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    STAMBPL1 STAM binding protein like 1 [ Homo sapiens (human) ]

    Gene ID: 57559, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway.

    Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway.
    Wang Z, Zhang Y, Shen Y, Zhou H, Gao Y, Zhu C, Qin X., Free PMC Article

    03/4/2024
    STAMBPL1 promotes breast cancer cell resistance to cisplatin partially by stabilizing MKP-1 expression.

    STAMBPL1 promotes breast cancer cell resistance to cisplatin partially by stabilizing MKP-1 expression.
    Liu R, Yang G, Bao M, Zhou Z, Mao X, Liu W, Jiang X, Zhu D, Ren X, Huang J, Chen C.

    04/30/2022
    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression.

    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression.
    Wang D, Xu C, Yang W, Chen J, Ou Y, Guan Y, Guan J, Liu Y.

    03/5/2022
    Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell death.

    Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell death.
    Chaithongyot S, Naumann M., Free PMC Article

    02/5/2022
    Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1.

    Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1.
    Guo Y, Liu Q, Mallette E, Caba C, Hou F, Fux J, LaPlante G, Dong A, Zhang Q, Zheng H, Tong Y, Zhang W., Free PMC Article

    11/27/2021
    The Long Non-Coding RNA NEAT1 Promotes Gastric Cancer Cell Proliferation and Invasion by Regulating miR-103a/ STAMBPL1 Axis.

    The Long Non-Coding RNA NEAT1 Promotes Gastric Cancer Cell Proliferation and Invasion by Regulating miR-103a/ STAMBPL1 Axis.
    Yu DJ, Guo CX, Qian J, Li J, Zhu C, Jin X, Wang QK., Free PMC Article

    11/6/2021
    Systematic analysis reveals a functional role for STAMBPL1 in the epithelial-mesenchymal transition process across multiple carcinomas.

    Systematic analysis reveals a functional role for STAMBPL1 in the epithelial-mesenchymal transition process across multiple carcinomas.
    Ambroise G, Yu TT, Zhang B, Kacal M, Hao Y, Queiroz AL, Ouchida AT, Lindskog C, Norberg E, Vakifahmetoglu-Norberg H., Free PMC Article

    03/27/2021
    Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation.

    Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation.
    Woo SM, Seo SU, Kubatka P, Min KJ, Kwon TK., Free PMC Article

    09/5/2020
    STAMBPL1 depletion induces prostate cancer cell apoptosis by promoting XIAP lysosomal degradation.

    Targeting the deubiquitinase STAMBPL1 triggers apoptosis in prostate cancer cells by promoting XIAP degradation.
    Chen X, Shi H, Bi X, Li Y, Huang Z.

    04/18/2020
    Catalytic Mechanism of Human AMSH-LP Domain Deubiquitinating Enzymes

    Quantum Mechanics and Molecular Mechanics Study of the Catalytic Mechanism of Human AMSH-LP Domain Deubiquitinating Enzymes.
    Zhu W, Liu Y, Ling B.

    11/7/2015
    Cellular STAMBPL1 is a positive regulator of human T-cell leukemia virus type 1 Tax-mediated NF-kappaB signaling.

    An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation.
    Lavorgna A, Harhaj EW., Free PMC Article

    04/28/2012
    Observational study of gene-disease association. (HuGE Navigator)

    A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
    Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article

    12/2/2009
    Data show that associated molecule with the SH3 domain of STAM-like protein (AMSH-LP), unlike AMSH, fails to bind to the SH3 domains of STAM1 (signal transducing adaptor molecule 1) and Grb2.

    Identification of AMSH-LP containing a Jab1/MPN domain metalloenzyme motif.
    Kikuchi K, Ishii N, Asao H, Sugamura K.

    01/21/2010
    AMSH redirects CaR from slow recycling to down-regulation, reducing CaR expression and decreasing PTHrP secretion.

    Calcium-sensing receptor endocytosis links extracellular calcium signaling to parathyroid hormone-related peptide secretion via a Rab11a-dependent and AMSH-sensitive mechanism.
    Reyes-Ibarra AP, García-Regalado A, Ramírez-Rangel I, Esparza-Silva AL, Valadez-Sánchez M, Vázquez-Prado J, Reyes-Cruz G.

    01/21/2010
    AMSH and AMSH-LP are anchored on the early endosomal membrane via interaction with the clathrin coat

    Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.
    Nakamura M, Tanaka N, Kitamura N, Komada M.

    01/21/2010
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