| circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis. | circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis.
Tang L, Yuan L, Yan J, Ge J, Lian Z, Li Z., Free PMC Article | 02/14/2024 |
| Overexpression of RAB27A in Oral Squamous Cell Carcinoma Promotes Tumor Migration and Invasion via Modulation of EGFR Membrane Stability. | Overexpression of RAB27A in Oral Squamous Cell Carcinoma Promotes Tumor Migration and Invasion via Modulation of EGFR Membrane Stability.
Huang J, Yang JG, Ren JG, Xia HF, Chen GH, Fu QY, Zhang LZ, Liu HM, Wang KM, Xie QH, Chen G., Free PMC Article | 09/14/2023 |
| SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression. | SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression.
Bastos N, Castaldo SA, Adem B, Machado JC, Melo CA, Melo SA., Free PMC Article | 08/31/2023 |
| Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A). | Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A).
Brauer N, Maruta Y, Lisci M, Strege K, Oschlies I, Nakamura H, Böhm S, Lehmberg K, Brandhoff L, Ehl S, Parvaneh N, Klapper W, Fukuda M, Griffiths GM, Hennies HC, Niehues T, Ammann S., Free PMC Article | 07/5/2023 |
| Molecular findings and clinical manifestations of 18 Iranian children with Griscelli syndrome type 2: Two novel homozygote mutations in RAB27A gene in a patient. | Molecular findings and clinical manifestations of 18 Iranian children with Griscelli syndrome type 2: Two novel homozygote mutations in RAB27A gene in a patient.
Tajik S, Badalzadeh M, Houshmand M, Alizadeh Z, Moradi L, Hamidieh AA, Shafiei A, Heris JA, Bahram S, Molitor A, Carapito R, Moin M, Fazlollahi MR, Pourpak Z. | 06/30/2023 |
| Rab27a-mediated extracellular vesicle secretion contributes to osteogenesis in periodontal ligament-bone niche communication. | Rab27a-mediated extracellular vesicle secretion contributes to osteogenesis in periodontal ligament-bone niche communication.
Lu Y, Zhao L, Mao J, Liu W, Ma W, Zhao B., Free PMC Article | 06/12/2023 |
| Expression and significant roles of the lncRNA NEAT1/miR-493-5p/Rab27A axis in ulcerative colitis. | Expression and significant roles of the lncRNA NEAT1/miR-493-5p/Rab27A axis in ulcerative colitis.
Wang H, Teng J, Wang M, Zhang Y, Liu X, Liu Z., Free PMC Article | 05/31/2023 |
| [Silencing RAB27a inhibits proliferation, invasion and adhesion of triple-negative breast cancer cells]. | [Silencing RAB27a inhibits proliferation, invasion and adhesion of triple-negative breast cancer cells].
Wang L, Yan Z, Xia Y., Free PMC Article | 05/23/2023 |
| Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding. | Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding.
Zondag TCE, Torralba-Raga L, Van Laar JAM, Hermans MAW, Bouman A, Hollink IHIM, Van Hagen PM, Briggs DA, Hume AN, Bryceson YT., Free PMC Article | 01/28/2023 |
| RAB27A promotes the proliferation and invasion of colorectal cancer cells. | RAB27A promotes the proliferation and invasion of colorectal cancer cells.
Li Q, Zhao H, Dong W, Guan N, Hu Y, Zeng Z, Zhang H, Zhang F, Li Q, Yang J, Xiao W., Free PMC Article | 11/19/2022 |
| PRR34-AS1 promotes exosome secretion of VEGF and TGF-beta via recruiting DDX3X to stabilize Rab27a mRNA in hepatocellular carcinoma. | PRR34-AS1 promotes exosome secretion of VEGF and TGF-β via recruiting DDX3X to stabilize Rab27a mRNA in hepatocellular carcinoma.
Zhang Z, Zhou Y, Jia Y, Wang C, Zhang M, Xu Z., Free PMC Article | 11/5/2022 |
| Exosomal expression of RAB27A and its related lncRNA Lnc-RNA-RP11-510M2 in lung cancer. | Exosomal expression of RAB27A and its related lncRNA Lnc-RNA-RP11-510M2 in lung cancer.
Mohamed Gamal El-Din G, Ibrahim FK, Shehata HH, Osman NM, Abdel-Rahman OM, Ali M. | 10/29/2022 |
| RAB27A and RAB27B Expression May Predict Lymph Node Metastasis and Survival in Patients With Gastric Cancer. | RAB27A and RAB27B Expression May Predict Lymph Node Metastasis and Survival in Patients With Gastric Cancer.
An HJ, Lee JS, Yang JW, Kim MH, Na JM, Song DH., Free PMC Article | 09/3/2022 |
| BMAL1 induces colorectal cancer metastasis by stimulating exosome secretion. | BMAL1 induces colorectal cancer metastasis by stimulating exosome secretion.
Dong P, Wang Y, Liu Y, Zhu C, Lin J, Qian R, Hua L, Lu C. | 03/26/2022 |
| GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies. | GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.
Kat M, Bürgisser PE, Janssen H, De Cuyper IM, Conte IL, Hume AN, Carter T, Voorberg J, Margadant C, Bierings R., Free PMC Article | 01/15/2022 |
| Abrogation of RAB27A expression transiently affects melanoma cell proliferation. | Abrogation of RAB27A expression transiently affects melanoma cell proliferation.
Guo D, Beaumont KA, Sharp DM, Lui GYL, Weninger W, Haass NK, Tikoo S. | 08/14/2021 |
| Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement. | Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement.
Ohishi Y, Ammann S, Ziaee V, Strege K, Groß M, Amos CV, Shahrooei M, Ashournia P, Razaghian A, Griffiths GM, Ehl S, Fukuda M, Parvaneh N., Free PMC Article | 06/26/2021 |
| A founder RAB27A variant causes Griscelli syndrome type 2 with phenotypic heterogeneity in Qatari families. | A founder RAB27A variant causes Griscelli syndrome type 2 with phenotypic heterogeneity in Qatari families.
Al-Sulaiman R, Othman A, El-Akouri K, Fareed S, AlMulla H, Sukik A, Al-Mureikhi M, Shahbeck N, Ali R, Al-Mesaifri F, Musa S, Al-Mulla M, Ibrahim K, Mohamed K, Al-Nesef MA, Ehlayel M, Ben-Omran T. | 06/19/2021 |
| Rab27A promotes cellular apoptosis and ROS production by regulating the miRNA-124-3p/STAT3/RelA signalling pathway in ulcerative colitis. | Rab27A promotes cellular apoptosis and ROS production by regulating the miRNA-124-3p/STAT3/RelA signalling pathway in ulcerative colitis.
Luo Y, Yu MH, Yan YR, Zhou Y, Qin SL, Huang YZ, Qin J, Zhong M., Free PMC Article | 05/8/2021 |
| Rab27a dependent exosome releasing participated in albumin handling as a coordinated approach to lysosome in kidney disease. | Rab27a dependent exosome releasing participated in albumin handling as a coordinated approach to lysosome in kidney disease.
Feng Y, Zhong X, Tang TT, Wang C, Wang LT, Li ZL, Ni HF, Wang B, Wu M, Liu D, Liu H, Tang RN, Liu BC, Lv LL., Free PMC Article | 03/27/2021 |
| RAB27A/Melanophilin Blocker Inhibits Melanoma Cell Motility and Invasion. | RAB27A/Melanophilin Blocker Inhibits Melanoma Cell Motility and Invasion.
Guo D, Jain R, Hwang JS, Weninger W, Beaumont KA, Tikoo S. | 03/6/2021 |
| Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth. | Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth.
Ku KE, Choi N, Sung JH., Free PMC Article | 02/20/2021 |
| Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins. | Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins.
Alzahofi N, Welz T, Robinson CL, Page EL, Briggs DA, Stainthorp AK, Reekes J, Elbe DA, Straub F, Kallemeijn WW, Tate EW, Goff PS, Sviderskaya EV, Cantero M, Montoliu L, Nedelec F, Miles AK, Bailly M, Kerkhoff E, Hume AN., Free PMC Article | 09/5/2020 |
| Frameshift mutation in the RAB27A gene is associated with seizures and neurological compromise in patient 1 and pancytopenia and diarrhea in patient 2. | Griscelli Type 2 Syndrome and Hemophagocytic Lymphohistiocytosis: Sisters With the Same Mutation but Different Presentations.
Russ A, Mack J, Green-Murphy A, Occidental M, Mian A. | 04/18/2020 |
| TLR3 agonist Poly(I:C) increases RAB27 A mRNA and protein expression and enhances co-localization of RAB27 A and Gp100+melanosome at cell periphery in human melanocytes. Correlatively, the knockdown of RAB27 A decreases the melanosome transfer by Poly(I:C). Normal human epidermal melanocytes utilize common innate immune system to enhance melanogenesis and affect melanosome transfer to neighboring keratinocytes. | TRIF and MAVS signaling pathways regulate RAB27A induction and melanosome transfer by TLR3 signaling in human epidermal melanocytes.
Koike S, Yamasaki K, Yamauchi T, Shimada-Omori R, Tsuchiyama K, Aiba S. | 04/4/2020 |