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    MYDGF myeloid derived growth factor [ Homo sapiens (human) ]

    Gene ID: 56005, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Myeloid-derived growth factor and its effects on cardiovascular and metabolic diseases.

    Myeloid-derived growth factor and its effects on cardiovascular and metabolic diseases.
    Xu J, Song Y, Ding S, Duan W, Xiang G, Wang Z.

    03/29/2024
    Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes.

    Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes.
    Große-Segerath L, Follert P, Behnke K, Ettich J, Buschmann T, Kirschner P, Hartwig S, Lehr S, Korf-Klingebiel M, Eberhard D, Lehwald-Tywuschik N, Al-Hasani H, Knoefel WT, Heinrich S, Levkau B, Wollert KC, Scheller J, Lammert E., Free PMC Article

    03/8/2024
    rhMYDGF Alleviates I/R-induced Kidney Injury by Inhibiting Inflammation and Apoptosis via the Akt Pathway.

    rhMYDGF Alleviates I/R-induced Kidney Injury by Inhibiting Inflammation and Apoptosis via the Akt Pathway.
    Wang J, Ma R, Wang Y, Zhang S, Wang J, Zheng J, Xue W, Ding X., Free PMC Article

    07/27/2023
    Altered peripheral B lymphocyte homeostasis and functions mediated by IL-27 via activating the mammalian target of rapamycin signaling pathway in patients with rheumatoid arthritis.

    Altered peripheral B lymphocyte homeostasis and functions mediated by IL-27 via activating the mammalian target of rapamycin signaling pathway in patients with rheumatoid arthritis.
    Tang Y, Bai Z, Qi J, Lu Z, Ahmad, Wang G, Jin M, Wang B, Chen H, Li X., Free PMC Article

    01/1/2022
    Identification of the correlations between interleukin-27 (IL-27) and immune-inflammatory imbalance in preterm birth.

    Identification of the correlations between interleukin-27 (IL-27) and immune-inflammatory imbalance in preterm birth.
    Ran Y, Huang D, Mei Y, Liu Z, Zhou Y, He J, Zhang H, Yin N, Qi H., Free PMC Article

    12/25/2021
    Hypoxia-induced myeloid derived growth factor promotes hepatocellular carcinoma progression through remodeling tumor microenvironment.

    Hypoxia-induced myeloid derived growth factor promotes hepatocellular carcinoma progression through remodeling tumor microenvironment.
    Wang X, Mao J, Zhou T, Chen X, Tu H, Ma J, Li Y, Ding Y, Yang Y, Wu H, Tang X., Free PMC Article

    08/7/2021
    maintains glucose homeostasis by inducing glucagon-like peptide-1 production and secretion

    Myeloid-Derived Growth Factor Promotes Intestinal Glucagon-Like Peptide-1 Production in Male Mice With Type 2 Diabetes.
    Wang L, Li Y, Guo B, Zhang J, Zhu B, Li H, Ding Y, Meng B, Zhao H, Xiang L, Dong J, Liu M, Zhang J, Xiang L, Xiang G.

    07/18/2020
    MYDGF structure consists of a 10-stranded beta-sandwich with a folding topology showing no similarities to other cytokines or growth factors.X-ray structure of MYDGF identifies its functionally relevant receptor binding epitope.

    Crystal structure and receptor-interacting residues of MYDGF - a protein mediating ischemic tissue repair.
    Ebenhoch R, Akhdar A, Reboll MR, Korf-Klingebiel M, Gupta P, Armstrong J, Huang Y, Frego L, Rybina I, Miglietta J, Pekcec A, Wollert KC, Nar H., Free PMC Article

    04/18/2020
    MYDGF complexed to the KDEL receptor binds cargo via its conserved residues for transport to the endoplasmic reticulum.

    Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum.
    Bortnov V, Tonelli M, Lee W, Lin Z, Annis DS, Demerdash ON, Bateman A, Mitchell JC, Ge Y, Markley JL, Mosher DF., Free PMC Article

    02/29/2020
    Bone marrow-derived monocytes and macrophages produce this protein endogenously to protect and repair the heart after myocardial infarction.

    Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction.
    Korf-Klingebiel M, Reboll MR, Klede S, Brod T, Pich A, Polten F, Napp LC, Bauersachs J, Ganser A, Brinkmann E, Reimann I, Kempf T, Niessen HW, Mizrahi J, Schönfeld HJ, Iglesias A, Bobadilla M, Wang Y, Wollert KC.

    04/11/2015
    Taken together, these data suggest that c19orf10 might be one of the growth factors and potential molecular targets activated in HCC.

    Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma.
    Sunagozaka H, Honda M, Yamashita T, Nishino R, Takatori H, Arai K, Yamashita T, Sakai Y, Kaneko S.

    09/24/2011
    we identified a novel protein, c19orf10 (chromosome 19 open reading frame 10), produced by fibroblast-like synoviocytes

    The identification and characterization of a novel protein, c19orf10, in the synovium.
    Weiler T, Du Q, Krokhin O, Ens W, Standing K, El-Gabalawy H, Wilkins JA., Free PMC Article

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)

    The interleukin-25 gene located in the inflammatory bowel disease (IBD) 4 region: no association with inflammatory bowel disease.
    Büning C, Genschel J, Weltrich R, Lochs H, Schmidt H.

    03/13/2008
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