| RBBP4: A novel diagnostic and prognostic biomarker for non-small-cell lung cancer correlated with autophagic cell death. | RBBP4: A novel diagnostic and prognostic biomarker for non-small-cell lung cancer correlated with autophagic cell death.
Zhan Y, Zhang Z, Yin A, Su X, Tang N, Chen Y, Zhang Z, Chen W, Wang J, Wang W., Free PMC Article | 09/16/2024 |
| Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review). | Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review).
Zhan Y, Yin A, Su X, Tang N, Zhang Z, Chen Y, Wang W, Wang J., Free PMC Article | 06/17/2024 |
| Circ_0110498 facilitates the cisplatin resistance of non-small cell lung cancer by mediating the miR-1287-5p/RBBP4 axis. | Circ_0110498 facilitates the cisplatin resistance of non-small cell lung cancer by mediating the miR-1287-5p/RBBP4 axis.
Hao D, Li Y, Shi J, Jiang J., Free PMC Article | 03/28/2023 |
| CircAGO2 promotes colorectal cancer progression by inhibiting heat shock protein family B (small) member 8 via miR-1-3p/retinoblastoma binding protein 4 axis. | CircAGO2 promotes colorectal cancer progression by inhibiting heat shock protein family B (small) member 8 via miR-1-3p/retinoblastoma binding protein 4 axis.
Zhu X, Luo X, Long X, Jiang S, Xie X, Zhang Q, Wang H. | 03/9/2023 |
| RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistance. | RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistance.
Li J, Song C, Gu J, Li C, Zang W, Shi L, Chen L, Zhu L, Zhou M, Wang T, Li H, Qi S, Lu Y. | 03/3/2023 |
| Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development. | Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development.
Xiao L, Dang Y, Hu B, Luo L, Zhao P, Wang S, Zhang K., Free PMC Article | 10/15/2022 |
| RBBP4 plays a vital role in the malignant progression of triple-negative breast cancer by regulating epithelial-mesenchymal transition. | RBBP4 plays a vital role in the malignant progression of triple-negative breast cancer by regulating epithelial-mesenchymal transition.
Zheng Z, Yao X, Liu Y. | 09/24/2022 |
| RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma. | RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.
Mladek AC, Yan H, Tian S, Decker PA, Burgenske DM, Bakken K, Hu Z, He L, Connors MA, Carlson BL, Wilson J, Bommi-Reddy A, Conery A, Eckel-Passow JE, Sarkaria JN, Kitange GJ., Free PMC Article | 08/6/2022 |
| RBBP4 promotes colon cancer malignant progression via regulating Wnt/beta-catenin pathway. | RBBP4 promotes colon cancer malignant progression via regulating Wnt/β-catenin pathway.
Li YD, Lv Z, Zhu WF., Free PMC Article | 08/21/2021 |
| The topology of chromatin-binding domains in the NuRD deacetylase complex. | The topology of chromatin-binding domains in the NuRD deacetylase complex.
Millard CJ, Fairall L, Ragan TJ, Savva CG, Schwabe JWR., Free PMC Article | 01/16/2021 |
| In summary, this is the first study showing the expression of RBBP4 in colon cancer and revealing that RBBP4 up-regulation is significantly associated with poor prognosis in colon cancer pa- tients. | Retinoblastoma binding protein 4 up-regulation is correlated with hepatic metastasis and poor prognosis in colon cancer patients.
Li YD, Lv Z, Xie HY, Zheng SS. | 03/28/2020 |
| The authors suggest that RBBP4 is linked to HIV-1 transcriptional silencing and that it may be a new type of viral transcription inhibitor. | Retinoblastoma binding protein 4 represses HIV-1 long terminal repeat-mediated transcription by recruiting NR2F1 and histone deacetylase.
Wang J, Yang Z, Cheng L, Lu L, Pan K, Yang J, Wu N. | 02/22/2020 |
| The binding interface between AEBP and RBBP4 is relatively small compared with PHF6, histone H3 and FOG-1, indicating that AEBP may not have been the only region that participates in RBBP4 recognition. | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4.
Sun A, Li F, Liu Z, Jiang Y, Zhang J, Wu J, Shi Y., Free PMC Article | 06/15/2019 |
| RBBP4 forms a negatively charged channel that binds to ZNF827 through a network of electrostatic interactions. | Structural and functional characterization of the RBBP4-ZNF827 interaction and its role in NuRD recruitment to telomeres.
Yang SF, Sun AA, Shi Y, Li F, Pickett HA. | 04/6/2019 |
| ARMC12 promotes neuroblastoma progression through interaction with RBBP4. | Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4.
Li D, Song H, Mei H, Fang E, Wang X, Yang F, Li H, Chen Y, Huang K, Zheng L, Tong Q., Free PMC Article | 12/22/2018 |
| BCL11A interacts with histone methyltransferase (PRC2) and histone deacetylase (NuRD and SIN3A) complexes through their common subunit, RBBP4/7. | Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.
Moody RR, Lo MC, Meagher JL, Lin CC, Stevers NO, Tinsley SL, Jung I, Matvekas A, Stuckey JA, Sun D., Free PMC Article | 12/22/2018 |
| RBAP48 overexpression contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3-kinase/protein kinase B pathway suppression. | Overexpression of retinoblastoma‑binding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3‑kinase/protein kinase B pathway suppression.
Jin X, Jiang R, Xiang Y, Fan Z, Wu Z, Yang B, Yang L, Wei S, Yang Y., Free PMC Article | 11/3/2018 |
| The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/RBBP7. | The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.
Schmidberger JW, Sharifi Tabar M, Torrado M, Silva AP, Landsberg MJ, Brillault L, AlQarni S, Zeng YC, Parker BL, Low JK, Mackay JP., Free PMC Article | 04/22/2017 |
| RbAp48 is likely to act as a potent antiretroviral defense. | RbAp48, a novel inhibitory factor that regulates the transcription of human immunodeficiency virus type 1.
Wang J, Yang J, Yang Z, Lu X, Jin C, Cheng L, Wu N. | 03/11/2017 |
| The crystal structure reveals an extensive interface between MTA1 and RBBP4. | The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Millard CJ, Varma N, Saleh A, Morris K, Watson PJ, Bottrill AR, Fairall L, Smith CJ, Schwabe JW., Free PMC Article | 12/24/2016 |
| RBBP4 interacts with ep300 protein to form a complex that drives the expression of methylguanine-DNA-methyltransferase , RAD51, and other selected DNA repair genes through histone acetylation. | Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.
Kitange GJ, Mladek AC, Schroeder MA, Pokorny JC, Carlson BL, Zhang Y, Nair AA, Lee JH, Yan H, Decker PA, Zhang Z, Sarkaria JN., Free PMC Article | 12/17/2016 |
| RbAp48 was identified as critical in the proliferation of hypopharyngeal carcinoma in both in vitro and in vivo experiments. | RbAp48 Is Critical for the Proliferation of Hypopharyngeal Carcinoma.
Bai X, Wang D, Ji H, Zheng L, Lu Y, Tang W, Zhang H, Xu W, Li J, Fei Z, Wang H. | 09/17/2016 |
| RBBP4 functions as a novel regulatory factor to increase the efficiency of importin alpha/beta-mediated nuclear import | Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence.
Tsujii A, Miyamoto Y, Moriyama T, Tsuchiya Y, Obuse C, Mizuguchi K, Oka M, Yoneda Y., Free PMC Article | 04/23/2016 |
| It is associated with episodic memory performance. | Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals.
Barral S, Reitz C, Small SA, Mayeux R., Free PMC Article | 11/14/2015 |
| Our RBBP4-PHF6 complex structure provides insights into the molecular basis of PHF6-NuRD complex interaction and implicates a role for PHF6 in chromatin structure modulation and gene regulation. | Structural basis of plant homeodomain finger 6 (PHF6) recognition by the retinoblastoma binding protein 4 (RBBP4) component of the nucleosome remodeling and deacetylase (NuRD) complex.
Liu Z, Li F, Zhang B, Li S, Wu J, Shi Y., Free PMC Article | 05/23/2015 |