| [Microtubule-associated tumor suppressor 1 inhibits hemin-induced apoptosis of vascular endothelial cells via hemeoxygenase 1]. | [Microtubule-associated tumor suppressor 1 inhibits hemin-induced apoptosis of vascular endothelial cells via hemeoxygenase 1].
Wu SY, Cheng KR, Zhou YY, Wang YF. | 04/26/2024 |
| Long Noncoding RNA MIR600HG Binds to MicroRNA-125a-5p to Prevent Pancreatic Cancer Progression Via Mitochondrial Tumor Suppressor 1-Dependent Suppression of Extracellular Regulated Protein Kinases Signaling Pathway. | Long Noncoding RNA MIR600HG Binds to MicroRNA-125a-5p to Prevent Pancreatic Cancer Progression Via Mitochondrial Tumor Suppressor 1-Dependent Suppression of Extracellular Regulated Protein Kinases Signaling Pathway.
Chen F, Zheng X, Liang W, Jiang C, Su D, Fu B. | 10/28/2023 |
| MTUS1 is a promising diagnostic and prognostic biomarker for colorectal cancer. | MTUS1 is a promising diagnostic and prognostic biomarker for colorectal cancer.
Cheng LY, Huang MS, Zhong HG, Ru HM, Mo SS, Wei CY, Su ZJ, Mo XW, Yan LH, Tang WZ., Free PMC Article | 08/27/2022 |
| In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function. | In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function.
Rozario LT, Sharker T, Nila TA., Free PMC Article | 11/22/2021 |
| Microtubule-Associated Protein ATIP3, an Emerging Target for Personalized Medicine in Breast Cancer. | Microtubule-Associated Protein ATIP3, an Emerging Target for Personalized Medicine in Breast Cancer.
Haykal MM, Rodrigues-Ferreira S, Nahmias C., Free PMC Article | 11/22/2021 |
| RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability. | RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability.
Lv Q, Dong F, Zhou Y, Cai Z, Wang G., Free PMC Article | 04/13/2021 |
| Reduced long non-coding RNA PTENP1 contributed to proliferation and invasion via miR-19b/MTUS1 axis in patients with cervical cancer. | Reduced long non-coding RNA PTENP1 contributed to proliferation and invasion via miR-19b/MTUS1 axis in patients with cervical cancer.
Ou L, Xiang TY, Hao XY, Wang DZ, Zeng Q. | 04/3/2021 |
| Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length. | Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length.
Nehlig A, Seiler C, Steblyanko Y, Dingli F, Arras G, Loew D, Welburn J, Prigent C, Barisic M, Nahmias C. | 03/6/2021 |
| MicroRNA-765 targets MTUS1 to promote the progression of osteosarcoma via mediating ERK/EMT pathway. | MicroRNA-765 targets MTUS1 to promote the progression of osteosarcoma via mediating ERK/EMT pathway.
Lv DB, Zhang JY, Gao K, Yu ZH, Sheng WC, Yang G, Gao YZ. | 09/19/2020 |
| MTUS1 may act as tumor suppressor and might be a potential biomarker for predicting prognosis in GBC. | Loss of MTUS1 Expression Is Associated With Poor Prognosis in Patients With Gallbladder Carcinoma.
Sim J, Kim Y, Kim H, Bang S, Jee S, Park S, Shin SJ, Jang K., Free PMC Article | 06/6/2020 |
| Low expression of MTUS1 correlates to DNA methylation and histone deacetylation in human NSCLC. | DNA methylation regulates Microtubule-associated tumor suppressor 1 in human non-small cell lung carcinoma.
Parbin S, Pradhan N, Das L, Saha P, Deb M, Sengupta D, Patra SK. | 05/16/2020 |
| ATIP3 is an important regulator of mitotic integrity. | Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy.
Rodrigues-Ferreira S, Nehlig A, Moindjie H, Monchecourt C, Seiler C, Marangoni E, Chateau-Joubert S, Dujaric ME, Servant N, Asselain B, de Cremoux P, Lacroix-Triki M, Arnedos M, Pierga JY, André F, Nahmias C., Free PMC Article | 04/25/2020 |
| studies emphasize the importance of studying combinatorial expression of EB1 and ATIP3 genes and proteins rather than each biomarker alone. A population of highly aggressive breast tumors expressing high-EB1/low-ATIP3 may be considered for the development of new molecular therapies. | Combinatorial expression of microtubule-associated EB1 and ATIP3 biomarkers improves breast cancer prognosis.
Rodrigues-Ferreira S, Nehlig A, Monchecourt C, Nasr S, Fuhrmann L, Lacroix-Triki M, Garberis I, Scott V, Delaloge S, Pistilli B, Vielh P, Dubois T, Vincent-Salomon A, André F, Nahmias C. | 06/15/2019 |
| The N-terminal coiled-coil domain of MTUS1 interacted with the mitochondrial membrane proteins. | Microtubule associated tumor suppressor 1 interacts with mitofusins to regulate mitochondrial morphology in endothelial cells.
Wang Y, Huang Y, Liu Y, Li J, Hao Y, Yin P, Liu Z, Chen J, Wang Y, Wang N, Zhang P. | 02/16/2019 |
| MTUS1 is not only involved in the formation and progression of human cancers but also involved in the complex pathological conditions such as cardiac hypertrophy, atherosclerosis, and SLE-like lymphoproliferative diseases. Several molecular mechanisms such as proliferation, differentiation, DNA repair, inflammation, vascular remodeling and senescence appear to be tightly regulated by the MTUS1-encoded proteins. | MTUS1, a gene encoding angiotensin-II type 2 (AT2) receptor-interacting proteins, in health and disease, with special emphasis on its role in carcinogenesis.
Bozgeyik I, Yumrutas O, Bozgeyik E. | 10/20/2017 |
| findings have provided the first clues regarding the roles of miR-19a/b, which appear to function as oncomirs in lung cancer by downregulating MTUS1. | Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer.
Gu Y, Liu S, Zhang X, Chen G, Liang H, Yu M, Liao Z, Zhou Y, Zhang CY, Wang T, Wang C, Zhang J, Chen X., Free PMC Article | 07/15/2017 |
| angiotensin II type 2 receptor-interacting protein 3a presents potential in suppressing the proliferation and aggressiveness of ovarian carcinoma cells through the high mobility group AT-hook 2-mediated extracellular signal-regulated kinase/epithelial-to-mesenchymal transition signal pathway. | Angiotensin II type 2 receptor-interacting protein 3a inhibits ovarian carcinoma metastasis via the extracellular HMGA2-mediated ERK/EMT pathway.
Ping H, Guo L, Xi J, Wang D. | 07/15/2017 |
| Our findings showed that MTUS1 regulates the p38 MAPK-mediated cytokine production in ECs. MTUS1 gene probably plays a protective role against pro-inflammatory response of ECs. | MTUS1 silencing promotes E-selectin production through p38 MAPK-dependent CREB ubiquitination in endothelial cells.
Wang Y, Dai X, Liu Y, Li J, Liu Z, Yin P, Chen J, Wang Y, Wang N, Zhang P. | 06/3/2017 |
| MTUS1 targeting miRNAs may play key roles in the development of CRC by downregulating tumor suppressor MTUS1. | MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations.
Ozcan O, Kara M, Yumrutas O, Bozgeyik E, Bozgeyik I, Celik OI, Ozcan O, Kara M, Yumrutas O, Bozgeyik E, Bozgeyik I, Celik OI. | 02/18/2017 |
| Study reports differential expression of MTUS1 and its regulatory miRNAs in breast cancer and fibroadenoma tissues; among MTUS1 targeting miRNAs, miR-183-5p was overexpressed in breast cancer and down-regulated in fibroadenoma tissues; expression levels of MTUS1 and miR-183-5p correlated with clinical parameters. In particular, MTUS1 was found to be diminished and miR-183-5p was elevated with advancing stage. | MTUS1 tumor suppressor and its miRNA regulators in fibroadenoma and breast cancer.
Kara M, Kaplan M, Bozgeyik I, Ozcan O, Celik OI, Bozgeyik E, Yumrutas O. | 01/14/2017 |
| We propose a novel mechanism by which ATIP3-EB1 interaction indirectly reduces the kinetics of EB1 exchange on its recognition site, thereby accounting for negative regulation of microtubule dynamic instability | Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3.
Velot L, Molina A, Rodrigues-Ferreira S, Nehlig A, Bouchet BP, Morel M, Leconte L, Serre L, Arnal I, Braguer D, Savina A, Honore S, Nahmias C., Free PMC Article | 10/22/2016 |
| Deregulated microRNA (miRNA) expression has been shown to be involved in the pathogenesis of several types of cancers including colorectal cancer (CRC). MTUS1 targeting miRNAs may play key roles in the development of CRC by downregulating tumor suppressor MTUS1. | MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations.
Ozcan O, Kara M, Yumrutas O, Bozgeyik E, Bozgeyik I, Celik OI, Ozcan O, Kara M, Yumrutas O, Bozgeyik E, Bozgeyik I, Celik OI. | 02/11/2016 |
| Our studies confirm that MTUS1 plays an important role in the progression of salivary adenoid cystic carcinoma , and may serve as a biomarker or therapeutic target for patients with salivary adenoid cystic carcinoma | MTUS1/ATIP3a down-regulation is associated with enhanced migration, invasion and poor prognosis in salivary adenoid cystic carcinoma.
Zhao T, Ding X, Chang B, Zhou X, Wang A., Free PMC Article | 02/6/2016 |
| Data identifies MTUS1 as a tumour suppressor gene in cultured bladder cancer cells and in advanced bladder tumours. | Loss of MTUS1/ATIP expression is associated with adverse outcome in advanced bladder carcinomas: data from a retrospective study.
Rogler A, Hoja S, Giedl J, Ekici AB, Wach S, Taubert H, Goebell PJ, Wullich B, Stöckle M, Lehmann J, Petsch S, Hartmann A, Stoehr R., Free PMC Article | 11/8/2014 |
| The present data suggested MTUS1 as a potential tumor suppressor in gastric cancer and might lead to a better understanding of gastric carcinogenesis. | Loss of MTUS1 in gastric cancer promotes tumor growth and metastasis.
Li X, Liu H, Yu T, Dong Z, Tang L, Sun X. | 03/29/2014 |