Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway. | Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway. Wang Z, Zhang Y, Shen Y, Zhou H, Gao Y, Zhu C, Qin X., Free PMC Article | 03/4/2024 |
STAMBPL1 promotes breast cancer cell resistance to cisplatin partially by stabilizing MKP-1 expression. | STAMBPL1 promotes breast cancer cell resistance to cisplatin partially by stabilizing MKP-1 expression. Liu R, Yang G, Bao M, Zhou Z, Mao X, Liu W, Jiang X, Zhu D, Ren X, Huang J, Chen C. | 04/30/2022 |
E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression. | E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression. Wang D, Xu C, Yang W, Chen J, Ou Y, Guan Y, Guan J, Liu Y. | 03/5/2022 |
Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell death. | Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell death. Chaithongyot S, Naumann M., Free PMC Article | 02/5/2022 |
Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1. | Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1. Guo Y, Liu Q, Mallette E, Caba C, Hou F, Fux J, LaPlante G, Dong A, Zhang Q, Zheng H, Tong Y, Zhang W., Free PMC Article | 11/27/2021 |
The Long Non-Coding RNA NEAT1 Promotes Gastric Cancer Cell Proliferation and Invasion by Regulating miR-103a/ STAMBPL1 Axis. | The Long Non-Coding RNA NEAT1 Promotes Gastric Cancer Cell Proliferation and Invasion by Regulating miR-103a/ STAMBPL1 Axis. Yu DJ, Guo CX, Qian J, Li J, Zhu C, Jin X, Wang QK., Free PMC Article | 11/6/2021 |
Systematic analysis reveals a functional role for STAMBPL1 in the epithelial-mesenchymal transition process across multiple carcinomas. | Systematic analysis reveals a functional role for STAMBPL1 in the epithelial-mesenchymal transition process across multiple carcinomas. Ambroise G, Yu TT, Zhang B, Kacal M, Hao Y, Queiroz AL, Ouchida AT, Lindskog C, Norberg E, Vakifahmetoglu-Norberg H., Free PMC Article | 03/27/2021 |
Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation. | Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation. Woo SM, Seo SU, Kubatka P, Min KJ, Kwon TK., Free PMC Article | 09/5/2020 |
STAMBPL1 depletion induces prostate cancer cell apoptosis by promoting XIAP lysosomal degradation. | Targeting the deubiquitinase STAMBPL1 triggers apoptosis in prostate cancer cells by promoting XIAP degradation. Chen X, Shi H, Bi X, Li Y, Huang Z. | 04/18/2020 |
Catalytic Mechanism of Human AMSH-LP Domain Deubiquitinating Enzymes | Quantum Mechanics and Molecular Mechanics Study of the Catalytic Mechanism of Human AMSH-LP Domain Deubiquitinating Enzymes. Zhu W, Liu Y, Ling B. | 11/7/2015 |
Cellular STAMBPL1 is a positive regulator of human T-cell leukemia virus type 1 Tax-mediated NF-kappaB signaling. | An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation. Lavorgna A, Harhaj EW., Free PMC Article | 04/28/2012 |
Observational study of gene-disease association. (HuGE Navigator) | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article | 12/2/2009 |
Data show that associated molecule with the SH3 domain of STAM-like protein (AMSH-LP), unlike AMSH, fails to bind to the SH3 domains of STAM1 (signal transducing adaptor molecule 1) and Grb2. | Identification of AMSH-LP containing a Jab1/MPN domain metalloenzyme motif. Kikuchi K, Ishii N, Asao H, Sugamura K. | 01/21/2010 |
AMSH redirects CaR from slow recycling to down-regulation, reducing CaR expression and decreasing PTHrP secretion. | Calcium-sensing receptor endocytosis links extracellular calcium signaling to parathyroid hormone-related peptide secretion via a Rab11a-dependent and AMSH-sensitive mechanism. Reyes-Ibarra AP, García-Regalado A, Ramírez-Rangel I, Esparza-Silva AL, Valadez-Sánchez M, Vázquez-Prado J, Reyes-Cruz G. | 01/21/2010 |
AMSH and AMSH-LP are anchored on the early endosomal membrane via interaction with the clathrin coat | Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes. Nakamura M, Tanaka N, Kitamura N, Komada M. | 01/21/2010 |