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    PTPRC protein tyrosine phosphatase receptor type C [ Homo sapiens (human) ]

    Gene ID: 5788, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.

    Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.
    Yang C, Wang X, To KKW, Cui C, Luo M, Wu S, Huang L, Fu K, Pan C, Liu Z, Fan T, Yang C, Wang F, Fu L., Free PMC Article

    04/12/2024
    Implications of CD45RA and CD45RO T cell subsets in patients of chronic rhinosinusitis with nasal polyposis infected with Aspergillus flavus.

    Implications of CD45RA and CD45RO T cell subsets in patients of chronic rhinosinusitis with nasal polyposis infected with Aspergillus flavus.
    Rai G, Das S, Ansari MA, Singh PK, Dar SA, Gupta N, Sharma S, Ramachandran VG, Jain C.

    03/6/2024
    [CD45 pre-exclusion from the tips of microvilli : role in their activation].

    [CD45 pre-exclusion from the tips of microvilli : role in their activation].
    Lafargue-Hauret J, Lozac'h K, Kabore B, Bobé P.

    02/28/2024
    Frequent expression of CD45RO memory T cell marker as well as low to high expression of PD-1 and PD-L1 inhibitory molecules in seminoma and dysgerminoma.

    Frequent expression of CD45RO memory T cell marker as well as low to high expression of PD-1 and PD-L1 inhibitory molecules in seminoma and dysgerminoma.
    Farahani H, Dehghanian AR, Khademolhosseini A, Haghshenas MR, Erfani N.

    02/6/2024
    Plasma-derived extracellular vesicle surface markers CD45, CD326 and CD56 correlate with the stage of osteoarthritis: a primary study of a novel and promising diagnostic tool of the disease.

    Plasma-derived extracellular vesicle surface markers CD45, CD326 and CD56 correlate with the stage of osteoarthritis: a primary study of a novel and promising diagnostic tool of the disease.
    Matejova J, Fecskeova LK, Slovinska L, Harvanova D, Spakova T, Bzdilova J., Free PMC Article

    11/28/2023
    PTPRC functions as a prognosis biomarker in the tumor microenvironment of cutaneous melanoma.

    PTPRC functions as a prognosis biomarker in the tumor microenvironment of cutaneous melanoma.
    Li X, Yue Z, Wang D, Zhou L., Free PMC Article

    11/28/2023
    CD45[-] erythroid progenitor cells promote lymph node metastasis in gastric cancer by inducing a hybrid epithelial/mesenchymal state in lymphatic endothelial cells.

    CD45(-) erythroid progenitor cells promote lymph node metastasis in gastric cancer by inducing a hybrid epithelial/mesenchymal state in lymphatic endothelial cells.
    Wen JY, Li X, Chen JN, Chen J, Zhang JY, Du Y, Zhu WH, Chen YJ, Yang RH, Shao CK.

    11/14/2023
    Eosinophilic allergic rhinitis is strongly associated with the CD45RB[lo] subset of CD161[+] Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13.

    Eosinophilic allergic rhinitis is strongly associated with the CD45RB(lo) subset of CD161(+) Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13.
    Lee WWL, Puan KJ, Lee B, Chua C, Koh SM, Yusof N, Tan KP, Luis BS, Ong J, Merid SK, Ang R, Chan XY, Hui LJ, Terenzani E, Lum J, Foo S, Zolezzi F, Yan ATS, Melen E, Yi SJ, Rotzschke O, Andiappan AK.

    10/10/2023
    CD45RA and CD45RO Are Regulated in a Cell-Type Specific Manner in Inflammation and Sepsis.

    CD45RA and CD45RO Are Regulated in a Cell-Type Specific Manner in Inflammation and Sepsis.
    Ahmed MGT, Limmer A, Hartmann M., Free PMC Article

    08/2/2023
    CD45 Is Sufficient to Initiate Endothelial-to-Mesenchymal Transition in Human Endothelial Cells-Brief Report.

    CD45 Is Sufficient to Initiate Endothelial-to-Mesenchymal Transition in Human Endothelial Cells-Brief Report.
    Nasim S, Wylie-Sears J, Gao X, Peng Q, Zhu B, Chen K, Chen H, Bischoff J., Free PMC Article

    05/15/2023
    Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection.

    Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection.
    Li Y, Lefebvre F, Nakku-Joloba E, Ronald A, Gray G, de Bruyn G, Kiarie J, Celum C, Cameron MJ, Lingappa JR, Mackelprang RD., Free PMC Article

    03/7/2023
    PTPRC Overexpression Predicts Poor Prognosis and Correlates with Immune Cell Infiltration in Pediatric Acute Myeloid Leukemia.

    PTPRC Overexpression Predicts Poor Prognosis and Correlates with Immune Cell Infiltration in Pediatric Acute Myeloid Leukemia.
    Guo G, Li B, Li Q, Li C, Guo D.

    08/27/2022
    Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient.

    Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient.
    Gebremicael G, Gebreegziabxier A, Kassa D., Free PMC Article

    06/25/2022
    The aberrant expression of CD45 isoforms and levels of sex hormones in systemic lupus erythematosus.

    The aberrant expression of CD45 isoforms and levels of sex hormones in systemic lupus erythematosus.
    Dong Z, Zhang B, Rong J, Yang X, Wang Y, Zhang Q, Su Z.

    03/26/2022
    Characteristic CD45RA/CD45RO maturation pattern by flow cytometry associated with the CD45 C77G polymorphism.

    Characteristic CD45RA/CD45RO maturation pattern by flow cytometry associated with the CD45 C77G polymorphism.
    Courville EL, Lawrence MG.

    02/12/2022
    Exploring blast composition in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms: CD45RA and CD371 improve diagnostic value of flow cytometry through assessment of myeloblast heterogeneity and stem cell aberrancy.

    Exploring blast composition in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms: CD45RA and CD371 improve diagnostic value of flow cytometry through assessment of myeloblast heterogeneity and stem cell aberrancy.
    Shameli A, Dharmani-Khan P, Luider J, Auer I, Shabani-Rad MT., Free PMC Article

    02/12/2022
    The soluble cytoplasmic tail of CD45 regulates T-cell activation via TLR4 signaling.

    The soluble cytoplasmic tail of CD45 regulates T-cell activation via TLR4 signaling.
    Puck A, Künig S, Modak M, May L, Fritz P, Battin C, Radakovics K, Steinberger P, Reipert BM, Crowe BA, Stöckl J.

    02/12/2022
    Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cells.

    Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cells.
    Park SY, Kim JY, Jang GB, Choi JH, Kim JH, Lee CJ, Lee S, Baek JH, Park KK, Kim JM, Chang HJ, Cho NC, Nam JS., Free PMC Article

    02/5/2022
    Identification of 4-methylation driven genes based prognostic signature in thyroid cancer: an integrative analysis based on the methylmix algorithm.

    Identification of 4-methylation driven genes based prognostic signature in thyroid cancer: an integrative analysis based on the methylmix algorithm.
    Chen Z, Liu X, Liu F, Zhang G, Tu H, Lin W, Lin H., Free PMC Article

    01/22/2022
    High-purity Isolation for Genotyping Rare Cancer Cells from Blood Using a Microfluidic Chip Cell Sorter.

    High-purity Isolation for Genotyping Rare Cancer Cells from Blood Using a Microfluidic Chip Cell Sorter.
    Ikeda M, Koh Y, Oyanagi J, Teraoka S, Ishige M, Fujimura Y, Takeda K, Tokudome N, Ozawa Y, Ueda H, Yamamoto N.

    01/15/2022
    CD45-negative follicular lymphoma: A rare diagnostic pitfall of a common entity.

    CD45-negative follicular lymphoma: A rare diagnostic pitfall of a common entity.
    Khanlari M, Wang SA, Tang G, Saluja K, Medeiros LJ, Thakral B.

    01/8/2022
    The Potential Role of Protein Tyrosine Phosphatase, Receptor Type C (CD45) in the Intestinal Ischemia-Reperfusion Injury.

    The Potential Role of Protein Tyrosine Phosphatase, Receptor Type C (CD45) in the Intestinal Ischemia-Reperfusion Injury.
    Cong R, Yang J, Zhou J, Shi J, Zhu Y, Zhu J, Xiao J, Wang P, He Y, He B.

    10/9/2021
    Prognostic Value of CD45Ro(+) T-Cell Expression in Patients With Oral Squamous Cell Carcinoma.

    Prognostic Value of CD45Ro(+) T-Cell Expression in Patients With Oral Squamous Cell Carcinoma.
    Koike K, Nishiyama K, Dehari H, Ogi K, Sasaki T, Shimizu S, Sasaya T, Tsuchihashi K, Sonoda T, Hasegawa T, Hiratsuka H, Miyazaki A.

    09/11/2021
    Natural Antisense Transcript PEBP1P3 Regulates the RNA Expression, DNA Methylation and Histone Modification of CD45 Gene.

    Natural Antisense Transcript PEBP1P3 Regulates the RNA Expression, DNA Methylation and Histone Modification of CD45 Gene.
    Su Z, Liu G, Zhang B, Lin Z, Huang D., Free PMC Article

    08/28/2021
    Prognostic significance of CD45 antigen expression in pediatric acute lymphoblastic leukemia.

    Prognostic significance of CD45 antigen expression in pediatric acute lymphoblastic leukemia.
    Balasubramanian P, Singh J, Verma D, Kumar R, Bakhshi S, Tanwar P, Singh AR, Chopra A.

    08/14/2021
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