FoxO3 transcription factor promotes autophagy after oxidative stress injury in HT22 cells. | FoxO3 transcription factor promotes autophagy after oxidative stress injury in HT22 cells. Deng A, Ma L, Zhou X, Wang X, Wang S, Chen X. | 07/25/2024 |
Expression of FoxO3a in sepsis mice and its association with lymphocyte apoptosis. | Expression of FoxO3a in sepsis mice and its association with lymphocyte apoptosis. Wen Y, Li Y, Guo J, Shang K. | 06/6/2024 |
Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation. | Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation. Pierzynowska K, Podlacha M, Gaffke L, Rintz E, Wiśniewska K, Cyske Z, Węgrzyn G., Free PMC Article | 06/5/2024 |
Foxo3 regulates cortical and medullary thymic epithelial cell homeostasis with implications in T cell development. | Foxo3 regulates cortical and medullary thymic epithelial cell homeostasis with implications in T cell development. Ribeiro C, Ferreirinha P, Landry JJM, Macedo F, Sousa LG, Pinto R, Benes V, Alves NL., Free PMC Article | 05/29/2024 |
PRMT6-FOXO3A ATTENUATES APOPTOSIS BY UPREGULATING PARKIN EXPRESSION IN INTESTINAL ISCHEMIA-REPERFUSION INJURY. | PRMT6-FOXO3A ATTENUATES APOPTOSIS BY UPREGULATING PARKIN EXPRESSION IN INTESTINAL ISCHEMIA-REPERFUSION INJURY. Wu X, Zhou Y, Xu H, Zhang X, Yao L, Li J, Li X. | 05/10/2024 |
Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a. | Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a. Yang C, Kang F, Huang X, Wu W, Hou G, Zheng K, Han M, Kan B, Zhang Z, Li J. | 04/16/2024 |
p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6. | p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6. Cheng Y, Zhang M, Xu R, Fu L, Xue M, Xu C, Tang C, Fang T, Liu X, Sun B, Chen L. | 03/27/2024 |
GDF11 mitigates high glucose-induced cardiomyocytes apoptosis by inhibiting the ALKBH5-FOXO3-CDR1as/Hippo signaling pathway. | GDF11 mitigates high glucose-induced cardiomyocytes apoptosis by inhibiting the ALKBH5-FOXO3-CDR1as/Hippo signaling pathway. Shao Y, Li M, Wang Y, Qu Y, Gong M, Yu Q, Yang X, Liu D, Li H, Wang Y, Sun H, Zhang Y, Zhang X, Liu T, Liu J, Gong T, Sun Y, Du Z, Jiao L, Zhang Y. | 03/5/2024 |
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1. | Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1. Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B., Free PMC Article | 01/30/2024 |
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma. | The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma. Niu J, Yan T, Guo W, Wang W, Ren T, Huang Y, Zhao Z, Yu Y, Chen C, Huang Q, Lou J, Guo L., Free PMC Article | 10/20/2023 |
PFKFB3-driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered FoxO3 and lactate production. | PFKFB3-driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered FoxO3 and lactate production. Chen J, Yu H, Tan X, Mok SWF, Xie Y, Wang Y, Jiang X, Macrae VE, Lan L, Fu X, Zhu D. | 09/22/2023 |
Foxo3 Knockdown Mediates Decline of Myod1 and Myog Reducing Myoblast Conversion to Myotubes. | Foxo3 Knockdown Mediates Decline of Myod1 and Myog Reducing Myoblast Conversion to Myotubes. Gellhaus B, Böker KO, Gsaenger M, Rodenwaldt E, Hüser MA, Schilling AF, Saul D., Free PMC Article | 09/22/2023 |
SIRT3 alleviates sepsis-induced acute lung injury by inhibiting pyroptosis via regulating the deacetylation of FoxO3a. | SIRT3 alleviates sepsis-induced acute lung injury by inhibiting pyroptosis via regulating the deacetylation of FoxO3a. Wu Z, Wang Y, Lu S, Yin L, Dai L. | 09/18/2023 |
FoxO3 Modulates Circadian Rhythms in Neural Stem Cells. | FoxO3 Modulates Circadian Rhythms in Neural Stem Cells. Draijer S, Timmerman R, Pannekeet J, van Harten A, Farshadi EA, Kemmer J, van Gilst D, Chaves I, Hoekman MFM., Free PMC Article | 09/12/2023 |
Pregnancy-induced physiological hypertrophic preconditioning attenuates pathological myocardial hypertrophy by activation of FoxO3a. | Pregnancy-induced physiological hypertrophic preconditioning attenuates pathological myocardial hypertrophy by activation of FoxO3a. Xie J, Zheng C, Shen M, Lu W, Li M, He M, Chen L, Ma S, Zhu Y, Lin H, Xiu J, Liao W, Bin J, Liao Y., Free PMC Article | 08/30/2023 |
Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1. | Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1. Li S, Xiao H, Sun X, Chen Z, Lin Z, Li C, Zeng J, Xu Z, Cheng Y, Huang H. | 08/17/2023 |
Downregulation of circ-Foxo3 in breast cancer stem-like cells. | Downregulation of circ-Foxo3 in breast cancer stem-like cells. Kamalabadi-Farahani M, Atashi A, Eslami MM., Free PMC Article | 07/13/2023 |
FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis. | FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis. Ghimire J, Iftikhar R, Penrose HM, Snarski P, Ruiz E, Savkovic SD., Free PMC Article | 06/15/2023 |
Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. | Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Acharya BR, Fang JS, Jeffery ED, Chavkin NW, Genet G, Vasavada H, Nelson EA, Sheynkman GM, Humphries MJ, Hirschi KK., Free PMC Article | 06/7/2023 |
SIRT1/FOXO3-mediated autophagy signaling involved in manganese-induced neuroinflammation in microglia. | SIRT1/FOXO3-mediated autophagy signaling involved in manganese-induced neuroinflammation in microglia. Yan D, Yang Y, Lang J, Wang X, Huang Y, Meng J, Wu J, Zeng X, Li H, Ma H, Gao L. | 04/26/2023 |
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice. | Mitochondria-derived H(2)O(2) triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice. Bai H, Fang CW, Shi Y, Zhai S, Jiang A, Li YN, Wang L, Liu QL, Zhou GY, Cao JH, Li J, Yang XK, Qin XJ., Free PMC Article | 04/4/2023 |
FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50. | FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50. Inci G, Warkad MS, Kang BG, Lee NK, Suh HW, Lim SS, Kim J, Kim SC, Lee JY., Free PMC Article | 03/3/2023 |
CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy. | CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy. Zhao C, Li X, Sun G, Liu P, Kong K, Chen X, Yang F, Wang X., Free PMC Article | 11/19/2022 |
MeCP2 inhibits ischemic neuronal injury by enhancing methylation of the FOXO3a promoter to repress the SPRY2-ZEB1 axis. | MeCP2 inhibits ischemic neuronal injury by enhancing methylation of the FOXO3a promoter to repress the SPRY2-ZEB1 axis. Meng L, Feng B, Luan L, Fang Z, Zhao G., Free PMC Article | 09/17/2022 |
Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis. | Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis. Ghosh S, Singh R, Vanwinkle ZM, Guo H, Vemula PK, Goel A, Haribabu B, Jala VR., Free PMC Article | 08/6/2022 |