| Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders. | Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Zhang Z, Hou M, Ou H, Wang D, Li Z, Zhang H, Lu J., Free PMC Article | 03/3/2023 |
| Neuroligin-2 as a central organizer of inhibitory synapses in health and disease. | Neuroligin-2 as a central organizer of inhibitory synapses in health and disease.
Ali H, Marth L, Krueger-Burg D. | 11/13/2021 |
| Neuroligin-2 dependent conformational activation of collybistin reconstituted in supported hybrid membranes. | Neuroligin-2 dependent conformational activation of collybistin reconstituted in supported hybrid membranes.
Schäfer J, Förster L, Mey I, Papadopoulos T, Brose N, Steinem C., Free PMC Article | 03/28/2021 |
| nucleus accumbens neuroligin-2 has a role in depression and stress susceptibility | Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility.
Heshmati M, Aleyasin H, Menard C, Christoffel DJ, Flanigan ME, Pfau ML, Hodes GE, Lepack AE, Bicks LK, Takahashi A, Chandra R, Turecki G, Lobo MK, Maze I, Golden SA, Russo SJ., Free PMC Article | 07/28/2018 |
| e found that NLGN3 function at inhibitory synapses in rat CA1 depends on the presence of NLGN2 and identified a domain in the extracellular region that accounted for this functional difference between NLGN2 and 3 specifically at inhibitory synapses. | Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses.
Nguyen QA, Horn ME, Nicoll RA., Free PMC Article | 11/26/2017 |
| This is the first report of an NLGN2 nonsense variant in humans, adding to the accumulating evidence that links synaptic proteins with a spectrum of neurodevelopmental phenotypes. | Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity.
Parente DJ, Garriga C, Baskin B, Douglas G, Cho MT, Araujo GC, Shinawi M. | 10/21/2017 |
| MDGAs regulate the formation of neuroligin-neurexin trans-synaptic bridges by sterically blocking access of neurexins to neuroligins. | Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges.
Gangwar SP, Zhong X, Seshadrinathan S, Chen H, Machius M, Rudenko G., Free PMC Article | 08/5/2017 |
| Neuroligin-2 was down-regulated in aganglionic colonic segments from Hirschsprung's disease patients. | The down-regulation of neuroligin-2 and the correlative clinical significance of serum GABA over-expression in Hirschsprung's disease.
Yang H, Niu J, Wang J, Zhang F, Zhang Q, Zhang W, Li A. | 10/31/2015 |
| Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic beta cell function | Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic β cell function.
Suckow AT, Zhang C, Egodage S, Comoletti D, Taylor P, Miller MT, Sweet IR, Chessler SD., Free PMC Article | 09/22/2012 |
| Data identified the R215H mutant as a loss-of-function mutant in inducing GABAergic synaptogenesis. Data also suggests that defects in GABAergic synapse formation in the brain may be an important contributing factor for the onset of schizophrenia. | Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia.
Sun C, Cheng MC, Qin R, Liao DL, Chen TT, Koong FJ, Chen G, Chen CH., Free PMC Article | 12/17/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. | 01/11/2009 |