TWF1 induces autophagy and accelerates malignant phenotype in lung adenocarcinoma via inhibiting the cAMP signaling pathway. | TWF1 induces autophagy and accelerates malignant phenotype in lung adenocarcinoma via inhibiting the cAMP signaling pathway. Wang Y, Zuo R, Huo G, Han Z, He Y, Luo Y, Chen L, Li G, Cui J, Zhu F, Yue P, Yuan D, Sun Y, Li Z, Chen P, Guo H. | 06/29/2023 |
Long non-coding RNA FGD5-AS1 contributes to cisplatin resistance in hepatocellular carcinoma via sponging microRNA-153-3p by upregulating Twinfilin Actin Binding Protein 1 (TWF1). | Long non-coding RNA FGD5-AS1 contributes to cisplatin resistance in hepatocellular carcinoma via sponging microRNA-153-3p by upregulating Twinfilin Actin Binding Protein 1 (TWF1). Yang Y, Shi L, Zhang D, Wu D, An Y, Zhang Y, Chen X., Free PMC Article | 01/22/2022 |
Multifunctional Liposomes Enable Active Targeting and Twinfilin 1 Silencing to Reverse Paclitaxel Resistance in Brain Metastatic Breast Cancer. | Multifunctional Liposomes Enable Active Targeting and Twinfilin 1 Silencing to Reverse Paclitaxel Resistance in Brain Metastatic Breast Cancer. Du J, Shao Y, Hu Y, Chen Y, Cang J, Chen X, Pei W, Miao F, Shen Y, Muddassir M, Zhang Y, Zhang J, Teng G. | 08/28/2021 |
the miR-30c/TWF1 axis may have a role in pancreatic cancer progression | MicroRNA-30c inhibits pancreatic cancer cell proliferation by targeting twinfilin 1 and indicates a poor prognosis. Sun LL, Cheng M, Xu XD., Free PMC Article | 05/16/2020 |
High TWF1 expression is associated with nonsmall-cell lung cancer. | MicroRNA-486-5p improves nonsmall-cell lung cancer chemotherapy sensitivity and inhibits epithelial-mesenchymal transition by targeting twinfilin actin binding protein 1. Jin X, Pang W, Zhang Q, Huang H., Free PMC Article | 03/28/2020 |
Univariate Cox regression analysis showed high expression of TWF1 to be independent prognostic indicator involved in overall survival and recurrence-free survival in lung adenocarcinoma, but not in lung squamous cell carcinoma | Elevated expression of Twinfilin-1 is correlated with inferior prognosis of lung adenocarcinoma. Kaishang Z, Xue P, Shaozhong Z, Yingying F, Yan Z, Chanjun S, Zhenzhen L, Xiangnan L. | 12/22/2018 |
TWF1 and VIM are required for miR-30c to regulate breast cancer cell invasion. | MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. Bockhorn J, Yee K, Chang YF, Prat A, Huo D, Nwachukwu C, Dalton R, Huang S, Swanson KE, Perou CM, Olopade OI, Clarke MF, Greene GL, Liu H., Free PMC Article | 07/27/2013 |
An interleukin-6 family member, interleukin-11 is identified as a secondary target of twinfilin 1 in the microRNA-30c signalling pathway. | MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, Chang YF, Huo D, Wen Y, Swanson KE, Qiu T, Lu J, Park SY, Dolan ME, Perou CM, Olopade OI, Clarke MF, Greene GL, Liu H., Free PMC Article | 06/22/2013 |
protein overexpression promotes cardiomyocyte hypertrophy | Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy. Li Q, Song XW, Zou J, Wang GK, Kremneva E, Li XQ, Zhu N, Sun T, Lappalainen P, Yuan WJ, Qin YW, Jing Q. | 11/27/2010 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Polymorphisms in innate immunity genes and risk of childhood leukemia. Han S, Lan Q, Park AK, Lee KM, Park SK, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Ahn YO, Chanock SJ, Kim H, Rothman N, Kang D., Free PMC Article | 06/30/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesRisk of meningioma and common variation in genes related to innate immunity. Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD. Common variation in genes related to innate immunity and risk of adult glioma. Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ. | 06/30/2010 |
mammals have two twinfilin isoforms, which are differentially expressed and regulated through distinct cellular signaling pathways | Mammals have two twinfilin isoforms whose subcellular localizations and tissue distributions are differentially regulated. Vartiainen MK, Sarkkinen EM, Matilainen T, Salminen M, Lappalainen P. | 01/21/2010 |
These data suggest that the association with an actin monomer induces a first-order conformational change within the twinfilin molecule. | The two ADF-H domains of twinfilin play functionally distinct roles in interactions with actin monomers. Ojala PJ, Paavilainen VO, Vartiainen MK, Tuma R, Weeds AG, Lappalainen P., Free PMC Article | 01/21/2010 |