| Tumor-intrinsic RGS1 potentiates checkpoint blockade response via ATF3-IFNGR1 axis. | Tumor-intrinsic RGS1 potentiates checkpoint blockade response via ATF3-IFNGR1 axis.
Wang B, Jiang B, Du L, Chen W, Zhang Q, Chen W, Ding M, Cao W, Gao J, Deng Y, Fu Y, Li Y, Xiao Y, Diao W, Guo H., Free PMC Article | 02/29/2024 |
| Regulator of G protein signaling-1 regulates immune infiltration and macrophage polarization in clear cell renal cell carcinoma. | Regulator of G protein signaling-1 regulates immune infiltration and macrophage polarization in clear cell renal cell carcinoma.
Liu K, Xia D, Bian H, Peng L, Dai S, Liu C, Jiang C, Wang Y, Jin J, Bi L., Free PMC Article | 01/30/2024 |
| RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function. | RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function.
Flynn AL, Gans J, Escobedo J, Zhu C, Florescu AM, Shankara S, Madden SL, Kim PS, Pao LI. | 11/30/2023 |
| ATF3 Modulates the Proliferation, Migration, and Apoptosis of Synovial Fibroblasts after Arthroscopy by Promoting RGS1 Transcription. | ATF3 Modulates the Proliferation, Migration, and Apoptosis of Synovial Fibroblasts after Arthroscopy by Promoting RGS1 Transcription.
He X, Deng L, Zou K, Tian Y, Tang X. | 09/21/2023 |
| ScRNA-seq revealed targeting regulator of G protein signaling 1 to mediate regulatory T cells in Hepatocellular carcinoma. | ScRNA-seq revealed targeting regulator of G protein signaling 1 to mediate regulatory T cells in Hepatocellular carcinoma.
Zou L, Liu K, Shi Y, Li G, Li H, Zhao C. | 04/14/2023 |
| Identification of DNA methylation-regulated differentially expressed genes in RA by integrated analysis of DNA methylation and RNA-Seq data. | Identification of DNA methylation-regulated differentially expressed genes in RA by integrated analysis of DNA methylation and RNA-Seq data.
Zhang R, Chang C, Jin Y, Xu L, Jiang P, Wei K, Xu L, Guo S, Sun S, He D., Free PMC Article | 11/5/2022 |
| RGS1 and related genes as potential targets for immunotherapy in cervical cancer: computational biology and experimental validation. | RGS1 and related genes as potential targets for immunotherapy in cervical cancer: computational biology and experimental validation.
Zhang S, Wang H, Liu J, Tao T, Zeng Z, Wang M., Free PMC Article | 07/30/2022 |
| Single-Cell Transcriptome Analysis Reveals RGS1 as a New Marker and Promoting Factor for T-Cell Exhaustion in Multiple Cancers. | Single-Cell Transcriptome Analysis Reveals RGS1 as a New Marker and Promoting Factor for T-Cell Exhaustion in Multiple Cancers.
Bai Y, Hu M, Chen Z, Wei J, Du H., Free PMC Article | 02/19/2022 |
| Targeted resequencing reveals rare variants enrichment in multiple sclerosis susceptibility genes. | Targeted resequencing reveals rare variants enrichment in multiple sclerosis susceptibility genes.
Gil-Varea E, Spataro N, Villar LM, Tejeda-Velarde A, Midaglia L, Matesanz F, Malhotra S, Eixarch H, Patsopoulos N, Fernández Ó, Oliver-Martos B, Saiz A, Llufriu S, Ramió-Torrentà L, Quintana E, Izquierdo G, Alcina A, Bosch E, Navarro A, Montalban X, Comabella M. | 11/6/2021 |
| Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer. | Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer.
Huang D, Chen X, Zeng X, Lao L, Li J, Xing Y, Lu Y, Ouyang Q, Chen J, Yang L, Su F, Yao H, Liu Q, Su S, Song E. | 08/28/2021 |
| Results provide evidence that RGS1 is a target of miR29C that is regulated by TUG1. | Long non-coding RNA TUG1 recruits miR‑29c‑3p from its target gene RGS1 to promote proliferation and metastasis of melanoma cells.
Wang Y, Liu G, Ren L, Wang K, Liu A. | 08/17/2019 |
| Results showed that RGS1 expression was significantly higher in melanoma than that noted in nevus tissue and correlated with reduced diseasespecific survival. Also, RGS1 expression was also found to be related to the proliferation and migration of melanoma cells through regulation of Galphasmediated inactivation of AKT and ERK. | Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation.
Sun MY, Wang Y, Zhu J, Lv C, Wu K, Wang XW, Xue CY. | 09/22/2018 |
| The rs12022418 in RGS1 showed novel associations in IgA nephropathy. | Novel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy.
Zhou XJ, Nath SK, Qi YY, Sun C, Hou P, Zhang YM, Lv JC, Shi SF, Liu LJ, Chen R, Yang W, He KZ, Li Y, Zhang H., Free PMC Article | 05/19/2018 |
| High RGS1 immunohistochemistry expression associates with poor overall survival in diffuse large B cell lymphoma | Clinicopathological characteristics and genomic profile of primary sinonasal tract diffuse large B cell lymphoma (DLBCL) reveals gain at 1q31 and RGS1 encoding protein; high RGS1 immunohistochemical expression associates with poor overall survival in DLBCL not otherwise specified (NOS).
Carreras J, Kikuti YY, Beà S, Miyaoka M, Hiraiwa S, Ikoma H, Nagao R, Tomita S, Martin-Garcia D, Salaverria I, Sato A, Ichiki A, Roncador G, Garcia JF, Ando K, Campo E, Nakamura N. | 06/24/2017 |
| RGS1 expression may be a prognostic marker for risk stratification and a promising target for the development of a new multiple myeloma therapy. | RGS1 expression is associated with poor prognosis in multiple myeloma.
Roh J, Shin SJ, Lee AN, Yoon DH, Suh C, Park CJ, Huh J, Park CS. | 03/18/2017 |
| Regulator of G-protein signaling 1 rs2816316 was negatively associated with celiac disease . | Meta-Analysis on Associations of RGS1 and IL12A Polymorphisms with Celiac Disease Risk.
Guo CC, Wang M, Cao FD, Huang WH, Xiao D, Ye XG, Ou ML, Zhang N, Zhang BH, Liu Y, Yang G, Jing CX., Free PMC Article | 12/17/2016 |
| RGS1 as a potential marker of CRC tissue quality | Identification and Validation of a Potential Marker of Tissue Quality Using Gene Expression Analysis of Human Colorectal Tissue.
Lange N, Unger FT, Schöppler M, Pursche K, Juhl H, David KA., Free PMC Article | 05/14/2016 |
| RGS1 suppresses CXCL12-mediated migration and AKT activation in cultured human plasmacytoma cells and plasmablasts. | Regulator of G protein signaling 1 suppresses CXCL12-mediated migration and AKT activation in RPMI 8226 human plasmacytoma cells and plasmablasts.
Pak HK, Gil M, Lee Y, Lee H, Lee AN, Roh J, Park CS., Free PMC Article | 04/2/2016 |
| Rgs1 has a role in leukocyte trafficking and vascular inflammation | RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.
Patel J, McNeill E, Douglas G, Hale AB, de Bono J, Lee R, Iqbal AJ, Regan-Komito D, Stylianou E, Greaves DR, Channon KM., Free PMC Article | 08/15/2015 |
| RGS1 and TNFRSF1A polymorphisms tended to be associated with reduced attack severity in Multiple sclerosis. | Multiple sclerosis susceptibility genes: associations with relapse severity and recovery.
Mowry EM, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E., Free PMC Article | 06/7/2014 |
| RGS1 is largely upregulated, whereas RGS2 is downregulated in the majority of solid tumors, whereas RGS5 transcripts are greatly increased in eight subtypes of lymphoma with no reports of downregulation in hematological malignancies | RGS expression in cancer: oncomining the cancer microarray data.
Sethakorn N, Dulin NO. | 01/4/2014 |
| Markers in the RGS1 gene might be in linkage disequilibrium with a protective allele that reduces the risk of anxiety and depressive disorders. | Genetic association between RGS1 and internalizing disorders.
Hettema JM, An SS, van den Oord EJ, Neale MC, Kendler KS, Chen X., Free PMC Article | 10/26/2013 |
| Elevated RGS1 levels profoundly reduce T cell migration to lymphoid-homing chemokines | Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potential.
Gibbons DL, Abeler-Dörner L, Raine T, Hwang IY, Jandke A, Wencker M, Deban L, Rudd CE, Irving PM, Kehrl JH, Hayday AC., Free PMC Article | 10/22/2011 |
| RGS1 is a novel multiple sclerosis susceptibility loci, shared with celieac disease. | IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci.
International Multiple Sclerosis Genetics Conssortium (IMSGC)., Free PMC Article | 10/30/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |