| PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the beta5 integrin. | PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
Datta R, Mukherjee D, Podolsky MJ, Yang CD, Alba DL, Singh S, Arnold TD, Koliwad S, Lizama CO, Atabai K., Free PMC Article | 02/27/2024 |
| High-resolution double vision of the allosteric phosphatase PTP1B. | High-resolution double vision of the allosteric phosphatase PTP1B.
Sharma S, Skaist Mehlman T, Sagabala RS, Boivin B, Keedy DA., Free PMC Article | 01/16/2024 |
| Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte. | Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte.
Hsu MF, Ito Y, Singh JP, Hsu SF, Wells A, Jen KY, Meng TC, Haj FG., | 11/20/2023 |
| Association between PTPN1 polymorphisms and obesity-related phenotypes in European adolescents: influence of physical activity. | Association between PTPN1 polymorphisms and obesity-related phenotypes in European adolescents: influence of physical activity.
Salazar-Tortosa DF, Labayen I, González-Gross M, Seral-Cortes M, Moreno LA, G Zapico A, Widhalm K, Meirhaeghe A, Enard D, R Ruiz J. | 07/12/2023 |
| A Conserved Local Structural Motif Controls the Kinetics of PTP1B Catalysis. | A Conserved Local Structural Motif Controls the Kinetics of PTP1B Catalysis.
Yeh CY, Izaguirre JA, Greisman JB, Willmore L, Maragakis P, Shaw DE., Free PMC Article | 07/12/2023 |
| PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension. | PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension.
Ali MK, Tian X, Zhao L, Schimmel K, Rhodes CJ, Wilkins MR, Nicolls MR, Spiekerkoetter EF., Free PMC Article | 02/11/2023 |
| Computational analysis of PTP-1B site-directed mutations and their structural binding to potential inhibitors. | Computational analysis of PTP-1B site-directed mutations and their structural binding to potential inhibitors.
Tasleem M, Shoaib A, Al-Shammary A, Abdelgadir A, Alsamar Z, Jamal QMS, Alrehaily A, Bardcki F, Sulieman AME, Upadhyay TK, Ansari IA, Lai D, Badroui R, Yadav DK, Saeed M. | 12/17/2022 |
| The role of PTP1B (PTPN1) in the prognosis of solid tumors: A meta-analysis. | The role of PTP1B (PTPN1) in the prognosis of solid tumors: A meta-analysis.
Zhou J, Guo H, Zhang Y, Liu H, Dou Q., Free PMC Article | 10/15/2022 |
| Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma. | Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma.
Liu R, Sun Y, Berthelet J, Bui LC, Xu X, Viguier M, Dupret JM, Deshayes F, Rodrigues Lima F., Free PMC Article | 07/16/2022 |
| ETS proto-oncogene 1 modulates PTP1B expression to participate in high glucose-mediated endothelial inflammation. | ETS proto-oncogene 1 modulates PTP1B expression to participate in high glucose-mediated endothelial inflammation.
Jiang L, Liang J, Wang T, Meng F, Duan W., Free PMC Article | 05/28/2022 |
| Rapid degradation of protein tyrosine phosphatase 1B in sickle cells: Possible contribution to sickle cell membrane weakening. | Rapid degradation of protein tyrosine phosphatase 1B in sickle cells: Possible contribution to sickle cell membrane weakening.
Noomuna P, Hausman JM, Sansoya R, Kalfa T, Risinger M, Low PS., Free PMC Article | 05/28/2022 |
| PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity. | PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity.
Wiede F, Lu KH, Du X, Zeissig MN, Xu R, Goh PK, Xirouchaki CE, Hogarth SJ, Greatorex S, Sek K, Daly RJ, Beavis PA, Darcy PK, Tonks NK, Tiganis T., Free PMC Article | 04/30/2022 |
| Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid. | Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid.
Qian L, Wang Q, Wei C, Wang L, Yang Y, Deng X, Liu J, Qi F. | 04/30/2022 |
| Targeting protein tyrosine phosphatase 1B in obesity-associated colon cancer: Possible role of sweet potato (Ipomoea batatas). | Targeting protein tyrosine phosphatase 1B in obesity-associated colon cancer: Possible role of sweet potato (Ipomoea batatas).
Sain A, Khamrai D, Kandasamy T, Naskar D. | 04/30/2022 |
| Structural Bases for Hesperetin Derivatives: Inhibition of Protein Tyrosine Phosphatase 1B, Kinetics Mechanism and Molecular Docking Study. | Structural Bases for Hesperetin Derivatives: Inhibition of Protein Tyrosine Phosphatase 1B, Kinetics Mechanism and Molecular Docking Study.
Ali MY, Jannat S, Jung HA, Choi JS., Free PMC Article | 02/19/2022 |
| Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation. | Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation.
Wang Q, Pan Y, Zhao L, Qi F, Liu J., Free PMC Article | 02/19/2022 |
| The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1. | The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1.
Singh JP, Li Y, Chen YY, Hsu SD, Page R, Peti W, Meng TC., Free PMC Article | 01/29/2022 |
| Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling. | Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling.
Schwarz JJ, Grundmann L, Kokot T, Kläsener K, Fotteler S, Medgyesi D, Köhn M, Reth M, Warscheid B., Free PMC Article | 01/29/2022 |
| The phosphatase PTPN1/PTP1B is a candidate marker of better chemotherapy response in metastatic high-grade serous carcinoma. | The phosphatase PTPN1/PTP1B is a candidate marker of better chemotherapy response in metastatic high-grade serous carcinoma.
Davidson B, Bock AJ, Holth A, Nymoen DA. | 12/25/2021 |
| Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation. | Curcumin and Its New Derivatives: Correlation between Cytotoxicity against Breast Cancer Cell Lines, Degradation of PTP1B Phosphatase and ROS Generation.
Kostrzewa T, Wołosewicz K, Jamrozik M, Drzeżdżon J, Siemińska J, Jacewicz D, Górska-Ponikowska M, Kołaczkowski M, Łaźny R, Kuban-Jankowska A., Free PMC Article | 10/30/2021 |
| The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy. | The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.
Huang T, Li X, Wang F, Lu L, Hou W, Zhu M, Miao C., Free PMC Article | 10/16/2021 |
| The PTP1B mutant PTP1B2-4 is a positive regulator of the JAK/STAT signalling pathway in Hodgkin lymphoma. | The PTP1B mutant PTP1B∆2-4 is a positive regulator of the JAK/STAT signalling pathway in Hodgkin lymphoma.
Zahn M, Kaluszniak B, Möller P, Marienfeld R., Free PMC Article | 10/2/2021 |
| Indole- and Pyrazole-Glycyrrhetinic Acid Derivatives as PTP1B Inhibitors: Synthesis, In Vitro and In Silico Studies. | Indole- and Pyrazole-Glycyrrhetinic Acid Derivatives as PTP1B Inhibitors: Synthesis, In Vitro and In Silico Studies.
De-la-Cruz-Martínez L, Duran-Becerra C, González-Andrade M, Páez-Franco JC, Germán-Acacio JM, Espinosa-Chávez J, Torres-Valencia JM, Pérez-Villanueva J, Palacios-Espinosa JF, Soria-Arteche O, Cortés-Benítez F., Free PMC Article | 09/18/2021 |
| Activation of PTP1B/EGFR signaling and cytotoxicity during combined exposure to ambient electrophiles in A431 cells. | Activation of PTP1B/EGFR signaling and cytotoxicity during combined exposure to ambient electrophiles in A431 cells.
Abiko Y, Kurosawa K, Yamakawa H, Kumagai Y. | 09/11/2021 |
| Pyrazoles as novel protein tyrosine phosphatase 1B (PTP1B) inhibitors: An in vitro and in silico study. | Pyrazoles as novel protein tyrosine phosphatase 1B (PTP1B) inhibitors: An in vitro and in silico study.
Rocha S, Lucas M, Silva VLM, Gomes PMO, Silva AMS, Araújo AN, Aniceto N, Guedes RC, Corvo ML, Fernandes E, Freitas M. | 07/24/2021 |