| Intracerebroventricular Neuropeptide FF Diminishes the Number of Apneas and Cardiovascular Effects Produced by Opioid Receptors' Activation. | Intracerebroventricular Neuropeptide FF Diminishes the Number of Apneas and Cardiovascular Effects Produced by Opioid Receptors' Activation.
Wojciechowski P, Andrzejewski K, Kaczyńska K., Free PMC Article | 03/6/2021 |
| we demonstrate, for the first time, that NPFFR2 positively modulates the HPA axis via hypothalamic corticotropin-releasing factor (CRF). Our finding that NPFFR2 regulates stress-dependent neural pathways advances our understanding of neuroendocrine regulation and opens new avenues for probing the functions of NPFF. | NPFFR2 Activates the HPA Axis and Induces Anxiogenic Effects in Rodents.
Lin YT, Yu YL, Hong WC, Yeh TS, Chen TC, Chen JC., Free PMC Article | 04/28/2018 |
| Insulin-degrading enzyme is able to degrade specific amino acid sequences present in the neuropeptide pro-NPFFA (NPFF precursor), generating some cryptic peptides that are also observed after incubation with rat brain cortex homogenate. | Metabolism of cryptic peptides derived from neuropeptide FF precursors: the involvement of insulin-degrading enzyme.
Grasso G, Mielczarek P, Niedziolka M, Silberring J., Free PMC Article | 06/27/2015 |
| NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the hypothalamic-pituitary-adrenal axis, through the release of corticotropin releasing hormone. | The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.
Jászberényi M, Bagosi Z, Csabafi K, Palotai M, Telegdy G. | 10/25/2014 |
| the ASIC are tonically active in the vestibular-afferent neurons and modulated by RFamide-like peptides | FMRFamide-related peptide expression in the vestibular-afferent neurons.
Mercado F, López I, Ortega A, Almanza A, Soto E, Vega R. | 08/25/2012 |
| Npff reduces the expression of cocaine-induced conditioned place preference and cocaine-induced sensitization in rats. | Neuropeptide FF (NPFF) reduces the expression of cocaine-induced conditioned place preference and cocaine-induced sensitization in animals.
Kotlinska J, Pachuta A, Silberring J. | 01/21/2010 |
| there are both pro- and anti-opioid actions of NPFF in the parabrachial nucleus to modulate feeding. | Neuropeptide FF exerts pro- and anti-opioid actions in the parabrachial nucleus to modulate food intake.
Nicklous DM, Simansky KJ. | 01/21/2010 |
| NPFF is capable of up-regulating its own gene expression in the solitary nucleus. NPFF may play a homeostatic role in response to specific cardiovascular challenges, such as hypotension. | Central administration of neuropeptide FF (NPFF) causes increased neuronal activation and up-regulation of NPFF gene expression in the rat brainstem.
Jhamandas JH, Mactavish D. | 01/21/2010 |
| NPFF mRNA was found in the embryonic spinal cord, caudal solitary tract nucleus, and surprisingly, in the medullary reticular formation. | Expression of neuropeptide FF, prolactin-releasing peptide, and the receptor UHR1/GPR10 genes during embryogenesis in the rat.
Nieminen ML, Nystedt J, Panula P. | 01/21/2010 |
| neuropeptide FF is not regulated through the vasopressin regulatory system but via an independent pathway. | Neuropeptide FF, but not prolactin-releasing peptide, mRNA is differentially regulated in the hypothalamic and medullary neurons after salt loading.
Kalliomäki ML, Panula P. | 01/21/2010 |
| NPFF facilitates inhibitory input to magnocellular neurosecretory cells of the paraventricular nucleus via GABAergic interneurons located in immediate vicinity of the nucleus. | Neuropeptide FF (NPFF) control of magnocellular neurosecretory cells of the rat hypothalamic paraventricular nucleus (PVN).
Jhamandas JH, MacTavish D, Harris KH. | 01/21/2010 |