| Activation-induced cytidine deaminase an antibody diversification enzyme interacts with chromatin modifier UBN1 in B-cells. | Activation-induced cytidine deaminase an antibody diversification enzyme interacts with chromatin modifier UBN1 in B-cells.
Jaiswal A, Roy R, Tamrakar A, Singh AK, Kar P, Kodgire P., Free PMC Article | 11/14/2023 |
| The off-target effects of AID in carcinogenesis. | The off-target effects of AID in carcinogenesis.
Jiao J, Lv Z, Wang Y, Fan L, Yang A., Free PMC Article | 08/22/2023 |
| Activation-induced cytidine deaminase displays an alternative co-factor for modulating PIM1 expression in diffuse large B cell lymphoma cell lines. | Activation-induced cytidine deaminase displays an alternative co-factor for modulating PIM1 expression in diffuse large B cell lymphoma cell lines.
Wang Y, Miao Y, Zhou W, Bi Y, Ji Y, Ma Y. | 06/15/2023 |
| [Activation-induced cytidine deaminase (AID) involved in the regulation of B cell immune senescence]. | [Activation-induced cytidine deaminase (AID) involved in the regulation of B cell immune senescence].
Xiao J, Li J, Yao X. | 06/2/2023 |
| Epstein-Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma. | Epstein-Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma.
Summerauer AM, Jäggi V, Ogwang R, Traxel S, Colombo L, Amundsen E, Eyer T, Subramanian B, Fehr J, Mantel PY, Idro R, Bürgler S., Free PMC Article | 08/13/2022 |
| Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops. | Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops.
Sakhtemani R, Perera MLW, Hübschmann D, Siebert R, Lawrence MS, Bhagwat AS., Free PMC Article | 06/11/2022 |
| AID is a poor prognostic marker of high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements. | AID is a poor prognostic marker of high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements.
Miyaoka M, Kikuti YY, Carreras J, Itou A, Ikoma H, Tomita S, Shiraiwa S, Ando K, Nakamura N. | 05/21/2022 |
| USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID. | USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID.
Luo Y, Zhang X, Chen R, Li R, Liu Y, Zhang J, Liu Q, Si M, Liu J, Wu B, Wang X, Wu S, Zhang Y, Zhang X, Guo D, He X, Pan T, Zhang H., Free PMC Article | 01/15/2022 |
| Optimized high-fidelity 3DPCR to assess potential mitochondrial targeting by activation-induced cytidine deaminase. | Optimized high-fidelity 3DPCR to assess potential mitochondrial targeting by activation-induced cytidine deaminase.
Wu H, Zhang K, Chen Y, Li J, Strout MP, Gu X., Free PMC Article | 11/6/2021 |
| Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis. | Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis.
Traxel S, Lehmann J, Richard S, Sidorov S, Niggli F, Berger C, Nadal D, Bürgler S., Free PMC Article | 07/31/2021 |
| Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction. | Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction.
Català-Moll F, Ferreté-Bonastre AG, Li T, Weichenhan D, Lutsik P, Ciudad L, Álvarez-Prado ÁF, Rodríguez-Ubreva J, Klemann C, Speckmann C, Vilas-Zornoza A, Abolhassani H, Martínez-Gallo M, Dieli-Crimi R, Rivière JG, Martín-Nalda A, Colobran R, Soler-Palacín P, Kracker S, Hammarström L, Prosper F, Durandy A, Grimbacher B, Plass C, Ballestar E., Free PMC Article | 07/10/2021 |
| Structural plasticity of substrate selection by activation-induced cytidine deaminase as a regulator of its genome-wide mutagenic activity. | Structural plasticity of substrate selection by activation-induced cytidine deaminase as a regulator of its genome-wide mutagenic activity.
King JJ, Larijani M. | 07/10/2021 |
| Clinical implications of experimental analyses of AID function on predictive computational tools: Challenge of missense variants. | Clinical implications of experimental analyses of AID function on predictive computational tools: Challenge of missense variants.
Abolhassani H, Marcotte H, Fang M, Hammarström L. | 06/5/2021 |
| Upregulated Expression of Activation-Induced Cytidine Deaminase in Ocular Adnexal Marginal Zone Lymphoma with IgG4-Positive Cells. | Upregulated Expression of Activation-Induced Cytidine Deaminase in Ocular Adnexal Marginal Zone Lymphoma with IgG4-Positive Cells.
Nishikori A, Nishimura Y, Shibata R, Ohshima KI, Gion Y, Ikeda T, Nishimura MF, Yoshino T, Sato Y., Free PMC Article | 05/15/2021 |
| AID Overlapping and Poleta Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes. | AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes.
Tang C, Bagnara D, Chiorazzi N, Scharff MD, MacCarthy T., Free PMC Article | 03/27/2021 |
| Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV. | Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV.
Shponka V, Reveles CY, Alam S, Jaramillo M, Maguire A, Rimsza LM, Kendrick S., Free PMC Article | 03/13/2021 |
| Activation-induced cytidine deaminase overexpression in double-hit lymphoma: potential target for novel anticancer therapy. | Activation-induced cytidine deaminase overexpression in double-hit lymphoma: potential target for novel anticancer therapy.
Zhang J, Shi Y, Zhao M, Hu H, Huang H., Free PMC Article | 01/9/2021 |
| Role of AID in the temporal pattern of acquisition of driver mutations in multiple myeloma. | Role of AID in the temporal pattern of acquisition of driver mutations in multiple myeloma.
Maura F, Rustad EH, Yellapantula V, Łuksza M, Hoyos D, Maclachlan KH, Diamond BT, Greenbaum BD, Morgan G, Lesokhin A, Papaemmanuil E, Landgren O. | 10/3/2020 |
| RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase. | RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase.
Yin Z, Kobayashi M, Hu W, Higashi K, Begum NA, Kurokawa K, Honjo T., Free PMC Article | 08/22/2020 |
| This report suggests that mmunoglobulin (Ig) G4-related disease (IgG4-RD) has several specific causes of Activation-induced cytidine deaminase (AID) up-regulation in addition to inflammation. Furthermore, chronic inflammation-associated AID-mediated oncogenesis is possible in IgG4-RD. | Up-regulation of activation-induced cytidine deaminase and its strong expression in extra-germinal centres in IgG4-related disease.
Gion Y, Takeuchi M, Shibata R, Takata K, Miyata-Takata T, Orita Y, Tachibana T, Yoshino T, Sato Y., Free PMC Article | 07/25/2020 |
| AID is an oncogene that might induce tumorigenesis through DNA demethylation | Activation-Induced Cytidine Deaminase Expression Facilitates the Malignant Phenotype and Epithelial-to-Mesenchymal Transition in Clear Cell Renal Cell Carcinoma.
Che Z, Fan J, Zhou Z, Li Q, Ma Z, Hu Z, Wu Y, Jin Y, Su Y, Liang P, Li H. | 07/25/2020 |
| AID is an oncogene that mediates tumourigenesis in bladder urothelial cell carcinoma via DNA demethylation | AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma.
Li H, Li Q, Ma Z, Zhou Z, Fan J, Jin Y, Wu Y, Cheng F, Liang P., Free PMC Article | 05/16/2020 |
| AID-catalyzed deamination during Pol II transcription elongation in conjunction with DSIF transcription factor, is reported. | AID-RNA polymerase II transcription-dependent deamination of IgV DNA.
Pham P, Malik S, Mak C, Calabrese PC, Roeder RG, Goodman MF., Free PMC Article | 05/16/2020 |
| APE1 is not necessary for somatic hypermutation (SHM) in the V and S regions; however, it is required for DNA repair following DNA breakage in class switch recombination (CSR) | Apurinic/apyrimidinic endonuclease 1 (APE1) is dispensable for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation in the immunoglobulin gene.
Islam H, Kobayashi M, Honjo T. | 04/11/2020 |
| Data suggest poly(ADP-ribose) polymerase-1 (PARP-1) as a critical local feedback regulator of both activation-induced deaminase (AID) activity and DNA repair during Ig gene diversification. | Restriction of AID activity and somatic hypermutation by PARP-1.
Tepper S, Mortusewicz O, Członka E, Bello A, Schmidt A, Jeschke J, Fischbach A, Pfeil I, Petersen-Mahrt SK, Mangerich A, Helleday T, Leonhardt H, Jungnickel B., Free PMC Article | 12/14/2019 |