| Claudin-10 Expression and the Gene Expression Pattern of Thick Ascending Limb Cells. | Claudin-10 Expression and the Gene Expression Pattern of Thick Ascending Limb Cells.
Brideau G, Cheval L, Griveau C, Ling WE, Lievre L, Crambert G, Müller D, Broćić J, Cherchame E, Houillier P, Prot-Bertoye C., Free PMC Article | 05/13/2024 |
| Unrecognized role of claudin-10b in basolateral membrane infoldings of the thick ascending limb. | Unrecognized role of claudin-10b in basolateral membrane infoldings of the thick ascending limb.
Quintanova C, Himmerkus N, Svendsen SL, von Schwerdtner O, Merkel C, Pinckert L, Mutig K, Breiderhoff T, Müller D, Günzel D, Bleich M. | 11/26/2022 |
| Claudin-10a Deficiency Shifts Proximal Tubular Cl(-) Permeability to Cation Selectivity via Claudin-2 Redistribution. | Claudin-10a Deficiency Shifts Proximal Tubular Cl(-) Permeability to Cation Selectivity via Claudin-2 Redistribution.
Breiderhoff T, Himmerkus N, Meoli L, Fromm A, Sewerin S, Kriuchkova N, Nagel O, Ladilov Y, Krug SM, Quintanova C, Stumpp M, Garbe-Schönberg D, Westernströer U, Merkel C, Brinkhus MA, Altmüller J, Schweiger MR, Müller D, Mutig K, Morawski M, Halbritter J, Milatz S, Bleich M, Günzel D., Free PMC Article | 04/9/2022 |
| Severe individual renal phenotypes in claudin-10 and claudin-16 knockout mice are corrected by the additional deletion of the other claudin. | Deletion of claudin-10 rescues claudin-16-deficient mice from hypomagnesemia and hypercalciuria.
Breiderhoff T, Himmerkus N, Drewell H, Plain A, Günzel D, Mutig K, Willnow TE, Müller D, Bleich M. | 12/22/2018 |
| ConclusionCLDN10 mutations cause a dysfunction in TJs in several tissues and, subsequently, abnormalities in renal ion transport, ectodermal gland homeostasis, and epidermal integrity. | Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX syndrome.
Hadj-Rabia S, Brideau G, Al-Sarraj Y, Maroun RC, Figueres ML, Leclerc-Mercier S, Olinger E, Baron S, Chaussain C, Nochy D, Taha RZ, Knebelmann B, Joshi V, Curmi PA, Kambouris M, Vargas-Poussou R, Bodemer C, Devuyst O, Houillier P, El-Shanti H. | 09/29/2018 |
| findings suggest that the axis IL-10/claudin-10 is a promising target for the development of therapeutic agents against aggressive melanoma | The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes.
Perez EC, Xander P, Laurindo MFL, Novaes E Brito RR, Vivanco BC, Mortara RA, Mariano M, Lopes JD, Keller AC., Free PMC Article | 12/30/2017 |
| localization of Cldn3, Cldn7 and Cldn10 proteins in the different compartments of murine endometrium up to day 8.5 of pregnancy (dpc) as well as in human endometrium and first trimester decidua | Claudin-3, claudin-7, and claudin-10 show different distribution patterns during decidualization and trophoblast invasion in mouse and human.
Schumann S, Buck VU, Classen-Linke I, Wennemuth G, Grümmer R. | 09/3/2016 |
| These data identify claudin-10 as a key factor in control of cation selectivity and transport in the thick ascending limb, and deficiency in this pathway as a cause of nephrocalcinosis. | Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis.
Breiderhoff T, Himmerkus N, Stuiver M, Mutig K, Will C, Meij IC, Bachmann S, Bleich M, Willnow TE, Müller D., Free PMC Article | 12/22/2012 |
| Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function. | Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function.
Günzel D, Stuiver M, Kausalya PJ, Haisch L, Krug SM, Rosenthal R, Meij IC, Hunziker W, Fromm M, Müller D. | 01/21/2010 |
| alternative splicing of claudin-10 generates unique permselectivities and might contribute to the variable paracellular transport observed along the nephron | Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities.
Van Itallie CM, Rogan S, Yu A, Vidal LS, Holmes J, Anderson JM. | 01/21/2010 |
| Claudin-10 is expressed at the variety of epithelial tissues in the coclea of inner ear including Organ of Corti, stria vascularis, Reissner's membrane, and spiral limbus. | Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.
Kitajiri SI, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita S. | 12/5/2012 |