| MMP26 is overexpressed in prostatic neoplasms patients, and can serve as a serum disease biomarker. | MMP26: A potential biomarker for prostate cancer.
Cheng T, Li F, Wei R, Lv MQ, Zhou Y, Dai Y, Yuan Y, Jiang GY, Ma D, Gao QL. | 07/28/2018 |
| The luciferase report assay demonstrated that MMP26 is a target gene of miR-125b. And the expression profile of MMP26 showed an inverse relationship with miR-125b in vivo and in vitro. | MiR-125b regulates endometrial receptivity by targeting MMP26 in women undergoing IVF-ET with elevated progesterone on HCG priming day.
Chen C, Zhao Y, Yu Y, Li R, Qiao J., Free PMC Article | 01/27/2018 |
| MMP26+CXCR4+ cells may be circulating tumor cells in hepatocellular carcinoma. | Circulating Hepatocellular Carcinoma Cells are Characterized by CXCR4 and MMP26.
Yu C, Wang Z, Xu X, Xiang W, Huang X. | 05/28/2016 |
| We found that only inhibition of JNK significantly decreased the activation of MMP26 in response to FGF1 stimulation, suggesting that activation of FGFR1 signaling may activate JNK to activate MMP26 in non-small-cell lung cancer | Activation of FGF receptor signaling promotes invasion of non-small-cell lung cancer.
Zhao D, Lu Y, Yang C, Zhou X, Xu Z. | 08/8/2015 |
| Overexpression of MMP26 in SW1353 cells increased cell invasiveness, while inhibition of MMP26 decreased cell invasiveness. | Regulation of chondrosarcoma invasion by MMP26.
Xu X, Ma J, Li C, Zhao W, Xu Y. | 05/16/2015 |
| The binding of MMP-26 to GDF15 was responsible for the processing and maturation of pro-GDF15, and the process was dependent on enzymatic activity of MMP-26. In human placental trophoblast cells, MMP-26 could facilitate the pro-apoptotic effect of GDF15. | Maturation of growth differentiation factor 15 in human placental trophoblast cells depends on the interaction with Matrix Metalloproteinase-26.
Li S, Wang Y, Cao B, Wu Y, Ji L, Li YX, Liu M, Zhao Y, Qiao J, Wang H, Wang H, Han C, Wang YL. | 01/17/2015 |
| matrilysin-2 was an independent prognostic marker for patients with colorectal cancer | Matrilysin-2 expression in colorectal cancer is associated with overall survival of patients.
Hu Q, Yan C, Xu C, Yan H, Qing L, Pu Y, He Z, Li X. | 06/14/2014 |
| These results demonstrate that the HOXA10-mediated expression of MMP-26 promotes embryo adhesion during the process of embryonic implantation. | Activation of matrix metalloproteinase-26 by HOXA10 promotes embryo adhesion in vitro.
Jiang Y, Yan G, Zhang H, Shan H, Kong C, Yan Q, Xue B, Diao Z, Hu Y, Sun H. | 05/10/2014 |
| The MMP-26 promoter region contains a putative ER response element. | Estrogen and estrogen receptor induce matrix metalloproteinase-26 expression in endometrial carcinoma cells.
Nishi H, Kuroda M, Isaka K. | 03/1/2014 |
| expression of MMP-26 protein was predominantly located in pre- and early-invasive areas suggesting MMP-26 expression as an early event in promoting GM-CSF dependent tumor invasion. | GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expression.
Gutschalk CM, Yanamandra AK, Linde N, Meides A, Depner S, Mueller MM., Free PMC Article | 02/8/2014 |
| Molecular analyses showed significant downregulation of expression of MMP-26 (p=0.03), and significant 9.8-fold upregulation of TGF-beta (p=0.01) in more degenerated discs vs. healthier discs. | Matrix metalloproteinase-26, a novel MMP, is constitutively expressed in the human intervertebral disc in vivo and in vitro.
Gruber HE, Hoelscher GL, Ingram JA, Hanley EN Jr. | 05/5/2012 |
| MMP-26 plays an important role in local invasion at least in part through coordination with MMP-9. | Non-small cell lung cancer invasion and metastasis promoted by MMP-26.
Zhang Y, Zhao H, Wang Y, Lin Y, Tan Y, Fang X, Zheng L. | 01/14/2012 |
| direct association observed between morphological scores of malignancy and MMP immunoreactivity, with the association being significant for MMP-26. present results demonstrate important role of MMPs in development of SCCs of lower lip and tongue. | Immunohistochemical expression of matrix metalloproteinases in squamous cell carcinoma of the tongue and lower lip.
Barros SS, Henriques ÁC, Pereira KM, de Medeiros AM, Galvão HC, Freitas Rde A. | 12/10/2011 |
| MMP-26 expression may be associated with multiple human carcinomas. MMP-26 may also contribute to smooth muscle function in the human prostate and cardiovascular system. | Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells.
Zhao YG, Xiao AZ, Ni J, Man YG, Sang QX. | 08/20/2011 |
| role of these proteins in the process of invasion and metastasis cannot be ruled out since their presence is more marked along the tumor invasion front compared to more central areas of squamous cell carcinoma of the tongue | Matrilysins may not predict the metastatic potential in squamous cell carcinoma of the tongue.
de Amorim RF, da Silveira EJ, Queiroz LM, Galvão HC, de Souza LB, de Almeida Freitas R. | 10/23/2010 |
| Meta-analysis of gene-disease association. (HuGE Navigator) | Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G, Ovarian Cancer Association Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer)., Free PMC Article | 09/15/2010 |
| GnRH I and II could up-regulate MMP-26 expression through the JNK signaling pathway in human trophoblast-like/trophoblast cells. | GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts.
Liu J, Cao B, Li YX, Wu XQ, Wang YL., Free PMC Article | 05/10/2010 |
| MMP-26 contributes to tumor cell invasion, migration and angiogenesis | Expression of Matrix Metalloproteinase-26 promotes human glioma U251 cell invasion in vitro and in vivo.
Deng Y, Li W, Li Y, Yang H, Xu H, Liang S, Zhang L, Li Y. | 03/22/2010 |
| MMP-26 expression in stroma is associated with larger Merkel cell carcinoma with poor prognosis. | Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma.
Suomela S, Koljonen V, Skoog T, Kukko H, Böhling T, Saarialho-Kere U. | 02/8/2010 |
| MMP-26 and MMP-9 may contribute to the more aggressive behavior of squamous cell carcinomas in organ transplant recipients | Matrix metalloproteinase-26 is present more frequently in squamous cell carcinomas of immunosuppressed compared with immunocompetent patients.
Kuivanen T, Jeskanen L, Kyllönen L, Isaka K, Saarialho-Kere U. | 01/21/2010 |
| MMP-26 may be served as a tumor marker in monitoring progression and predicting prognosis of non-small cell lung cancer. | Expression and clinical significance of matrix metalloproteinase (MMP)-26 protein in non-small cell lung cancer.
Li L, Mei TH, Zhou XD, Zhang XG. | 01/21/2010 |
| expression of transmembrane 4 superfamily member 4 (TM4SF4) and matrix metalloproteinase 26 (MMP26) was found to be significantly decreased during the implantation window in patients with polycystic ovary syndrome. | Microarray evaluation of endometrial receptivity in Chinese women with polycystic ovary syndrome.
Qiao J, Wang L, Li R, Zhang X. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAssociation between polymorphisms of matrix metalloproteinase 11 (MMP-11) and Kawasaki disease in the Korean population.
Ban JY, Kim SK, Kang SW, Yoon KL, Chung JH. Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.
Drenos F, Talmud PJ, Casas JP, Smeeth L, Palmen J, Humphries SE, Hingorani AD. Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study.
Cauchi S, Proença C, Choquet H, Gaget S, De Graeve F, Marre M, Balkau B, Tichet J, Meyre D, Vaxillaire M, Froguel P, D.E.S.I.R. Study Group. | 04/3/2008 |
| The putative role of MMP-26 as a marker of metastasesin pancreatic cancer warrants further studies | Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma.
Bister V, Skoog T, Virolainen S, Kiviluoto T, Puolakkainen P, Saarialho-Kere U. | 01/21/2010 |
| Results indicate that MMP-26 and TIMP-4 may play an integral role during the conversion of high-grade prostatic intraepithelial neoplasia to invasive cancer and may also serve as markers for early prostate cancer diagnosis. | Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor.
Lee S, Desai KK, Iczkowski KA, Newcomer RG, Wu KJ, Zhao YG, Tan WW, Roycik MD, Sang QX. | 01/21/2010 |