| Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway. | Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway.
Peng C, Zhang C, Yu W, Li L, Zhang Z, Liu T, Zhang Y, Fan G, Huangfu H. | 06/2/2023 |
| RPTPepsilon promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation. | RPTPε promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation.
Lapointe F, Turcotte S, Roy J, Bissonnette E, Rola-Pleszczynski M, Stankova J. | 06/26/2021 |
| these data demonstrate that HCV infection reduces PTPRE expression in the liver and peripheral blood mononuclear cell sof infected humans | Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo.
Bhattarai N, McLinden JH, Xiang J, Mathahs MM, Schmidt WN, Kaufman TM, Stapleton JT., Free PMC Article | 08/5/2017 |
| Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells. | Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells.
Nunes-Xavier CE, Elson A, Pulido R., Free PMC Article | 03/24/2012 |
| Studies indicate that RAD50 and PTPRE of crude associations with asthma at a Bonferroni-corrected level of significance, while IL4R, CCL5 and TBXA2R of nominal significance. | Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.
Murk W, Walsh K, Hsu LI, Zhao L, Bracken MB, Dewan AT. | 01/28/2012 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Human variation in alcohol response is influenced by variation in neuronal signaling genes.
Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL. | 04/7/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenes to diseases (G2D) computational method to identify asthma candidate genes.
Tremblay K, Lemire M, Potvin C, Tremblay A, Hunninghake GM, Raby BA, Hudson TJ, Perez-Iratxeta C, Andrade-Navarro MA, Laprise C. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. | 08/20/2008 |
| Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling | Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling.
Kraut-Cohen J, Muller WJ, Elson A. | 01/21/2010 |
| cyt-PTP epsilon is dimerized and phosphorylated in the absence of direct interaction between the PTP and extracellular molecules | Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon.
Toledano-Katchalski H, Tiran Z, Sines T, Shani G, Granot-Attas S, den Hertog J, Elson A., Free PMC Article | 01/21/2010 |
| Characterization, expression and functional aspects of an alternative spliced isoform of protein tyrosine phosphatase epsilon | Characterization, expression and functional aspects of a novel protein tyrosine phosphatase epsilon isoform.
Wabakken T, Hauge H, Funderud S, Aasheim HC. | 01/21/2010 |
| interactions between RPTP-domain1s and RPTP-domain 2s are a common but specific mechanism that is likely to be regulated- domain2s and the wedge structures are crucial determinants of binding specificity, thus regulating cross-talk between RPTPs | Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.
Blanchetot C, Tertoolen LG, Overvoorde J, den Hertog J. | 01/21/2010 |
| Transfection of cells with different PTPepsilon constructs and activator protein-1 reporter gene indicates that the catalytic activity of PTPepsilon is involved in the regulation of the mitogen-activated protein kinase cascade. | Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase.
Wabakken T, Hauge H, Finne EF, Wiedlocha A, Aasheim H. | 01/21/2010 |
| Transgenic mice overexpressing catalytically inactive transmembrane protein tyrosine phosphatase epsilon provide unexpected insight into the cell-cell interactions that occur between oligodendrocytes and the cells which they myelinate. | Expression of a catalytically inactive transmembrane protein tyrosine phosphatase epsilon (tm-PTP epsilon) delays optic nerve myelination.
Muja N, Lovas G, Romm E, Machleder D, Ranjan M, Gallo V, Hudson LD. | 01/21/2010 |
| Functions to prevent inappropriate activation and to terminate prolonged, rather than acute, activation of ERK in the cytosol. | Protein tyrosine phosphatase epsilon inhibits signaling by mitogen-activated protein kinases.
Toledano-Katchalski H, Kraut J, Sines T, Granot-Attas S, Shohat G, Gil-Henn H, Yung Y, Elson A. | 01/21/2010 |