Mutation Ter462GlnextTer17 introduces a tail to C-terminus of protein C and causes venous thrombosis. | Mutation Ter462GlnextTer17 introduces a tail to C-terminus of protein C and causes venous thrombosis. Lai Z, Li J, Zhou S, Wu X, Yuan J, Li F, Wu W, Ding Q, Dai J, Wang X, Lu Y, Cai X. | 07/31/2024 |
Analysis of PROC mutations and clinical features in 22 unrelated families with inherited protein C deficiency. | Analysis of PROC mutations and clinical features in 22 unrelated families with inherited protein C deficiency. Xu F, Zhang K, Xu Q, Ye L, Zeng M, Jin Y, Wang M, Yang L. | 02/1/2024 |
Computational analysis of the functional and structural impact of the most deleterious missense mutations in the human Protein C. | Computational analysis of the functional and structural impact of the most deleterious missense mutations in the human Protein C. Farajzadeh-Dehkordi M, Mafakher L, Harifi A, Samiee-Rad F, Rahmani B., Free PMC Article | 01/31/2024 |
Activated Protein C Prevents Neuronal Apoptosis via Protease Activated Receptors 1 and 3. | Activated Protein C Prevents Neuronal Apoptosis via Protease Activated Receptors 1 and 3. Guo H, Liu D, Gelbard H, Cheng T, Insalaco R, Fernández JA, Griffin JH, Zlokovic BV. | 01/3/2024 |
Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3. | Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3. Huckriede JB, Beurskens DMH, Wildhagen KCCA, Reutelingsperger CPM, Wichapong K, Nicolaes GAF. | 12/15/2023 |
Activated protein C, protein S, and tissue factor pathway inhibitor cooperate to inhibit thrombin activation. | Activated protein C, protein S, and tissue factor pathway inhibitor cooperate to inhibit thrombin activation. Li X, Song X, Mahmood DFD, Sim MMS, Bidarian SJ, Wood JP., Free PMC Article | 10/10/2023 |
APC ameliorates idiopathic membranous nephropathy by affecting podocyte apoptosis through the ERK1/2/YB-1/PLA2R1 axis. | APC ameliorates idiopathic membranous nephropathy by affecting podocyte apoptosis through the ERK1/2/YB-1/PLA2R1 axis. Ke B, Shen W, Liao Y, Hu J, Tu W, Fang X., Free PMC Article | 08/9/2023 |
Protein C and S levels in patients with Thalassemia intermedia. | Protein C and S levels in patients with Thalassemia intermedia. Mohammed NS., Free PMC Article | 01/14/2023 |
Pediatric Retinal Detachment in Homozygous Protein C Deficiency: Genetic and Phenotypic Description of a Single Family. | Pediatric Retinal Detachment in Homozygous Protein C Deficiency: Genetic and Phenotypic Description of a Single Family. Alotaibi MD, Albakri AS, Alsulaiman SM. | 05/28/2022 |
[Clinical phenotype and gene mutation analysis of 12 patients with hereditary protein C deficiency in different families]. | [Clinical phenotype and gene mutation analysis of 12 patients with hereditary protein C deficiency in different families]. Xu QY, Yang LL, Xie HX, Jin YH, Li XL, Zhou XX, Liu MN, Wang MS., Free PMC Article | 03/5/2022 |
Activated Protein C Protects against Murine Contact Dermatitis by Suppressing Protease-Activated Receptor 2. | Activated Protein C Protects against Murine Contact Dermatitis by Suppressing Protease-Activated Receptor 2. Xue M, Lin H, Zhao R, Fryer C, March L, Jackson CJ., Free PMC Article | 02/19/2022 |
How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen. | How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen. Peacock RB, McGrann T, Zaragoza S, Komives EA., Free PMC Article | 02/19/2022 |
Protein C Promotor Haplotypes Associated with Large-Artery Atherosclerosis Stroke in Iranian Population. | Protein C Promotor Haplotypes Associated with Large-Artery Atherosclerosis Stroke in Iranian Population. Meshkani SE, Fasihi A, Badakhshan F, Zahedi M, Goudarzian M, Ramazi S. | 02/5/2022 |
The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis. | The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis. Catenacci V, Sheikh F, Patel K, Fox-Robichaud AE., Free PMC Article | 01/29/2022 |
Two heterozygous mutations associated with type I protein C deficiency in two Chinese independent families. | Two heterozygous mutations associated with type I protein C deficiency in two Chinese independent families. Xu Q, Wang M, Jin Y, Liu S, Luo S, Yang L. | 01/22/2022 |
Association between Circulating Protein C Levels and Incident Dementia: The Atherosclerosis Risk in Communities Study. | Association between Circulating Protein C Levels and Incident Dementia: The Atherosclerosis Risk in Communities Study. Tin A, Walker KA, Bressler J, Windham BG, Griswold M, Sullivan K, Wu A, Gottesman R, Fornage M, Coresh J, Sharrett AR, Folsom AR, Mosley TH., Free PMC Article | 11/6/2021 |
MiR-124 and miR-506 are involved in the decline of protein C in children with extra-hepatic portal vein obstruction. | MiR-124 and miR-506 are involved in the decline of protein C in children with extra-hepatic portal vein obstruction. Zhang JS, Li L., Free PMC Article | 10/23/2021 |
Severe Protein C Deficiency due to Novel Biallelic Variants in PROC and Their Phenotype Correlation. | Severe Protein C Deficiency due to Novel Biallelic Variants in PROC and Their Phenotype Correlation. Barg AA, Dardik R, Levin C, Koren A, Levy-Mendelovich S, Pode-Shakked B, Kenet G. | 08/14/2021 |
Genotype-Phenotype Relationships in a Large French Cohort of Subjects with Inherited Protein C Deficiency. | Genotype-Phenotype Relationships in a Large French Cohort of Subjects with Inherited Protein C Deficiency. Alhenc-Gelas M, Plu-Bureau G, Mauge L, Gandrille S, Présot I, GFHT Study Group on Genetic Thrombophilia. | 07/31/2021 |
Protein C deficiency; PROC gene variants in a Danish population. | Protein C deficiency; PROC gene variants in a Danish population. Winther-Larsen A, Kjaergaard AD, Larsen OH, Hvas AM, Nissen PH. | 07/17/2021 |
Burden of rare exome sequence variants in PROC gene is associated with venous thromboembolism: a population-based study. | Burden of rare exome sequence variants in PROC gene is associated with venous thromboembolism: a population-based study. Tang W, Stimson MR, Basu S, Heckbert SR, Cushman M, Pankow JS, Folsom AR, Pankratz N., Free PMC Article | 06/19/2021 |
Recurrent PROC and novel PROS1 mutations in Vietnamese patients diagnosed with idiopathic deep venous thrombosis. | Recurrent PROC and novel PROS1 mutations in Vietnamese patients diagnosed with idiopathic deep venous thrombosis. Do MD, Pham DV, Le LP, Gia Le LH, Minh Tran LB, Dang Huynh MD, Do QM, Vu HA, Nguyen NH, Mai TP. | 06/12/2021 |
Ile73Asn mutation in protein C introduces a new N-linked glycosylation site on the first EGF-domain of protein C and causes thrombosis. | Ile73Asn mutation in protein C introduces a new N-linked glycosylation site on the first EGF-domain of protein C and causes thrombosis. Lu Y, Mehta-D'souza P, Biswas I, Villoutreix BO, Wang X, Ding Q, Rezaie AR., Free PMC Article | 05/8/2021 |
[Genetic and Clinical Characteristics of A Family with Combined PROC and PROS1 Genetic Variants]. | [Genetic and Clinical Characteristics of A Family with Combined PROC and PROS1 Genetic Variants]. Wang X, Sheng GY, Zhang W, Zhao YX, Xia LJ, Jiang M. | 04/13/2021 |
Increase of Neutrophil Activation Markers in Venous Thrombosis-Contribution of Circulating Activated Protein C. | Increase of Neutrophil Activation Markers in Venous Thrombosis-Contribution of Circulating Activated Protein C. Martos L, Oto J, Fernández-Pardo Á, Plana E, Solmoirago MJ, Cana F, Hervás D, Bonanad S, Ferrando F, España F, Navarro S, Medina P., Free PMC Article | 02/20/2021 |