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    METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit [ Homo sapiens (human) ]

    Gene ID: 56339, updated on 29-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    METTL3-driven m6A modification of lncRNA FAM230B suppresses ferroptosis by modulating miR-27a-5p/BTF3 axis in gastric cancer.

    METTL3-driven m6A modification of lncRNA FAM230B suppresses ferroptosis by modulating miR-27a-5p/BTF3 axis in gastric cancer.
    Cui Y, Pu M, Gong Y, Li R, Wang X, Ye J, Huang H, Liao D, Yang Y, Yin A, Li J, Deng Y, Tian Z, Pu R.

    10/25/2024
    The indispensability of methyltransferase-like 3 in the immune system: from maintaining homeostasis to driving function.

    The indispensability of methyltransferase-like 3 in the immune system: from maintaining homeostasis to driving function.
    Zhang M, Gou Z, Qu Y, Su X., Free PMC Article

    10/25/2024
    METTL3 mediates m6A modification of lncRNA CRNDE to promote ATG10 expression and improve brain ischemia/reperfusion injury through YTHDC1.

    METTL3 mediates m6A modification of lncRNA CRNDE to promote ATG10 expression and improve brain ischemia/reperfusion injury through YTHDC1.
    Yu Z, Xia Y, Li J, Jiang J, Li Y, Li Y, Wang L., Free PMC Article

    10/20/2024
    METTL3/IGF2BP1 influences the development of non-small-cell lung cancer by mediating m6A methylation modification of TRPV1.

    METTL3/IGF2BP1 influences the development of non-small-cell lung cancer by mediating m6A methylation modification of TRPV1.
    Bai W, Xiao G, Xie G, Chen Z, Xu X, Zeng J, Xie J., Free PMC Article

    10/18/2024
    A novel interaction between RNA m[6]A methyltransferase METTL3 and RREB1.

    A novel interaction between RNA m(6)A methyltransferase METTL3 and RREB1.
    Xu J, Sivakumar C, Ryan CW, Rao RC.

    10/16/2024
    METTL3 and IGF2BP1-Mediated m6A Modification of ZHX2 Promotes Tumor Property of Renal Cell Carcinoma.

    METTL3 and IGF2BP1-Mediated m6A Modification of ZHX2 Promotes Tumor Property of Renal Cell Carcinoma.
    Xiao B, Li Y, Yang Y, Chen C, Gong S, Li H, Yao Q, Wang L.

    10/1/2024
    METTL3 Regulates the Translation of Oncogene Myc through m[6]A Modification and Promotes the Occurrence and Development of Cervical Cancer.

    METTL3 Regulates the Translation of Oncogene Myc through m(6)A Modification and Promotes the Occurrence and Development of Cervical Cancer.
    Ma Y, Shi H, Zheng W.

    10/1/2024
    METTL3's role in cervical cancer development through m[6]A modification.

    METTL3's role in cervical cancer development through m(6)A modification.
    Liu Y, Li C, Deng Q, Ren X, Wang H.

    09/18/2024
    METTL3-STAT5B interaction facilitates the co-transcriptional m[6]A modification of mRNA to promote breast tumorigenesis.

    METTL3-STAT5B interaction facilitates the co-transcriptional m(6)A modification of mRNA to promote breast tumorigenesis.
    Bhattarai PY, Kim G, Lim SC, Choi HS.

    09/16/2024
    METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth.

    METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth.
    Wu S, Wang H, Yang Q, Liu Z, Du J, Wang L, Chen S, Lu Q, Yang DH.

    09/9/2024
    Review of METTL3 in colorectal cancer: From mechanisms to the therapeutic potential.

    Review of METTL3 in colorectal cancer: From mechanisms to the therapeutic potential.
    Zhang L, Mao Z, Yin K, Wang S.

    08/22/2024
    METTL3-mediated m[6]A methylation of SLC38A1 stimulates cervical cancer growth.

    METTL3-mediated m(6)A methylation of SLC38A1 stimulates cervical cancer growth.
    Liu HT, Zhao Y, Wang HC, Liu QL.

    08/7/2024
    METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer.

    METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer.
    Wang T, Li X, Tao Y, Wang X, Li L, Liu J., Free PMC Article

    08/5/2024
    METTL3 aggravates cell damage induced by Streptococcus pneumoniae via the NEAT1/CTCF/MUC19 axis.

    METTL3 aggravates cell damage induced by Streptococcus pneumoniae via the NEAT1/CTCF/MUC19 axis.
    Ma DB, Zhang H, Wang XL, Wu QG.

    08/4/2024
    METTL3-modified lncRNA DSCAM-AS1 promotes breast cancer progression through inhibiting ferroptosis.

    METTL3-modified lncRNA DSCAM-AS1 promotes breast cancer progression through inhibiting ferroptosis.
    Yan Z, Liang Z, Luo K, Yu L, Chen C, Yu M, Guo X, Li M.

    07/22/2024
    METTL3-mediated N[6]-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4.

    METTL3-mediated N(6)-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4.
    Zang Y, Tian Z, Wang D, Li Y, Zhang W, Ma C, Liao Z, Gao W, Qian L, Xu X, Jia J, Liu Z., Free PMC Article

    07/22/2024
    METTL3 regulates thyroid cancer differentiation and chemosensitivity by modulating PAX8.

    METTL3 regulates thyroid cancer differentiation and chemosensitivity by modulating PAX8.
    Kang N, Zhao Z, Wang Z, Ning J, Wang H, Zhang W, Ruan X, Gao M, Zheng X., Free PMC Article

    07/18/2024
    N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension.

    N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension.
    Kang K, Xiang J, Zhang X, Xie Y, Zhou M, Zeng L, Zhuang J, Kuang J, Lin Y, Hu B, Xiong Q, Yin Q, Su Q, Liao X, Wang J, Niu Y, Liu C, Tian J, Gou D., Free PMC Article

    07/12/2024
    Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma.

    Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma.
    Guo S, Chen F, Li L, Dou S, Li Q, Huang Y, Li Z, Liu W, Zhang G., Free PMC Article

    07/11/2024
    METTL3 potentiates osteogenic differentiation of bone marrow mesenchymal stem cells via IGF2BP1/m6A/RUNX2.

    METTL3 potentiates osteogenic differentiation of bone marrow mesenchymal stem cells via IGF2BP1/m6A/RUNX2.
    Zhou S, Zhang G, Wang K, Yang Z, Tan Y.

    06/12/2024
    METTL3-mediated ALDH m[6]A methylation regulates the malignant behavior of BMI1[+] HNSCC stem cells.

    METTL3-mediated ALDH m(6)A methylation regulates the malignant behavior of BMI1(+) HNSCC stem cells.
    Chen Z, Chen J, Xu X, Li Q, Zhang C, Li S, Liu L, Cao C, Chen D, He Q.

    06/11/2024
    METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.

    METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.
    Yuan XN, Shao YC, Guan XQ, Liu Q, Chu MF, Yang ZL, Li H, Zhao S, Tian YH, Zhang JW, Wei L.

    06/5/2024
    Negative Regulation of LINC01013 by METTL3 and YTHDF2 Enhances the Osteogenic Differentiation of Senescent Pre-Osteoblast Cells Induced by Hydrogen Peroxide.

    Negative Regulation of LINC01013 by METTL3 and YTHDF2 Enhances the Osteogenic Differentiation of Senescent Pre-Osteoblast Cells Induced by Hydrogen Peroxide.
    Song J, Wang Y, Zhu Z, Wang W, Yang H, Shan Z.

    05/31/2024
    METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis.

    METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis.
    Ouyang P, Li K, Xu W, Chen C, Shi Y, Tian Y, Gong J, Bao Z., Free PMC Article

    04/29/2024
    Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3.

    Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3.
    Li G, Liu H, Yu Y, Wang Q, Yang C, Yan Y, Wang F, Mao Y., Free PMC Article

    04/18/2024
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