| RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer. | RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer.
Liu SC, Gong LL, Huang FC, Xu N, Yang KX, Liu XH, Li WL. | 08/17/2023 |
| E3 ubiquitin ligase RNF114 promotes vesicular stomatitis virus replication via inhibiting type I interferon production. | E3 ubiquitin ligase RNF114 promotes vesicular stomatitis virus replication via inhibiting type I interferon production.
Han W, Chen Q, Cui J, Zhao Y, Li M, Li X. | 06/11/2022 |
| RNF114 is a new partner of A2O involved in the regulation of NF-kappaB activity that contributes to the control of signaling pathways modulating T cell-mediated immune response. | The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation.
Rodriguez MS, Egaña I, Lopitz-Otsoa F, Aillet F, Lopez-Mato MP, Dorronsoro A, Lobato-Gil S, Sutherland JD, Barrio R, Trigueros C, Lang V., Free PMC Article | 09/12/2015 |
| XAF1 stimulates HIPK2-mediated Ser-46 phosphorylation of p53 and XAF1 also steps up the termination of p53-mediated cell-cycle arrest by activating ZNF313. | XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313.
Lee MG, Han J, Jeong SI, Her NG, Lee JH, Ha TK, Kang MJ, Ryu BK, Chi SG., Free PMC Article | 04/18/2015 |
| RNF114 over-expression had a promotion effect on T cell activation with an average 43.97% increment and the upregulatory roles showed a dose-dependent effect with 18.44% increment. | Identification of RNF114 as a novel positive regulatory protein for T cell activation.
Yang P, Lu Y, Li M, Zhang K, Li C, Chen H, Tao D, Zhang S, Ma Y. | 01/17/2015 |
| A single nucleotide plymorphism had an association with psoriasis in this Chinese Uygur population: SNP rs495337 in the gene encoding for zinc finger protein 313 (P < 0.001; OR = 0.80) | Genetic variants of the genes encoding zinc finger protein 313 and interleukin-13 confer a risk for psoriasis in a Chinese Uygur population.
Feng YY, Sun LD, Zhang C, Zuo XB, Kang XJ, Wu WD, Zhang DZ, Buwajr, Dilinur, Wu XJ, Zhang XJ, Pu XM. | 05/31/2014 |
| ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.). | ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.).
Han J, Kim YL, Lee KW, Her NG, Ha TK, Yoon S, Jeong SI, Lee JH, Kang MJ, Lee MG, Ryu BK, Baik JH, Chi SG., Free PMC Article | 02/8/2014 |
| Rare disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene have been identified. | Identification of rare, disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene.
Onoufriadis A, Simpson MA, Burden AD, Barker JN, Trembath RC, Capon F. | 05/26/2012 |
| RNF114 regulates a positive feedback loop that enhances double-stranded RNA induced production of type I interferon. | Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis.
Bijlmakers MJ, Kanneganti SK, Barker JN, Trembath RC, Capon F., Free PMC Article | 11/12/2011 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Genome-wide association analysis identifies three psoriasis susceptibility loci.
Stuart PE, Nair RP, Ellinghaus E, Ding J, Tejasvi T, Gudjonsson JE, Li Y, Weidinger S, Eberlein B, Gieger C, Wichmann HE, Kunz M, Ike R, Krueger GG, Bowcock AM, Mrowietz U, Lim HW, Voorhees JJ, Abecasis GR, Weichenthal M, Franke A, Rahman P, Gladman DD, Elder JT., Free PMC Article | 12/5/2010 |
| ZNF313 is controlled at the transcriptional level, and a common mechanism controlling the basal transcription of ZNF313 gene exists. | Sp1 plays an important role in regulating the transcription of ZNF313.
Liao X, Deng W, Lu Y, Tao D, Liu Y, Zhang S, Ma Y. | 11/27/2010 |
| ZNF313 is a novel psoriasis susceptibility gene. | Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.
Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC, Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC., Free PMC Articles: PMC2900900, PMC2900900 | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.
Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC, Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC., Free PMC Articles: PMC2900900, PMC2900900 | 04/16/2008 |