| MAZ promotes thyroid cancer progression by driving transcriptional reprogram and enhancing ERK1/2 activation. | MAZ promotes thyroid cancer progression by driving transcriptional reprogram and enhancing ERK1/2 activation.
Zeng J, Zhang L, Huang L, Yu X, Han L, Zheng Y, Wang T, Zhang N, Yang M. | 09/23/2024 |
| Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors through ERK1/2 nuclear export. | Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors through ERK1/2 nuclear export.
Daneshmandi S, Yan Q, Choi JE, Katsuta E, MacDonald CR, Goruganthu M, Roberts N, Repasky EA, Singh PK, Attwood K, Wang J, Landesman Y, McCarthy PL, Mohammadpour H., | 09/10/2024 |
| Deubiquitination of CIB1 by USP14 promotes lenvatinib resistance via the PAK1-ERK1/2 axis in hepatocellular carcinoma. | Deubiquitination of CIB1 by USP14 promotes lenvatinib resistance via the PAK1-ERK1/2 axis in hepatocellular carcinoma.
Xu MH, Zheng YM, Liang BG, Xu WX, Cao J, Wang P, Dong ZY, Zhou CH, Sun HC, Ren N, Ke AW, Shen YH., Free PMC Article | 07/18/2024 |
| Ferroptosis-related gene MAPK3 is associated with the neurological outcome after cardiac arrest. | Ferroptosis-related gene MAPK3 is associated with the neurological outcome after cardiac arrest.
Hou HX, Pang L, Zhao L, Xing J., Free PMC Article | 07/2/2024 |
| Ciliogenesis-associated Kinase 1 Promotes Breast Cancer Cell Proliferation and Chemoresistance via Phosphorylating ERK1. | Ciliogenesis-associated Kinase 1 Promotes Breast Cancer Cell Proliferation and Chemoresistance via Phosphorylating ERK1.
He Y, Zhang X, Pan W, Zhang J, Zhu W, Zhang J, Shi J., Free PMC Article | 06/13/2024 |
| ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2. | ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2.
Benatzy Y, Palmer MA, Lütjohann D, Ohno RI, Kampschulte N, Schebb NH, Fuhrmann DC, Snodgrass RG, Brüne B., Free PMC Article | 05/28/2024 |
| PP4R1 promotes glycolysis and gallbladder cancer progression through facilitating ERK1/2 mediated PKM2 nuclear translocation. | PP4R1 promotes glycolysis and gallbladder cancer progression through facilitating ERK1/2 mediated PKM2 nuclear translocation.
He Z, Zhong Y, Lv T, Wang J, Jin Y, Li F, Hu H. | 03/19/2024 |
| AKAP2-anchored extracellular signal-regulated kinase 1 (ERK1) regulates cardiac myofibroblast migration. | AKAP2-anchored extracellular signal-regulated kinase 1 (ERK1) regulates cardiac myofibroblast migration.
Delaunay M, Paterek A, Gautschi I, Scherler G, Diviani D. | 03/5/2024 |
| LncNFYB promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via LncNFYB/ANXA2/ERK1/2 axis. | LncNFYB promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via LncNFYB/ANXA2/ERK1/2 axis.
Xiao S, Ouyang Q, Feng Y, Lu X, Han Y, Ren H, Huang Q, Zhao J, Xiao C, Yang M., Free PMC Article | 02/27/2024 |
| Progestins and breast cancer hallmarks: The role of the ERK1/2 and JNK pathways in estrogen receptor positive breast cancer cells. | Progestins and breast cancer hallmarks: The role of the ERK1/2 and JNK pathways in estrogen receptor positive breast cancer cells.
Louw-du Toit R, Simons M, Africander D. | 02/5/2024 |
| Mir-142-3P regulates MAPK protein family by inhibiting 14-3-3eta to enhance bone marrow mesenchymal stem cells osteogenesis. | Mir-142-3P regulates MAPK protein family by inhibiting 14-3-3η to enhance bone marrow mesenchymal stem cells osteogenesis.
Liu YQ, Xu YC, Shuai ZW., Free PMC Article | 01/3/2024 |
| The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants. | The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants.
Petrosino M, Novak L, Pasquo A, Turina P, Capriotti E, Minicozzi V, Consalvi V, Chiaraluce R., Free PMC Article | 11/1/2023 |
| Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis. | Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.
Liu R, Yin C, Zhao P, Guo B, Ke W, Zheng X, Xie D, Wang Y, Wang G, Jia Y, Gao Y, Hu W, Liu GL, Song Z., Free PMC Article | 10/28/2023 |
| Redundant roles of extra-cellular signal-regulated kinase (ERK) 1 and 2 in the G1-S transition and etoposide-induced G2/M checkpoint in HCT116 cells. | Redundant roles of extra-cellular signal-regulated kinase (ERK) 1 and 2 in the G1-S transition and etoposide-induced G2/M checkpoint in HCT116 cells.
Erdenebaatar P, Gunarta IK, Suzuki R, Odongoo R, Fujii T, Fukunaga R, Kanemaki MT, Yoshioka K. | 10/25/2023 |
| A conserved arginine within the alphaC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities. | A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities.
Soudah N, Baskin A, Smorodinsky-Atias K, Beenstock J, Ganon Y, Hayouka R, Aboraya M, Livnah O, Ilouz R, Engelberg D., Free PMC Article | 10/4/2023 |
| Pathologically high intraocular pressure induces mitochondrial dysfunction through Drp1 and leads to retinal ganglion cell PANoptosis in glaucoma. | Pathologically high intraocular pressure induces mitochondrial dysfunction through Drp1 and leads to retinal ganglion cell PANoptosis in glaucoma.
Zeng Z, You M, Fan C, Rong R, Li H, Xia X., Free PMC Article | 05/28/2023 |
| Reduced G protein signaling despite impaired internalization and beta-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome. | Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
Kumar R, Milanesi S, Szpakowska M, Dotta L, Di Silvestre D, Trotta AM, Bello AM, Giacomelli M, Benedito M, Azevedo J, Pereira A, Cortesao E, Vacchini A, Castagna A, Pinelli M, Moratto D, Bonecchi R, Locati M, Scala S, Chevigné A, Borroni EM, Badolato R., Free PMC Article | 03/10/2023 |
| CircPDIA4 Induces Gastric Cancer Progression by Promoting ERK1/2 Activation and Enhancing Biogenesis of Oncogenic circRNAs. | CircPDIA4 Induces Gastric Cancer Progression by Promoting ERK1/2 Activation and Enhancing Biogenesis of Oncogenic circRNAs.
Shen Y, Zhang N, Chai J, Wang T, Ma C, Han L, Yang M. | 03/7/2023 |
| Role of kisspeptin in decidualization and unexplained recurrent spontaneous abortion via the ERK1/2 signalling pathway. | Role of kisspeptin in decidualization and unexplained recurrent spontaneous abortion via the ERK1/2 signalling pathway.
Zhang S, Xiao Y, Wang Y, Qian C, Zhang R, Liu J, Wang Q, Zhang H. | 02/26/2023 |
| MTHFD2 suppresses glioblastoma progression via the inhibition of ERK1/2 phosphorylation. | MTHFD2 suppresses glioblastoma progression via the inhibition of ERK1/2 phosphorylation.
Huang M, Xue J, Chen Z, Zhou X, Chen M, Sun J, Xu Z, Wang S, Xu H, Du Z, Liu M. | 02/11/2023 |
| A-Kinase Anchor Protein 95 Is Involved in ERK1/2-Elk-1 Signal Transduction in Colon Cancer. | A-Kinase Anchor Protein 95 Is Involved in ERK1/2-Elk-1 Signal Transduction in Colon Cancer.
Kong X, An P, Xu J, Liu W, Lin F, Yang Y., Free PMC Article | 02/4/2023 |
| NONO regulates multiple cytokine production in sepsis via the ERK1/2 signaling pathway. | NONO regulates multiple cytokine production in sepsis via the ERK1/2 signaling pathway.
Niu Y, Xu G, Zhu S, Wei X, Wu C, Zhang R, Chen C, Yan L, Luo H, Deng S, Wu W, Li Y, Liu M, Jiang Y, Zhang X. | 01/28/2023 |
| Tumor Cell-Intrinsic BTLA Receptor Inhibits the Proliferation of Tumor Cells via ERK1/2. | Tumor Cell-Intrinsic BTLA Receptor Inhibits the Proliferation of Tumor Cells via ERK1/2.
Cheng TY, Liu YJ, Yan H, Xi YB, Duan LQ, Wang Y, Zhang TT, Gu YM, Wang XD, Wu CX, Gao S., Free PMC Article | 01/14/2023 |
| Elevated Notch-1 expression promotes the lymph node metastasis of gastric cancer and the Notch-1-PTEN-ERK1/2 signalling axis promotes the progression of gastric cancer. | Elevated Notch-1 expression promotes the lymph node metastasis of gastric cancer and the Notch-1-PTEN-ERK1/2 signalling axis promotes the progression of gastric cancer.
Ma H, Li N, Mo Z. | 10/1/2022 |
| The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis. | The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis.
Guney G, Taşkın MI, Sener N, Tolu E, Dodurga Y, Elmas L, Cetin O, Sarigul C., Free PMC Article | 07/9/2022 |