Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization. | Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization. Wang J, Wang T, Feng YK, Liu Y, Fu B, Liu XT, Wu QZ. | 01/5/2024 |
RAB1A haploinsufficiency phenocopies the 2p14-p15 microdeletion and is associated with impaired neuronal differentiation. | RAB1A haploinsufficiency phenocopies the 2p14-p15 microdeletion and is associated with impaired neuronal differentiation. Rios JJ, Li Y, Paria N, Bohlender RJ, Huff C, Rosenfeld JA, Liu P, Bi W, Haga K, Fukuda M, Vashisth S, Kaur K, Chahrour MH, Bober MB, Duker AL, Ladha FA, Hanchard NA, Atala K, Khanshour AM, Smith L, Wise CA, Delgado MR., Free PMC Article | 12/21/2023 |
Prognosis value and positive association of Rab1A/IL4Ralpha aberrant expression in gastric cancer. | Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer. Li H, Cheng Z, Jiang B, Shao X, Xu M., Free PMC Article | 05/3/2023 |
Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release. | Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release. Chao TY, Cheng YY, Wang ZY, Fang TF, Chang YR, Fuh CS, Su MT, Su YW, Hsu PH, Su YC, Chang YC, Lee TY, Chou WH, Middeldorp JM, Saraste J, Chen MR., Free PMC Article | 02/27/2023 |
SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination. | SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination. Lv T, He D, Zhang X, Guo X, Li Z, Zhang A, Fan B, Wang Z., Free PMC Article | 01/14/2023 |
Circ_0061140 Contributes to the Malignant Progression in Ovarian Cancer Cells by Mediating the RAB1A Level Through Sponging miR-361-5p. | Circ_0061140 Contributes to the Malignant Progression in Ovarian Cancer Cells by Mediating the RAB1A Level Through Sponging miR-361-5p. Zhang Y, Di Q, Chen J, Chang M, Ma Y, Yu J. | 11/5/2022 |
Circ_0026123 promotes cisplatin resistance and progression of ovarian cancer by upregulating RAB1A through sequestering miR-543. | Circ_0026123 promotes cisplatin resistance and progression of ovarian cancer by upregulating RAB1A through sequestering miR-543. Wei L, He W, Zhao H, Zhao P. | 10/22/2022 |
Differences in IFNbeta secretion upon Rab1 inactivation in cells exposed to distinct innate immune stimuli. | Differences in IFNβ secretion upon Rab1 inactivation in cells exposed to distinct innate immune stimuli. Yang J, Zhou X, Zhang R, Sun H, You F, Jiang Z., Free PMC Article | 01/29/2022 |
Rab1A promotes IL-4R/JAK1/STAT6-dependent metastasis and determines JAK1 inhibitor sensitivity in non-small cell lung cancer. | Rab1A promotes IL-4R/JAK1/STAT6-dependent metastasis and determines JAK1 inhibitor sensitivity in non-small cell lung cancer. Huang T, Chen B, Wang F, Cai W, Wang X, Huang B, Liu F, Jiang B, Zhang Y. | 01/8/2022 |
RAB1A regulates glioma cellular proliferation and invasion via the mTOR signaling pathway and epithelial-mesenchymal transition. | RAB1A regulates glioma cellular proliferation and invasion via the mTOR signaling pathway and epithelial-mesenchymal transition. Ren B, Wang L, Nan Y, Liu T, Zhao L, Ma H, Li J, Zhang Y, Ren X. | 12/25/2021 |
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer. | Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer. Peng C, Li X, Ye Z, Wu W., Free PMC Article | 11/13/2021 |
Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A. | Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A. Xiong B, Huang J, Liu Y, Zou M, Zhao Z, Gong J, Wu X, Qiu C. | 10/9/2021 |
Clinical value and potential association of Rab1A and FoxM1 aberrant expression in colorectal cancer. | Clinical value and potential association of Rab1A and FoxM1 aberrant expression in colorectal cancer. Xu M, Shao X, Li H, Zhang Z, Zhou C, Cheng Z., Free PMC Article | 04/24/2021 |
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes. | Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes. Tremel S, Ohashi Y, Morado DR, Bertram J, Perisic O, Brandt LTL, von Wrisberg MK, Chen ZA, Maslen SL, Kovtun O, Skehel M, Rappsilber J, Lang K, Munro S, Briggs JAG, Williams RL., Free PMC Article | 04/13/2021 |
MiR-1202 Exerts Neuroprotective Effects on OGD/R Induced Inflammation in HM Cell by Negatively Regulating Rab1a Involved in TLR4/NF-kappaB Signaling Pathway. | MiR-1202 Exerts Neuroprotective Effects on OGD/R Induced Inflammation in HM Cell by Negatively Regulating Rab1a Involved in TLR4/NF-κB Signaling Pathway. Song S, Pan Y, Li H, Zhen H. | 02/2/2021 |
Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy. | Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy. Toh H, Nozawa T, Minowa-Nozawa A, Hikichi M, Nakajima S, Aikawa C, Nakagawa I., Free PMC Article | 11/28/2020 |
Expression analysis and implication of Rab1A in gastrointestinal relevant tumor. | Expression analysis and implication of Rab1A in gastrointestinal relevant tumor. Xu M, Shao X, Kuai X, Zhang L, Zhou C, Cheng Z., Free PMC Article | 11/21/2020 |
MiR-655-3p inhibited proliferation and migration of ovarian cancer cells by targeting RAB1A. | MiR-655-3p inhibited proliferation and migration of ovarian cancer cells by targeting RAB1A. Zha JF, Chen DX. | 09/19/2020 |
Knockdown of Rab1A protein represses proliferation and promotes apoptosis in gastric cancer cells by inhibition of the mTOR/p70S6K pathway. | Rab1A knockdown represses proliferation and promotes apoptosis in gastric cancer cells by inhibition of mTOR/p70S6K pathway. Li Z, Li Y, Jia Y, Ding B, Yu J. | 07/18/2020 |
The circ_0000218 upregulated RAB1A and promoted colorectal cancer (CRC) proliferation and metastasis via sponging miR-139-3p. | Circ_0000218 plays a carcinogenic role in colorectal cancer progression by regulating miR-139-3p/RAB1A axis. Pei FL, Cao MZ, Li YF. | 03/28/2020 |
Result showed that the expression level of RAB1A was significantly increased in breast cancer (BC) tissues. Data indicate that RAB1A is a direct target gene of miR139 and plays an important role in miR139induced cell migration, invasion and epithelial-mesenchymal transformation in BC cells. | miR‑139‑3p suppresses the invasion and migration properties of breast cancer cells by targeting RAB1A. Zhang W, Xu J, Wang K, Tang X, He J., Free PMC Article | 03/28/2020 |
A systematic review and meta-analysis demonstrated that the expression of Rab1A is related with tumor size, differentiation, lymph node metastasis, TNM stage. In addition, overexpression of Rab1A also leads to a poorer prognosis. | Pooled analysis of prognostic value and clinical significance of Rab1A expression in human solid tumors. Shao X, Cheng Z, Xu M, Tan Z, Gao L, Wang J, Zhou C., Free PMC Article | 02/1/2020 |
Study revealed that RAB1A is overexpressed in colorectal cancer (CRC) tissues compared with matched noncancerous tissues. High RAB1A expression was significantly associated with the TNM stage, lymph node metastasis, peritoneal metastasis, and significantly worse survival time than those with low RAB1A expression, which especially affected the survival in CRC patients with advanced stage. | Aberrant expression of Rab1A and its prognostic significance in human colorectal cancer. Wang ZK, Cheng ZW, Chen SJ, Zhu XG, Gu YP, Yang XD, Sun L, Liu WT, Zhang YJ, Yuan JF, Tian KJ, Yao YZ, He SB. | 12/14/2019 |
this study shows that Rab1 is required for NLRP3 inflammasome activation and inflammatory lung injury | The GTPase Rab1 Is Required for NLRP3 Inflammasome Activation and Inflammatory Lung Injury. Zhang Y, Wang L, Lv Y, Jiang C, Wu G, Dull RO, Minshall RD, Malik AB, Hu G., Free PMC Article | 11/9/2019 |
The subcellular localization of Rab1 is highly dynamic with a continuous flux between the cytoplasm and the Golgi compartment. | Spatial Cycling of Rab GTPase, Driven by the GTPase Cycle, Controls Rab's Subcellular Distribution. Voss S, Li F, Rätz A, Röger M, Wu YW. | 09/28/2019 |