| PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling. | PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling.
Su Y, Meng L, Ge C, Liu Y, Zhang C, Yang Y, Tian W, Tian H., Free PMC Article | 07/29/2024 |
| Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma. | Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.
Li Y, Liu X, Zhao F, Zhao Z, Li X, Wang J, Huang B, Chen A., Free PMC Article | 03/4/2024 |
| The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis. | The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis.
Christie J, Anthony CM, Harish M, Mudartha D, Ud Din Farooqee SB, Venkatraman P. | 12/20/2023 |
| PSMD9 is linked to T2D age of onset, years of isolated and combined insulin therapy, irregular menses, and hot flashes. | PSMD9 is linked to T2D age of onset, years of isolated and combined insulin therapy, irregular menses, and hot flashes.
Del Bosque-Plata L, Amin M, Gragnoli C. | 12/31/2022 |
| KIF14 affects cell cycle arrest and cell viability in cervical cancer by regulating the p27(Kip1) pathway. | KIF14 affects cell cycle arrest and cell viability in cervical cancer by regulating the p27(Kip1) pathway.
Zhang J, Buranjiang G, Mutalifu Z, Jin H, Yao L., Free PMC Article | 04/30/2022 |
| UBE2S interacting with TRIM28 in the nucleus accelerates cell cycle by ubiquitination of p27 to promote hepatocellular carcinoma development. | UBE2S interacting with TRIM28 in the nucleus accelerates cell cycle by ubiquitination of p27 to promote hepatocellular carcinoma development.
Zhang RY, Liu ZK, Wei D, Yong YL, Lin P, Li H, Liu M, Zheng NS, Liu K, Hu CX, Yang XZ, Chen ZN, Bian H., Free PMC Article | 03/5/2022 |
| PSMD9 ribosomal protein network maintains nucleolar architecture and WT p53 levels. | PSMD9 ribosomal protein network maintains nucleolar architecture and WT p53 levels.
Ud Din Farooqee SB, Christie J, Venkatraman P. | 11/13/2021 |
| Proteasome modulator 9 (PSMD9) gene rs14259 polymorphism in Alzheimer's disease. | Proteasome modulator 9 (PSMD9) gene rs14259 polymorphism in Alzheimer's disease.
Ozer Y, Ozen F, Diler Y, Yalcin AD, Atasever-Arslan B. | 09/19/2020 |
| Novel Determinant of PSMD9 PDZ Binding | A Novel Determinant of PSMD9 PDZ Binding Guides the Evolution of the First Generation of Super Binding Peptides.
Harish M, Kannan S, Puttagunta S, Pradhan MR, Verma CS, Venkatraman P. | 06/6/2020 |
| Molecular experiments showed that miR2213p was able to bind with the 3'untranslated region (UTR) of p27 and decreased the expression of p27 in nonsmall cell lung cancer cells. | miR‑221‑3p promotes the cell growth of non‑small cell lung cancer by targeting p27.
Yin G, Zhang B, Li J., Free PMC Article | 12/21/2019 |
| Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. | Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer.
Chen J, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML., Free PMC Article | 04/22/2019 |
| These data suggest that Schistosoma japonicum Sjp40 might inhibit hepatic stellate cell activation by promoting cellular senescence via SKP2/P27 signaling pathway. | Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells via SKP2/P27 signaling pathway.
Xu T, Chen J, Zhu D, Chen L, Wang J, Sun X, Hu B, Duan Y., Free PMC Article | 09/1/2018 |
| human epidermal growth factor receptor 2 (HER-2) levels, were correlated well with TSP50/p-Samd2/3 and TSP50/p27 expression status. Thus, our studies revealed a novel regulatory mechanism underlying TSP50-induced cell proliferation and provided a new favorable intervention target for the treatment of breast cancer | Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.
Song ZB, Wu P, Ni JS, Liu T, Fan C, Bao YL, Wu Y, Sun LG, Yu CL, Huang YX, Li YX. | 11/4/2017 |
| Furthermore, inhibition of COPS5 resulted in an elevation of Akt expression and sensitized SOC cells to Akt inhibitor MK2206. Suppression of COPS5 and Akt offers a potential strategy for the treatment of SOC. | COPS5 inhibition arrests the proliferation and growth of serous ovarian cancer cells via the elevation of p27 level.
Zhang H, Zhong A, Sun J, Chen M, Xie S, Zheng H, Wang Y, Yu Y, Guo L, Lu R. | 10/28/2017 |
| Loss of p27 associated with risk for endometrial carcinoma arising in the setting of obesity. | Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity.
McCampbell AS, Mittelstadt ML, Dere R, Kim S, Zhou L, Djordjevic B, Soliman PT, Zhang Q, Wei C, Hursting SD, Lu KH, Broaddus RR, Walker CL., Free PMC Article | 12/17/2016 |
| p53 immunopositivity was more frequent in SCC (65%) than in VC (23%) (P</=0.001). VC had lower p53 as compared with well-differentiated SCC and SCC without lymph node metastasis. No significant difference was seen in pRb, p16, and p27 expression | Expression of Cell Cycle-associated Proteins p53, pRb, p16, p27, and Correlation With Survival: A Comparative Study on Oral Squamous Cell Carcinoma and Verrucous Carcinoma.
Vallonthaiel AG, Singh MK, Dinda AK, Kakkar A, Thakar A, Das SN. | 12/17/2016 |
| The PSMD9 intronic SNPs rs74421874 (IVS3+nt460 G>A) and rs3825172 (IVS3+nt437 C>T) remain significantly associated with insomnia only when taking into account anxiety -and not depression- as covariate. | T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia.
Hao H, Haas MJ, Wu R, Gragnoli C., Free PMC Article | 08/6/2016 |
| Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit 9 (PSMD9), proteasome alpha type 7 subunit (PSMA7) and PSMD13 genes. | Proteasome system dysregulation and treatment resistance mechanisms in major depressive disorder.
Minelli A, Magri C, Barbon A, Bonvicini C, Segala M, Congiu C, Bignotti S, Milanesi E, Trabucchi L, Cattane N, Bortolomasi M, Gennarelli M., Free PMC Article | 07/30/2016 |
| recurrence rate of p27 and/or PTEN-negative patients was higher than that of the positive ones,that should be followed up closely after treatment | Expression of p27 and PTEN and clinical characteristics in early laryngeal squamous cell carcinoma and their correlation with recurrence.
Yang JQ, Liang Z, Wu M, Sun YM, Liu HX., Free PMC Article | 04/23/2016 |
| The present study provided the first evidences that miR-1470 mediated lapatinib induced p27 upregulation by targeting c-jun. | miR-1470 mediates lapatinib induced p27 upregulation by targeting c-jun.
Nie W, Song W, Zhang W, Wang Y, Zhu A, Shao J, Guan X. | 06/6/2015 |
| Staining intensities of cell cycle inhibitors p27 and p57 significantly increased in all parts of preeclamptic placentas compared to control | The expression of cell cycle related proteins PCNA, Ki67, p27 and p57 in normal and preeclamptic human placentas.
Unek G, Ozmen A, Mendilcioglu I, Simsek M, Korgun ET. | 02/28/2015 |
| PSMD9 expression predicts radiotherapy response in breast cancer. | PSMD9 expression predicts radiotherapy response in breast cancer.
Langlands FE, Dodwell D, Hanby AM, Horgan K, Millican-Slater RA, Speirs V, Verghese ET, Smith L, Hughes TA., Free PMC Article | 01/17/2015 |
| Expression of Hath1, Muc2, cyclin D1 and p27 in the xenograft tumors was also detected. | Hath1 inhibits proliferation of colon cancer cells probably through up-regulating expression of Muc2 and p27 and down-regulating expression of cyclin D1.
Zhu DH, Niu BL, Du HM, Ren K, Sun JM, Gong JP. | 10/11/2014 |
| Describe PSMD9 gene SNPs in linkage to generalized anxiety disorder in type 2 diabetic families. | Proteasome modulator 9 gene SNPs, responsible for anti-depressant response, are in linkage with generalized anxiety disorder.
Gragnoli C. | 07/26/2014 |
| The PSMD9 single nucleotide polymorphism(SNP)s IVS3+nt460, IVS3+nt437, and 197G are in linkage with overweight condition and waist circumference in Italians. | Overweight condition and waist circumference and a candidate gene within the 12q24 locus.
Gragnoli C., Free PMC Article | 10/19/2013 |