| Deletion of murine Rhoh leads to de-repression of Bcl-6 via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma. | Deletion of murine Rhoh leads to de-repression of Bcl-6 via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma.
Horiguchi H, Xu H, Duvert B, Ciuculescu F, Yao Q, Sinha A, McGuinness M, Harris C, Brendel C, Troeger A, Chiarle R, Williams DA., Free PMC Article | 02/19/2022 |
| [Zbtb33 Gene Knockout Changes Transcription of the Fgf9, Fgfr3, small es, Cyrillic-capital EM, Cyrillicsmall u, Cyrillicsmall es, Cyrillic and FoxG1 Genes in the Developing Mouse Brain]. | [Zbtb33 Gene Knockout Changes Transcription of the Fgf9, Fgfr3, с-Мус and FoxG1 Genes in the Developing Mouse Brain].
Illarionova NB, Borisova MA, Bazhenova EY, Zabelina DS, Fursenko DV, Kulikov AV. | 06/12/2021 |
| Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells. | Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells.
Hiramatsu S, Watanabe KS, Zeggar S, Asano Y, Miyawaki Y, Yamamura Y, Katsuyama E, Katsuyama T, Watanabe H, Takano-Narazaki M, Matsumoto Y, Kawabata T, Sada KE, Wada J., Free PMC Article | 09/26/2020 |
| Authors used Kaiso-deficient mice to conditionally delete Apc within the intestinal epithelia and demonstrated upregulation of the spindle polarity genes Dlg1 and Dlgap1. | Epigenetic Regulation of Dlg1, via Kaiso, Alters Mitotic Spindle Polarity and Promotes Intestinal Tumorigenesis.
Young MA, May S, Damo A, Yoon YS, Hur MW, Swat W, Parry L. | 01/25/2020 |
| The proposed mechanisms for the increase in the efficiency of somatic reprogramming associated with the Kaiso gene knockout is a decrease in the methylation level of the Oct4 promoter region in mouse embryonic fibroblasts before reprogramming. | Kaiso Gene Knockout Promotes Somatic Cell Reprogramming.
Kaplun DS, Fok RE, Korostina VS, Prokhortchouk EB, Zhenilo SV. | 07/27/2019 |
| We also demonstrate that Kaiso inhibits Znf131 expression, raising the possibility that Kaiso and Znf131 act to fine-tune target gene expression. Together, our findings implicate Znf131 as a co-regulator of Kaiso-mediated biological processes. | The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.
Robinson SC, Donaldson-Kabwe NS, Dvorkin-Gheva A, Longo J, He L, Daniel JM. | 10/28/2017 |
| Kaiso and Sox10 sequentially interact with Tcf7l2 to coordinate the maturation of oligodendrocyte. | Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation.
Zhao C, Deng Y, Liu L, Yu K, Zhang L, Wang H, He X, Wang J, Lu C, Wu LN, Weng Q, Mao M, Li J, van Es JH, Xin M, Parry L, Goldman SA, Clevers H, Lu QR., Free PMC Article | 09/24/2016 |
| Study revealed the involvement of the Zbtb33 gene and, probably, the Kaiso protein in the regulation of locomotion and brain morphology in mice | Knockout Zbtb33 gene results in an increased locomotion, exploration and pre-pulse inhibition in mice.
Kulikov AV, Korostina VS, Kulikova EA, Fursenko DV, Akulov AE, Moshkin MP, Prokhortchouk EB. | 09/17/2016 |
| a mechanistic link between E-cadherin loss and subsequent control of Rho-driven anoikis resistance through p120- and Kaiso-dependent expression of Wnt11, is reported. | Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression.
van de Ven RA, Tenhagen M, Meuleman W, van Riel JJ, Schackmann RC, Derksen PW., Free PMC Article | 02/27/2016 |
| S100A3 is a new target gene of Kaiso in mouse skin | [S100A3 is a new target gene of Kaiso in mouse skin].
Zhigalova NA, Sokolov AS, Prokhortchouk EB, Zhenilo SV. | 07/25/2015 |
| ZBTB33 expression may elicit intestinal inflammation by antagonizing p120ctn function. | The POZ-ZF transcription factor Kaiso (ZBTB33) induces inflammation and progenitor cell differentiation in the murine intestine.
Chaudhary R, Pierre CC, Nanan K, Wojtal D, Morone S, Pinelli C, Wood GA, Robine S, Daniel JM., Free PMC Article | 06/7/2014 |
| derepressed Bcl6 expression may be responsible for increases in germinal centers cell proliferation and splenomegaly of Kaiso knockout mice. | Kaiso is a key regulator of spleen germinal center formation by repressing Bcl6 expression in splenocytes.
Koh DI, Yoon JH, Kim MK, An H, Kim MY, Hur MW. | 05/3/2014 |
| KAISO, similar to SMRT, accelerates the cell cycle and increases fat accumulation upon knockdown, identifying KAISO as an adipogenic repressor that likely modulates the mitotic clonal expansion phase of this process. | Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.
Raghav SK, Waszak SM, Krier I, Gubelmann C, Isakova A, Mikkelsen TS, Deplancke B. | 07/28/2012 |
| Znf131 is a transcriptional activator, a less common function of POZ-ZF proteins, that is negatively regulated by its heterodimerization partner Kaiso. | Kaiso regulates Znf131-mediated transcriptional activation.
Donaldson NS, Nordgaard CL, Pierre CC, Kelly KF, Robinson SC, Swystun L, Henriquez R, Graham M, Daniel JM. | 06/28/2010 |
| The function of Mecps in mouse development and in neural stem cell derivation, maintenance, and differentiation, was investigated. | The methyl-CpG binding proteins Mecp2, Mbd2 and Kaiso are dispensable for mouse embryogenesis, but play a redundant function in neural differentiation.
Martín Caballero I, Hansen J, Leaford D, Pollard S, Hendrich BD., Free PMC Article | 01/21/2010 |
| Human zinc finger protein Kaiso could bind with methylated CpG specifically, only in the assistance of the neighboring flank sequence of the zinc finger domain | [Methylation specific binding activity of zinc finger protein Kaiso].
Zhang BZ, Gu LK, Deng DJ. | 01/21/2010 |
| Our study suggests that this gene is not implicated in the RTT molecular pathogenesis | The X-linked methyl binding protein gene Kaiso is highly expressed in brain but is not mutated in Rett syndrome patients.
Della Ragione F, Tiunova A, Vacca M, Strazzullo M, González E, Armstrong J, Valero R, Campanile C, Pineda M, Hulten M, Monros E, D'Esposito M, Prokhortchouk E. | 01/21/2010 |
| Kaiso translocates to the nucleus to regulate transcription of genes with diverse roles in cell growth and development | Nuclear import of the BTB/POZ transcriptional regulator Kaiso.
Kelly KF, Otchere AA, Graham M, Daniel JM. | 01/21/2010 |
| p120-catenin and Kaiso are essential components of a new developmental gene regulatory pathway that controls vertebrate morphogenesis. | Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin.
Kim SW, Park JI, Spring CM, Sater AK, Ji H, Otchere AA, Daniel JM, McCrea PD. | 01/21/2010 |
| Kaiso-null mice showed a delayed onset of intestinal tumorigenesis. | Kaiso-deficient mice show resistance to intestinal cancer.
Prokhortchouk A, Sansom O, Selfridge J, Caballero IM, Salozhin S, Aithozhina D, Cerchietti L, Meng FG, Augenlicht LH, Mariadason JM, Hendrich B, Melnick A, Prokhortchouk E, Clarke A, Bird A., Free PMC Article | 01/21/2010 |
| These results provide the first experimental evidence that rapsyn is a direct sequence-specific target of Kaiso and delta-catenin. | Regulation of the rapsyn promoter by kaiso and delta-catenin.
Rodova M, Kelly KF, VanSaun M, Daniel JM, Werle MJ., Free PMC Article | 01/21/2010 |