| Overexpression of RBM4 promotes acute myeloid leukemia cell differentiation by regulating alternative splicing of TFEB. | Overexpression of RBM4 promotes acute myeloid leukemia cell differentiation by regulating alternative splicing of TFEB.
Duan Y, Liu S, Wang J, Yang K, Xu J, Wang Q, Liu J, Hao J, Cui X, Tan Y, Wang H, Li L., Free PMC Article | 11/7/2024 |
| A Comprehensive Prognostic and Immune Infiltration Analysis of RBM4 in Pan-Cancer. | A Comprehensive Prognostic and Immune Infiltration Analysis of RBM4 in Pan-Cancer.
Ding JJ, Wu J, Bian HL, Zong Y, Lu B, Ni L. | 03/4/2024 |
| RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis. | RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.
Chen L, Zhang W, Chen D, Yang Q, Sun S, Dai Z, Li Z, Liang X, Chen C, Jiao Y, Zhi L, Zhao L, Zhang J, Liu X, Zhao J, Li M, Wang Y, Qi Y., Free PMC Article | 05/5/2023 |
| RBM4 inhibits the growth of clear cell renal cell carcinoma by enhancing the stability of p53 mRNA. | RBM4 inhibits the growth of clear cell renal cell carcinoma by enhancing the stability of p53 mRNA.
Jian W, Xue W, Wang T, Yu Y, Cai L, Meng Y, Xia Z, Zhang C. | 03/22/2023 |
| RBM4 regulates cellular senescence via miR1244/SERPINE1 axis. | RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Wang L, Zhang X, Sheng J, Chen L, Zhi L, Zheng Q, Qi Y, Wang L, Zhang J, Zhao J, Wang Y, Liu SX, Sun MZ, Zhang W., Free PMC Article | 01/21/2023 |
| RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression. | RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Han H, Lin T, Wang Z, Song J, Fang Z, Zhang J, You X, Du Y, Ye J, Zhou G. | 01/21/2023 |
| G-Quadruplex Regulation of VEGFA mRNA Translation by RBM4. | G-Quadruplex Regulation of VEGFA mRNA Translation by RBM4.
Niu K, Zhang X, Song Q, Feng Q., Free PMC Article | 02/5/2022 |
| Rbm24 regulates inner-ear-specific alternative splicing and is essential for maintaining auditory and motor coordination. | Rbm24 regulates inner-ear-specific alternative splicing and is essential for maintaining auditory and motor coordination.
Zheng L, Yuan H, Zhang M, Wang C, Cai X, Liu J, Xu XQ., Free PMC Article | 12/4/2021 |
| USP3 promotes proliferation of non-small cell lung cancer through regulating RBM4. | USP3 promotes proliferation of non-small cell lung cancer through regulating RBM4.
Liao XH, Wang Y, Zhong B, Zhu SY. | 03/20/2021 |
| Posttranscriptional regulation of human endogenous retroviruses by RNA-binding motif protein 4, RBM4. | Posttranscriptional regulation of human endogenous retroviruses by RNA-binding motif protein 4, RBM4.
Foroushani AK, Chim B, Wong M, Rastegar A, Smith PT, Wang S, Barbian K, Martens C, Hafner M, Muljo SA., Free PMC Article | 01/9/2021 |
| The SRSF1 and RBM4 constitute an antagonistic mechanism on regulating the splicing profiles of HIF-1alpha gene, which is relevant to the oncogenic signatures of lung cancer cells. | SRSF1 and RBM4 differentially modulate the oncogenic effect of HIF-1α in lung cancer cells through alternative splicing mechanism.
Chang HL, Lin JC. | 03/21/2020 |
| RBM4 can mediate the inflammatory response. | RBM4 modulates the proliferation and expression of inflammatory factors via the alternative splicing of regulatory factors in HeLa cells.
Wang WY, Quan W, Yang F, Wei YX, Chen JJ, Yu H, Xie J, Zhang Y, Li ZF. | 01/25/2020 |
| The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells. | The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells.
Lin JC, Lee YC, Liang YC, Fann YC, Johnson KR, Lin YJ., Free PMC Article | 11/10/2018 |
| hese findings suggest that RBM4 is a new biomarker in gastric cancer, as the reduced expression of this protein is correlated with poor differentiation, lymph node status and distant metastasis | Prognostic value of decreased expression of RBM4 in human gastric cancer.
Yong H, Zhu H, Zhang S, Zhao W, Wang W, Chen C, Ding G, Zhu L, Zhu Z, Liu H, Zhang Y, Wen J, Kang X, Zhu J, Feng Z, Liu B., Free PMC Article | 05/5/2018 |
| RBM4-SRSF3-MAP4K4 constitutes a novel mechanism for manipulating the metastasis of colorectal cancer cells through the JNK1 signaling pathway. | RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell.
Lin JC, Lee YC, Tan TH, Liang YC, Chuang HC, Fann YC, Johnson KR, Lin YJ. | 04/21/2018 |
| TPM1-AS regulates the alternative splicing of TPM1 through an interaction with RBM4 and involves in TPM1-mediated filopodium formation and migration of cancer cells | Natural antisense transcript TPM1-AS regulates the alternative splicing of tropomyosin I through an interaction with RNA-binding motif protein 4.
Huang GW, Zhang YL, Liao LD, Li EM, Xu LY. | 11/18/2017 |
| RBM4 is induced and is involved in the PKM splicing switch and neuronal gene expression during hypoxia-induced neuronal differentiation. | RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.
Su CH, Hung KY, Hung SC, Tarn WY., Free PMC Article | 07/1/2017 |
| alternative splicing patterns were altered by knockdown of RBM4 in several types of neoplasms | Transcriptome-wide targets of alternative splicing by RBM4 and possible role in cancer.
Markus MA, Yang YH, Morris BJ. | 12/17/2016 |
| Loss of RBM4 expression is associated with colorectal cancer. | The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells.
Liang YC, Lin WC, Lin YJ, Lin JC., Free PMC Article | 09/24/2016 |
| The results indicate that the alanine-rich C-terminal domain, in conjunction with its conjoined RNA-binding domain(s), differentially influences the subnuclear localization and biogenesis of RBM4. | Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Chang SH, Chang WL, Lu CC, Tarn WY., Free PMC Article | 05/16/2015 |
| Up-regulation of RBM4 is associated with breast cancer. | Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events.
Lin JC, Lin CY, Tarn WY, Li FY., Free PMC Article | 01/31/2015 |
| RBM4 is a tumor suppressor with therapeutic potential and clinical values as a prognostic factor. | The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.
Wang Y, Chen D, Qian H, Tsai YS, Shao S, Liu Q, Dominguez D, Wang Z., Free PMC Article | 11/22/2014 |
| we propose the emerging role of RBM4 in regulating the adipocyte-specific splicing events and transcription cascade, which subsequently facilitate the development and function of brown adipocyte-like cells. | Emerging role for RNA binding motif protein 4 in the development of brown adipocytes.
Lin JC, Tarn WY, Hsieh WK. | 04/26/2014 |
| role in negative feed-forward loop that disrupts inflammattory cytokine translation following Toll-like receptor 4 response | MicroRNA-146a and RBM4 form a negative feed-forward loop that disrupts cytokine mRNA translation following TLR4 responses in human THP-1 monocytes.
Brudecki L, Ferguson DA, McCall CE, El Gazzar M., Free PMC Article | 04/5/2014 |
| RBM4 homologs exert different effects on 5' splice site utilization and exon selection, and exhibit different subnuclear localization patterns. | Phylogenetic and molecular characterization of the splicing factor RBM4.
Lu CC, Chen TH, Wu JR, Chen HH, Yu HY, Tarn WY., Free PMC Article | 09/28/2013 |