PIM1-Induced Cytoplasmic Expression of RBMY Mediates Hepatocellular Carcinoma Metastasis. | PIM1-Induced Cytoplasmic Expression of RBMY Mediates Hepatocellular Carcinoma Metastasis. Chua HH, Chang MH, Chen YH, Tsuei DJ, Jeng YM, Lee PH, Ni YH., Free PMC Article | 12/31/2022 |
Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis. | Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis. Kido T, Tabatabai ZL, Chen X, Lau YC., Free PMC Article | 12/12/2020 |
genetic association study in population in southwest China: Data suggest that copy number variation in RBMY1 is associated with sperm motility and asthenozoospermia; RBMY1 functional copy dosage is positively correlated with sperm motility; dosage insufficiency is independent genetic risk factor for asthenozoospermia; RBMY1 is an important candidate for male infertility in azoospermia factor (AZF) region of Y-chromosome. | Copy number variation of functional RBMY1 is associated with sperm motility: an azoospermia factor-linked candidate for asthenozoospermia. Yan Y, Yang X, Liu Y, Shen Y, Tu W, Dong Q, Yang D, Ma Y, Yang Y. | 06/16/2018 |
RBMY is a novel oncofetal protein that plays a key role in attenuating glycogen synthase kinase 3beta activity, leading to aberrant activation of Wnt/beta-catenin signaling, which facilitates malignant hepatic stemness. | RBMY, a novel inhibitor of glycogen synthase kinase 3β, increases tumor stemness and predicts poor prognosis of hepatocellular carcinoma. Chua HH, Tsuei DJ, Lee PH, Jeng YM, Lu J, Wu JF, Su DS, Chen YH, Chien CS, Kao PC, Lee CN, Hu RH, Ni YH, Chang MH. | 02/6/2016 |
results imply that different alternative splicing may happen in testis cells and probably difference of RBMY function during spermatogenesis is due to the differential expression of RBMY protein isoforms. | Expression analysis of RNA-binding motif gene on Y chromosome (RBMY) protein isoforms in testis tissue and a testicular germ cell cancer-derived cell line (NT2). Alikhani M, Sharifi Tabar M, Mirshahvaladi S, Kheimeh A, Sadighi Gilani MA, Sabbaghian M., Free PMC Article | 04/19/2014 |
One possible function of RBMY could be its involvement in sperm motility. | Cellular ontogeny of RBMY during human spermatogenesis and its role in sperm motility. Abid S, Sagare-Patil V, Gokral J, Modi D. | 07/27/2013 |
investigation of role of RBMY in spermatogenesis: isolation and identification of RBMY target mRNAs in testis; RBMY binds to only transcript variant 2 of Nek10; RBMY may take part in alternative splicing of Nek10 | Identifying mRNAs bound by human RBMY protein in the testis. Zeng M, Liang S, Zhao S, Liu Y, Sun H, Zhang S, Ma Y. | 08/6/2011 |
regulates germline-specific splicing events; ectopic expression stimulated the inclusion of a testis-enriched exon | Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}. Dreumont N, Bourgeois CF, Lejeune F, Liu Y, Ehrmann IE, Elliott DJ, Stévenin J. | 06/14/2010 |
germ cell-specific RBMY and hnRNP G-T proteins were more efficient in stimulating TLE4-T incorporation than somatically expressed hnRNP G protein. | The germ cell nuclear proteins hnRNP G-T and RBMY activate a testis-specific exon. Liu Y, Bourgeois CF, Pang S, Kudla M, Dreumont N, Kister L, Sun YH, Stevenin J, Elliott DJ., Free PMC Article | 02/8/2010 |
Patients with complete Sertoli cell-only syndrome (SCOS) did not exhibit RBMY1 gene expression. | Quantification of DDX3Y, RBMY1, DAZ and TSPY mRNAs in testes of patients with severe impairment of spermatogenesis. Lardone MC, Parodi DA, Valdevenito R, Ebensperger M, Piottante A, Madariaga M, Smith R, Pommer R, Zambrano N, Castro A. | 01/21/2010 |
Using systematic evolution of ligands by exponential enrichment, we found that RNA stem-loops capped by a C(A)/(U)CAA pentaloop are high-affinity binding targets for hRBMY. | The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction. Skrisovska L, Bourgeois CF, Stefl R, Grellscheid SN, Kister L, Wenter P, Elliott DJ, Stevenin J, Allain FH., Free PMC Article | 01/21/2010 |
Quantitative real-time PCR assays of this protein gave positive predictive values of 70 per cent for the recovery of sperm from testicular biopsy. | Investigation of DAZ and RBMY1 gene expression in human testis by quantitative real-time PCR. Lavery R, Glennon M, Houghton J, Nolan A, Egan D, Maher M. | 01/21/2010 |
RNA transport element RTE evolved as a high affinity RBM15 ligand to provide a splicing-independent link to NXF1, thereby ensuring efficient nuclear export and expression of retrotransposon transcripts | RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway. Lindtner S, Zolotukhin AS, Uranishi H, Bear J, Kulkarni V, Smulevitch S, Samiotaki M, Panayotou G, Felber BK, Pavlakis GN. | 01/21/2010 |
RBMY is a new candidate oncogene specific for male liver cancer | RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts. Tsuei DJ, Hsu HC, Lee PH, Jeng YM, Pu YS, Chen CN, Lee YC, Chou WC, Chang CJ, Ni YH, Chang MH. | 01/21/2010 |
analyse the presence of DAZ, RBMY1, USP9Y, protamine-2, SRY and actin messenger RNA (mRNA) in testicular cells of men suffering from idiopathic azoospermia (RBMY1) | A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men. Friel A, Houghton JA, Glennon M, Lavery R, Smith T, Nolan A, Maher M. | 01/21/2010 |