| UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2. | UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.
Langer LM, Kurscheidt K, Basquin J, Bonneau F, Iermak I, Basquin C, Conti E., Free PMC Article | 06/11/2024 |
| UPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency. | UPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency.
Chapman JH, Youle AM, Grimme AL, Neuman KC, Hogg JR., Free PMC Article | 06/10/2024 |
| UPF1 regulates mRNA stability by sensing poorly translated coding sequences. | UPF1 regulates mRNA stability by sensing poorly translated coding sequences.
Musaev D, Abdelmessih M, Vejnar CE, Yartseva V, Weiss LA, Strayer EC, Takacs CM, Giraldez AJ., Free PMC Article | 05/9/2024 |
| LncRNA GAS5 regulated by FTO-mediated m6A demethylation promotes autophagic cell death in NSCLC by targeting UPF1/BRD4 axis. | LncRNA GAS5 regulated by FTO-mediated m6A demethylation promotes autophagic cell death in NSCLC by targeting UPF1/BRD4 axis.
Fu Y, Liu L, Wu H, Zheng Y, Zhan H, Li L. | 04/4/2024 |
| Nonsense-mediated mRNA decay affects hyperactive root formation in oculo-facio-cardio-dental syndrome via up-frameshift protein 1. | Nonsense-mediated mRNA decay affects hyperactive root formation in oculo-facio-cardio-dental syndrome via up-frameshift protein 1.
Machida R, Ogawa T, Min Soe K, Moriyama K. | 03/11/2024 |
| LINC02561 promotes metastasis in HCC via HIF1-alpha/NDRG1/UPF1 axis. | LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
Li SN, Li MX, Guo WW, Zhang LR, Ding YH, Wu XJ. | 01/12/2024 |
| Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells. | Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells.
Jung S, Ko SH, Ahn N, Lee J, Park CH, Hwang J., Free PMC Article | 01/9/2024 |
| YTHDF2 facilitates aggresome formation via UPF1 in an m[6]A-independent manner. | YTHDF2 facilitates aggresome formation via UPF1 in an m(6)A-independent manner.
Hwang HJ, Park TL, Kim HI, Park Y, Kim G, Song C, Cho WK, Kim YK., Free PMC Article | 10/13/2023 |
| Synergistic Binding of ATP and Nucleic Acids Necessitates UPF1's ATPase Functional Cycle. | Synergistic Binding of ATP and Nucleic Acids Necessitates UPF1's ATPase Functional Cycle.
Sun B, Liu T, Zhang M, Li S. | 06/13/2023 |
| UPF1 regulates FOXO1 protein expression by promoting PBK transcription in non-small cell lung cancer. | UPF1 regulates FOXO1 protein expression by promoting PBK transcription in non-small cell lung cancer.
Wang P, Li T, Fang L, Chen D, Qi H, Gu C. | 06/13/2023 |
| UPF1-From mRNA Degradation to Human Disorders. | UPF1-From mRNA Degradation to Human Disorders.
Staszewski J, Lazarewicz N, Konczak J, Migdal I, Maciaszczyk-Dziubinska E., Free PMC Article | 02/15/2023 |
| Modulation of RNA-binding properties of the RNA helicase UPF1 by its activator UPF2. | Modulation of RNA-binding properties of the RNA helicase UPF1 by its activator UPF2.
Xue G, Maciej VD, Machado de Amorim A, Pak M, Jayachandran U, Chakrabarti S., Free PMC Article | 01/28/2023 |
| Identification and Validation of UPF1 as a Novel Prognostic Biomarker in Renal Clear Cell Carcinoma. | Identification and Validation of UPF1 as a Novel Prognostic Biomarker in Renal Clear Cell Carcinoma.
Wu C, Li H, Chang W, Zhong L, Zhang L, Wen Z, Mai S., Free PMC Article | 12/3/2022 |
| UPF1 increases amino acid levels and promotes cell proliferation in lung adenocarcinoma via the eIF2alpha-ATF4 axis. | UPF1 increases amino acid levels and promotes cell proliferation in lung adenocarcinoma via the eIF2α-ATF4 axis.
Fang L, Qi H, Wang P, Wang S, Li T, Xia T, Piao H, Gu C., Free PMC Article | 10/22/2022 |
| The edited UPF1 is correlated with elevated asparagine synthetase in pancreatic ductal adenocarcinomas. | The edited UPF1 is correlated with elevated asparagine synthetase in pancreatic ductal adenocarcinomas.
Hu J, Wang Z, Yang S, Lu Y, Li G. | 06/18/2022 |
| An alternative UPF1 isoform drives conditional remodeling of nonsense-mediated mRNA decay. | An alternative UPF1 isoform drives conditional remodeling of nonsense-mediated mRNA decay.
Fritz SE, Ranganathan S, Wang CD, Hogg JR., Free PMC Article | 05/21/2022 |
| The biological behavior of tRNA-derived fragment tRF-Leu-AAG in pancreatic cancer cells. | The biological behavior of tRNA-derived fragment tRF-Leu-AAG in pancreatic cancer cells.
Sui S, Wang Z, Cui X, Jin L, Zhu C., Free PMC Article | 05/7/2022 |
| The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma. | The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma.
Polaski JT, Udy DB, Escobar-Hoyos LF, Askan G, Leach SD, Ventura A, Kannan R, Bradley RK., Free PMC Article | 04/30/2022 |
| Up-frameshift Protein 1 Promotes Tumor Progression by Regulating Apoptosis and Epithelial-Mesenchymal Transition of Colorectal Cancer. | Up-frameshift Protein 1 Promotes Tumor Progression by Regulating Apoptosis and Epithelial-Mesenchymal Transition of Colorectal Cancer.
Chen B, Wang H, Li D, Lin X, Ma Z, Zeng Y., Free PMC Article | 03/12/2022 |
| UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. | UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.
Zaepfel BL, Zhang Z, Maulding K, Coyne AN, Cheng W, Hayes LR, Lloyd TE, Sun S, Rothstein JD., Free PMC Article | 01/29/2022 |
| UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma. | UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q., Free PMC Article | 01/8/2022 |
| UPF1: a potential biomarker in human cancers. | UPF1: a potential biomarker in human cancers.
Chen BL, Wang HM, Lin XS, Zeng YM. | 01/1/2022 |
| A role for AKT1 in nonsense-mediated mRNA decay. | A role for AKT1 in nonsense-mediated mRNA decay.
Palma M, Leroy C, Salomé-Desnoulez S, Werkmeister E, Kong R, Mongy M, Le Hir H, Lejeune F., Free PMC Article | 12/25/2021 |
| UPF1 promotes chemoresistance to oxaliplatin through regulation of TOP2A activity and maintenance of stemness in colorectal cancer. | UPF1 promotes chemoresistance to oxaliplatin through regulation of TOP2A activity and maintenance of stemness in colorectal cancer.
Zhu C, Zhang L, Zhao S, Dai W, Xu Y, Zhang Y, Zheng H, Sheng W, Xu Y., Free PMC Article | 10/16/2021 |
| UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair. | UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair.
Ngo GHP, Grimstead JW, Baird DM., Free PMC Article | 07/24/2021 |