediated regulation of gastric cancer cell proliferation.
Lakshmi Ch NP, Sivagnanam A, Raja S, Mahalingam S., Free PMC Article | 08/26/2024 |
| Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells. | Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells.
Araujo-Abad S, Rizzuti B, Soto-Conde L, Vidal M, Abian O, Velazquez-Campoy A, Neira JL, de Juan Romero C. | 08/3/2024 |
| M phase-specific interaction between SBDS and RNF2 at the mitotic spindles regulates mitotic progression. | M phase-specific interaction between SBDS and RNF2 at the mitotic spindles regulates mitotic progression.
Sera Y, Imanaka T, Yamaguchi M. | 11/3/2023 |
| N-Terminally arginylated ubiquitin is attached to histone H2A by RING1B E3 ligase in human cells. | N-Terminally arginylated ubiquitin is attached to histone H2A by RING1B E3 ligase in human cells.
Seo DY, Kim D, Nguyen KT, Oh J, Lee JS, Hwang CS. | 06/2/2023 |
| RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination. | RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination.
Yao L, Li J, Jiang B, Zhang Z, Li X, Ouyang X, Xiao Y, Liu G, Wang Z, Zhang G., Free PMC Article | 04/12/2023 |
| The ubiquitin ligase RNF2 stabilizes ERalpha and modulates breast cancer progression. | The ubiquitin ligase RNF2 stabilizes ERα and modulates breast cancer progression.
Yuan L, Li X, Yang H, Li H., Free PMC Article | 01/14/2023 |
| SPI1 mediates transcriptional activation of TPX2 and RNF2 to regulate the radiosensitivity of lung squamous cell carcinoma. | SPI1 mediates transcriptional activation of TPX2 and RNF2 to regulate the radiosensitivity of lung squamous cell carcinoma.
Yang J, Liu C, Guan J, Wang Y, Su J, Wang Y, Liu S. | 10/29/2022 |
| Hospital-acquired serum phosphate derangements and their associated in-hospital mortality. | Hospital-acquired serum phosphate derangements and their associated in-hospital mortality.
Thongprayoon C, Cheungpasitporn W, Chewcharat A, Petnak T, Mao MA, Srivali N, Bathini T, Vallabhajosyula S, Qureshi F, Kashani K. | 04/23/2022 |
| Rare deleterious de novo missense variants in Rnf2/Ring2 are associated with a neurodevelopmental disorder with unique clinical features. | Rare deleterious de novo missense variants in Rnf2/Ring2 are associated with a neurodevelopmental disorder with unique clinical features.
Luo X, Schoch K, Jangam SV, Bhavana VH, Graves HK, Kansagra S, Jasien JM, Stong N, Keren B, Mignot C, Ravelli C, Undiagnosed Diseases Network, Bellen HJ, Wangler MF, Shashi V, Yamamoto S., Free PMC Article | 04/16/2022 |
| DNA methyltransferase 3 beta regulates promoter methylation of microRNA-149 to augment esophageal squamous cell carcinoma development through the ring finger protein 2/Wnt/beta-catenin axis. | DNA methyltransferase 3 beta regulates promoter methylation of microRNA-149 to augment esophageal squamous cell carcinoma development through the ring finger protein 2/Wnt/β-catenin axis.
Yang J, Zhang Q, Zhao P, Qiao T, Cao Z, Gao F, Liu M, Wu S., Free PMC Article | 04/2/2022 |
| SBDS interacts with RNF2 and is degraded through RNF2-dependent ubiquitination. | SBDS interacts with RNF2 and is degraded through RNF2-dependent ubiquitination.
Sera Y, Sadoya M, Ichinose T, Matsuya S, Imanaka T, Yamaguchi M. | 03/19/2022 |
| HPIP protooncogene differentially regulates metabolic adaptation and cell fate in breast cancer cells under glucose stress via AMPK and RNF2 dependent pathways. | HPIP protooncogene differentially regulates metabolic adaptation and cell fate in breast cancer cells under glucose stress via AMPK and RNF2 dependent pathways.
Penugurti V, Khumukcham SS, Padala C, Dwivedi A, Kamireddy KR, Mukta S, Bhopal T, Manavathi B. | 01/8/2022 |
| RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4. | RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Wang J, Ouyang X, Zhou Z, Mao S, Niu X, Li H, Xu W, Song Y, Cao J, Lai B. | 01/1/2022 |
| The Polycomb protein RING1B enables estrogen-mediated gene expression by promoting enhancer-promoter interaction and R-loop formation. | The Polycomb protein RING1B enables estrogen-mediated gene expression by promoting enhancer-promoter interaction and R-loop formation.
Zhang Y, Liu T, Yuan F, Garcia-Martinez L, Lee KD, Stransky S, Sidoli S, Verdun RE, Zhang Y, Wang Z, Morey L., Free PMC Article | 12/18/2021 |
| Circ_0004104 Accelerates the Progression of Gastric Cancer by Regulating the miR-539-3p/RNF2 Axis. | Circ_0004104 Accelerates the Progression of Gastric Cancer by Regulating the miR-539-3p/RNF2 Axis.
Yue F, Peng K, Zhang L, Zhang J. | 12/11/2021 |
| Distinct Ring1b complexes defined by DEAD-box helicases and EMT transcription factors synergistically enhance E-cadherin silencing in breast cancer. | Distinct Ring1b complexes defined by DEAD-box helicases and EMT transcription factors synergistically enhance E-cadherin silencing in breast cancer.
Wang Y, Sun Y, Shang C, Chen L, Chen H, Wang D, Zeng X., Free PMC Article | 09/18/2021 |
| Ring finger protein 2 promotes colorectal cancer progression by suppressing early growth response 1. | Ring finger protein 2 promotes colorectal cancer progression by suppressing early growth response 1.
Wei F, Jing H, Wei M, Liu L, Wu J, Wang M, Han D, Yang F, Yang B, Jiao D, Zheng G, Zhang L, Xi W, Guo Z, Yang AG, Qin W, Zhou Y, Wen W., Free PMC Article | 05/29/2021 |
| PRC1 catalytic unit RING1B regulates early neural differentiation of human pluripotent stem cells. | PRC1 catalytic unit RING1B regulates early neural differentiation of human pluripotent stem cells.
Desai D, Khanna A, Pethe P. | 03/13/2021 |
| Inhibition of RING1B alters lineage specificity in human embryonic stem cells. | Inhibition of RING1B alters lineage specificity in human embryonic stem cells.
Desai D, Khanna A, Pethe P. | 01/16/2021 |
| Cells depleted of BMI1 or RNF2 showed slower replication forks. | Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency.
Sanchez A, de Vivo A, Tonzi P, Kim J, Huang TT, Kee Y., Free PMC Article | 06/20/2020 |
| the proliferation, metastasis, and EMT were facilitated via knocking down MEG3. In addition, the expression of B lymphoma Mo-MLV insertion region 1 (Bmi1) and RING finger protein 2 was impacted by gain or loss of MEG3, furthermore, the malignant processes induced by MEG3 knockdown were rescued by means of silencing Bmi1. | LncRNA-MEG3 inhibits cell proliferation and invasion by modulating Bmi1/RNF2 in cholangiocarcinoma.
Li J, Jiang X, Li C, Liu Y, Kang P, Zhong X, Cui Y. | 06/13/2020 |
| These data reveal that RNF2 protein plays a vital role in the development of mammary carcinoma | The oncogenic impact of RNF2 on cell proliferation, invasion and migration through EMT on mammary carcinoma.
Wu J, Wang H, Li Q, Guo QY, Tao SQ, Shen YX, Wu ZS. | 02/29/2020 |
| resultant reduction of UBE3A protein level alleviates its effect on ubiquitination-mediated degradation of Ring1B | RYBP modulates stability and function of Ring1B through targeting UBE3A.
Li M, Zhang S, Zhao W, Hou C, Ma X, Li X, Huang B, Chen H, Chen D. | 07/13/2019 |
| MiR-139-5p overexpression combined with inactivation of the MAPK signaling pathway can reverse the cisplatin resistance of OC by suppressing RNF2. | Reversal of cisplatin resistance by microRNA-139-5p-independent RNF2 downregulation and MAPK inhibition in ovarian cancer.
Chen Y, Cao XY, Li YN, Qiu YY, Li YN, Li W, Wang H. | 07/6/2019 |
| The ubiquitin ligase and PRC1 component RNF2/Ring1B is required to support DNA replication. | Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication.
Klusmann I, Wohlberedt K, Magerhans A, Teloni F, Korbel JO, Altmeyer M, Dobbelstein M., Free PMC Article | 03/23/2019 |