| The Pyroptosis-Related Signature Composed of GSDMC Predicts Prognosis and Contributes to Growth and Metastasis of Hepatocellular Carcinoma. | The Pyroptosis-Related Signature Composed of GSDMC Predicts Prognosis and Contributes to Growth and Metastasis of Hepatocellular Carcinoma.
Li M, Jiang Q, Liu X, Han L, Chen S, Xue R. | 11/8/2023 |
| System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma. | System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma.
Yan C, Niu Y, Li F, Zhao W, Ma L., Free PMC Article | 10/15/2022 |
| High Expression of GSDMC Is Associated with Poor Survival in Kidney Clear Cell Cancer. | High Expression of GSDMC Is Associated with Poor Survival in Kidney Clear Cell Cancer.
Cui YQ, Meng F, Zhan WL, Dai ZT, Liao X., Free PMC Article | 01/22/2022 |
| Association of GSDMC polymorphisms with lumbar disc herniation among Chinese Han population. | Association of GSDMC polymorphisms with lumbar disc herniation among Chinese Han population.
Wu J, Sun Y, Xiong Z, Liu J, Li H, Liu Y, Li B, Jin T. | 06/19/2021 |
| Two GWAS-identified variants are associated with lumbar spinal stenosis and Gasdermin-C expression in Chinese population. | Two GWAS-identified variants are associated with lumbar spinal stenosis and Gasdermin-C expression in Chinese population.
Jiang H, Moro A, Liu Y, Wang J, Meng D, Zhan X, Wei Q., Free PMC Article | 03/20/2021 |
| PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. | PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC., Free PMC Article | 12/12/2020 |
| Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma. | Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma.
Wei J, Xu Z, Chen X, Wang X, Zeng S, Qian L, Yang X, Ou C, Lin W, Gong Z, Yan Y., Free PMC Article | 11/21/2020 |
| These data suggested that TRPV1 may serve an important role in the induction of GSDMC expression by UV and that UVinduced GSDMC expression may be mediated via a calcium/calcineurin/NFATc1 pathway. | Ultraviolet light-induced gasdermin C expression is mediated via TRPV1/calcium/calcineurin/NFATc1 signaling.
Kusumaningrum N, Lee DH, Yoon HS, Park CH, Chung JH. | 01/26/2019 |
| Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways. | Gasdermin C is induced by ultraviolet light and contributes to MMP-1 expression via activation of ERK and JNK pathways.
Kusumaningrum N, Lee DH, Yoon HS, Kim YK, Park CH, Chung JH. | 09/22/2018 |
| Gasdermin C is upregulated by inactivation of Tgfbr2 in the presence of mutated Apc, promoting colorectal cancer cell proliferation. | Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.
Miguchi M, Hinoi T, Shimomura M, Adachi T, Saito Y, Niitsu H, Kochi M, Sada H, Sotomaru Y, Ikenoue T, Shigeyasu K, Tanakaya K, Kitadai Y, Sentani K, Oue N, Yasui W, Ohdan H., Free PMC Article | 06/24/2017 |
| Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers. | Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium.
Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H. | 01/21/2010 |