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    TEX11 testis expressed 11 [ Homo sapiens (human) ]

    Gene ID: 56159, updated on 27-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Novel mutations of TEX11 are associated with non-obstructive azoospermia.

    Novel mutations of TEX11 are associated with non-obstructive azoospermia.
    Song J, Sha Y, Liu X, Zeng X, Zhao X., Free PMC Article

    05/19/2023
    Downregulation of TEX11 promotes S-Phase progression and proliferation in colorectal cancer cells through the FOXO3a/COP1/c-Jun/p21 axis.

    Downregulation of TEX11 promotes S-Phase progression and proliferation in colorectal cancer cells through the FOXO3a/COP1/c-Jun/p21 axis.
    Zhang X, Hu F, Zhu B, Jiao X, Li Y, Wu S, Ren G, Li J, Xie Q, Pan Y, Li H, Zhao L.

    12/3/2022
    Testis-expressed gene 11 inhibits cisplatin-induced DNA damage and contributes to chemoresistance in testicular germ cell tumor.

    Testis-expressed gene 11 inhibits cisplatin-induced DNA damage and contributes to chemoresistance in testicular germ cell tumor.
    Kitayama S, Ikeda K, Sato W, Takeshita H, Kawakami S, Inoue S, Horie K., Free PMC Article

    11/5/2022
    Association of CATSPER1, SPATA16 and TEX11 genes polymorphism with idiopathic azoospermia and oligospermia risk in Iranian population.

    Association of CATSPER1, SPATA16 and TEX11 genes polymorphism with idiopathic azoospermia and oligospermia risk in Iranian population.
    Behvarz M, Rahmani SA, Siasi Torbati E, Danaei Mehrabad S, Bikhof Torbati M., Free PMC Article

    04/30/2022
    Targeted next-generation sequencing panel screening of 668 Chinese patients with non-obstructive azoospermia.

    Targeted next-generation sequencing panel screening of 668 Chinese patients with non-obstructive azoospermia.
    An M, Liu Y, Zhang M, Hu K, Jin Y, Xu S, Wang H, Lu M., Free PMC Article

    01/15/2022
    A new TEX11 mutation causes azoospermia and testicular meiotic arrest.

    A new TEX11 mutation causes azoospermia and testicular meiotic arrest.
    Yu XC, Li MJ, Cai FF, Yang SJ, Liu HB, Zhang HB., Free PMC Article

    12/4/2021
    Zinc transporter mutations linked to acrodermatitis enteropathica disrupt function and cause mistrafficking.

    Zinc transporter mutations linked to acrodermatitis enteropathica disrupt function and cause mistrafficking.
    Kuliyev E, Zhang C, Sui D, Hu J., Free PMC Article

    08/28/2021
    This result suggests that regular expression of TEX11, TEX12, TEX14 and TEX15 is essential for the early stages of spermatogenesis.

    Expression analysis of genes encoding TEX11, TEX12, TEX14 and TEX15 in testis tissues of men with non-obstructive azoospermia.
    Boroujeni PB, Sabbaghian M, Totonchi M, Sodeifi N, Sarkardeh H, Samadian A, Sadighi-Gilani MA, Gourabi H., Free PMC Article

    12/21/2019
    Data identified one novel TEX11 mutation in two brothers. The missense mutation is associated with male infertility, especially azoospermia.

    A novel TEX11 mutation induces azoospermia: a case report of infertile brothers and literature review.
    Sha Y, Zheng L, Ji Z, Mei L, Ding L, Lin S, Wang X, Yang X, Li P., Free PMC Article

    03/2/2019
    Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility.

    RNA immunoprecipitation identifies novel targets of DAZL in human foetal ovary.
    Rosario R, Smith RW, Adams IR, Anderson RA., Free PMC Article

    12/23/2017
    Genetic screening of a large cohort of idiopathic infertile men reveals that TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of azoospermic men.

    TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.
    Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ, Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ., Free PMC Articles: PMC4568952, PMC4568952

    06/4/2016
    TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of non-obstructive azoospermic men.

    TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.
    Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ, Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ., Free PMC Articles: PMC4568952, PMC4568952

    07/7/2015
    hemizygous TEX11 mutations were a common cause of meiotic arrest and azoospermia in infertile men

    X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men.
    Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfilippo J, Kurpisz M, Rajkovic A, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F., Free PMC Article

    06/20/2015
    Observational study of gene-disease association. (HuGE Navigator)

    Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.
    Aston KI, Krausz C, Laface I, Ruiz-Castané E, Carrell DT.

    06/30/2010
    TEX11 was specifically expressed in human testis.

    An abundance of X-linked genes expressed in spermatogonia.
    Wang PJ, McCarrey JR, Yang F, Page DC.

    06/26/2009
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