| USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast. | USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Yan J, Gu X, Gao X, Shao Y, Ji M., Free PMC Article | 08/22/2024 |
| USP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells. | USP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells.
Gao B, Qiao Y, Zhu S, Yang N, Zou SS, Liu YJ, Chen J., Free PMC Article | 07/25/2024 |
| Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non-Small Cell Lung Cancer. | Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non-Small Cell Lung Cancer.
Guan S, Chen X, Wei Y, Wang F, Xie W, Chen Y, Liang H, Zhu X, Yang Y, Fang W, Huang Y, Zhao H, Zhang X, Liu S, Zhuang W, Huang M, Wang X, Zhang L. | 04/8/2024 |
| USP36 plays an oncogenic role in colorectal cancer cells. | USP36 plays an oncogenic role in colorectal cancer cells.
Luo L, Li Y, Huang R, Li L, Wu C, Zeng Q. | 03/21/2024 |
| The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8. | The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8.
Li Y, Carey TS, Feng CH, Zhu HM, Sun XX, Dai MS., Free PMC Article | 08/9/2023 |
| The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing. | The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.
Chen Y, Li Y, Dai RS, Savage JC, Shinde U, Klimek J, David LL, Young EA, Hafner M, Sears RC, Sun XX, Dai MS., Free PMC Article | 05/11/2023 |
| USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP. | USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.
Zhang W, Luo J, Xiao Z, Zang Y, Li X, Zhou Y, Zhou J, Tian Z, Zhu J, Zhao X., Free PMC Article | 12/17/2022 |
| CircRNA circUSP36 impairs the stability of NEDD4L mRNA through recruiting PTBP1 to enhance ULK1-mediated autophagic granulosa cell death. | CircRNA circUSP36 impairs the stability of NEDD4L mRNA through recruiting PTBP1 to enhance ULK1-mediated autophagic granulosa cell death.
Zhou J, Zhou J, Wu LJ, Li YY, Li MQ, Liao HQ. | 10/8/2022 |
| DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer. | DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer.
Wang D, Li Z, Li X, Yan C, Yang H, Zhuang T, Wang X, Zang Y, Liu Z, Wang T, Jiang R, Su P, Zhu J, Ding Y., Free PMC Article | 07/23/2022 |
| Gene Signature and Prognostic Value of Ubiquitin-Specific Proteases Members in Hepatocellular Carcinoma and Explored the Immunological Role of USP36. | Gene Signature and Prognostic Value of Ubiquitin-Specific Proteases Members in Hepatocellular Carcinoma and Explored the Immunological Role of USP36.
Sun W, Shen J, Liu J, Han K, Liang L, Gao Y. | 07/2/2022 |
| USP36 promotes tumor growth of non-small cell lung cancer via increasing KHK-A expression by regulating c-MYC-hnRNPH1/H2 axis. | USP36 promotes tumor growth of non-small cell lung cancer via increasing KHK-A expression by regulating c-MYC-hnRNPH1/H2 axis.
Deng Q, Wu M, Deng J. | 03/5/2022 |
| Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36. | Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36.
van den Heuvel J, Ashiono C, Gillet LC, Dörner K, Wyler E, Zemp I, Kutay U., Free PMC Article | 11/13/2021 |
| The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis. | The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis.
Ryu H, Sun XX, Chen Y, Li Y, Wang X, Dai RS, Zhu HM, Klimek J, David L, Fedorov LM, Azuma Y, Sears RC, Dai MS., Free PMC Article | 08/21/2021 |
| The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization. | The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z., Free PMC Article | 01/16/2021 |
| USP36 as regulator for the Parkin-dependent mitophagy at least in part via the Beclin-1-ATG14L pathway. | Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L.
Geisler S, Jäger L, Golombek S, Nakanishi E, Hans F, Casadei N, Terradas AL, Linnemann C, Kahle PJ. | 06/20/2020 |
| USP36 overexpression decreased ischemia-induced apoptosis and oxidative stress in human renal tubular HK-2cells. The protein levels of c-Myc and SOD2 were declined in ischemic HK-2cells with enhanced ubiquitination. USP36 overexpression stabilized c-Myc and SOD2 by preventing ischemia-induced ubiquitination of both proteins. | USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
Liu Q, Sheng W, Ma Y, Zhen J, Roy S, Alvira Jafar C, Xin W, Wan Q. | 05/2/2020 |
| USP36 regulates PME-1 as a DUB and participates in the ERK and Akt signaling pathways | PME-1 is regulated by USP36 in ERK and Akt signaling pathways.
Kim SY, Choi J, Lee DH, Park JH, Hwang YJ, Baek KH. | 03/2/2019 |
| Together, our results reveal USP36 as a novel H2B deubiquitinase and shed light on its additional functions in regulating gene expression. | The ubiquitin-specific protease USP36 is a conserved histone H2B deubiquitinase.
DeVine T, Sears RC, Dai MS., Free PMC Article | 02/17/2018 |
| USP36 actions extend beyond TrkA because the presence of USP36 interferes with Nedd4-2-dependent Kv7.2/3 channel regulation. | Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).
Anta B, Martín-Rodríguez C, Gomis-Perez C, Calvo L, López-Benito S, Calderón-García AA, Vicente-García C, Villarroel Á, Arévalo JC., Free PMC Article | 05/13/2017 |
| USP36 is a crucial and bono fide deubiquitinating enzyme controlling c-Myc's nucleolar degradation pathway | The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc.
Sun XX, He X, Yin L, Komada M, Sears RC, Dai MS., Free PMC Article | 06/20/2015 |
| Recently, much progress has been made in understanding the physiological functions of cytokine-inducible DUBs such as DUB-1, DUB-2, and DUB-3/USP17, in regulation of cell proliferation and apoptosis in lymphocytes. [review] | Molecular mechanisms and functions of cytokine-inducible deubiquitinating enzymes.
Lim KH, Ramakrishna S, Baek KH. | 04/26/2014 |
| USP36 controls selective autophagy activation in Drosophila and in human cells. | The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins.
Taillebourg E, Gregoire I, Viargues P, Jacomin AC, Thevenon D, Faure M, Fauvarque MO. | 11/17/2012 |
| The most significantly associated SNPs to type 2 diabetes mellitus in this study are expression SNPs to the lymphocyte antigen 75 gene, the ubiquitin-specific peptidase 36 gene, and the phosphatidylinositol transfer protein, cytoplasmic 1 gene. | Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus.
Greenawalt DM, Sieberts SK, Cornelis MC, Girman CJ, Zhong H, Yang X, Guinney J, Qi L, Hu FB., Free PMC Article | 11/3/2012 |
| Study identified a deubiquitinating enzyme USP36 that regulates the protein stability of SOD2. | Protein stability of mitochondrial superoxide dismutase SOD2 is regulated by USP36.
Kim MS, Ramakrishna S, Lim KH, Kim JH, Baek KH. | 05/7/2011 |
| Data suggest that nucleophosmin/B23 recruits USP36 to nucleoli, thereby serving as a platform for the regulation of nucleolar protein functions through ubiquitylation/deubiquitylation. | Nucleophosmin/B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36.
Endo A, Kitamura N, Komada M., Free PMC Article | 01/21/2010 |