| Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCalpha-dependent manner. | Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner.
Xu Y, Cohen E, Johnson CN, Parent CA, Coulombe PA., Free PMC Article | 09/12/2024 |
| PKCalpha Induced the Generation of Extracellular Vesicles in Activated Platelets to Promote Breast Cancer Metastasis. | PKCα Induced the Generation of Extracellular Vesicles in Activated Platelets to Promote Breast Cancer Metastasis.
Zhao J, Tian H, Zhao X, Lan L, Liu H, Sun Y, Yu F., Free PMC Article | 08/9/2024 |
| Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/beta-catenin signaling by stabilization of protein kinase Calpha. | Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/β-catenin signaling by stabilization of protein kinase Cα.
Gholam Azad M, Hussaini M, Russell TM, Richardson V, Kaya B, Dharmasivam M, Richardson DR., Free PMC Article | 07/29/2024 |
| Activation of PKCalpha participates in the reduction of Ikur in atrial myocytes induced by tumour necrosis factor-alpha. | Activation of PKCα participates in the reduction of Ikur in atrial myocytes induced by tumour necrosis factor-α.
Zhou HS, Peng DW, Lai YY, Li Q, Zhao JF, Deng CY, Yang H, Li T, Wang ZY, Xu YW, Xue YM, Wu SL, Guo HM, Rao F. | 07/26/2024 |
| Cav-1 regulates the bile salt export pump on the canalicular membrane of hepatocytes by PKCalpha-associated signalling under cholesterol stimulation. | Cav-1 regulates the bile salt export pump on the canalicular membrane of hepatocytes by PKCα-associated signalling under cholesterol stimulation.
Pang L, Cui M, Wu S, Kong J., Free PMC Article | 02/9/2024 |
| Histone Methyltransferase NSD2 Activates PKCalpha to Drive Metabolic Reprogramming and Lenalidomide Resistance in Multiple Myeloma. | Histone Methyltransferase NSD2 Activates PKCα to Drive Metabolic Reprogramming and Lenalidomide Resistance in Multiple Myeloma.
Chong PSY, Chooi JY, Lim JSL, Leow ACY, Toh SHM, Azaman I, Koh MY, Teoh PJ, Tan TZ, Chung TH, Chng WJ. | 10/25/2023 |
| Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells. | Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells.
Godoy-Parejo C, Deng C, Xu J, Zhang Z, Ren Z, Ai N, Liu W, Ge W, Deng C, Xu X, Chin YE, Chen G. | 06/16/2023 |
| Crosstalk between protein kinase C alpha and transforming growth factor beta signaling mediated by Runx2 in intestinal epithelial cells. | Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells.
Li X, Kaur N, Albahrani M, Karpf AR, Black AR, Black JD., Free PMC Article | 05/17/2023 |
| Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation. | Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation.
Lorenzen L, Frank D, Schwan C, Grosse R., Free PMC Article | 04/5/2023 |
| PKCalpha interacts with Cav 1.3 calcium channels to promote the Cav 1.2/Cav 1.3 duo tuning Th2 functions. | PKCα interacts with Ca(v) 1.3 calcium channels to promote the Ca(v) 1.2/Ca(v) 1.3 duo tuning Th2 functions.
Giang N, Villeneuve T, Maire K, Mejia JE, Guéry JC, Pelletier L, Savignac M. | 03/6/2023 |
| Lipid-independent activation of a muscle-specific PKCalpha splicing variant. | Lipid-independent activation of a muscle-specific PKCα splicing variant.
Gao C, Gong J, Cao N, Wang Y, Steinberg SF., Free PMC Article | 10/15/2022 |
| PKCalpha phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice. | PKCα phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice.
Wang Y, Du J, Lu S, Li X, Chen Y, Yuan C, Hou ST, Wang Y., Free PMC Article | 07/16/2022 |
| The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion. | The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion.
Hernández-Rojas R, Jiménez-Arellano C, de la Fuente-Granada M, Ordaz-Rosado D, García-Becerra R, Valencia-Mayoral P, Álvarez-Arellano L, Eguía-Aguilar P, Velasco-Velázquez MA, González-Arenas A. | 04/9/2022 |
| PKC-isoform specific regulation of receptor desensitization and KCNQ1/KCNE1 K(+) channel activity by mutant alpha1B-adrenergic receptors. | PKC-isoform specific regulation of receptor desensitization and KCNQ1/KCNE1 K(+) channel activity by mutant α(1B)-adrenergic receptors.
Renkhold L, Kollmann R, Inderwiedenstraße L, Kienitz MC. | 04/9/2022 |
| ATF4/CEMIP/PKCalpha promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells. | ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells.
Yu Y, Liu B, Li X, Lu D, Yang L, Chen L, Li Y, Cheng L, Lv F, Zhang P, Song Y, Xing Y., Free PMC Article | 03/26/2022 |
| Gene-gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol. | Gene-gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol.
Oliveira-Paula GH, Pereira DA, Pinheiro LC, Ferreira GC, Paula-Garcia WN, Garcia LV, Lacchini R, Luizon MR, Tanus-Santos JE. | 02/26/2022 |
| IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Calpha (PKCalpha). | IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Cα (PKCα).
Chen AW, Biggar K, Nygard K, Singal S, Zhao T, Li C, Nathanielsz PW, Jansson T, Gupta MB., Free PMC Article | 01/22/2022 |
| Click chemistry-enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling. | Click chemistry-enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling.
Bumpus TW, Huang S, Tei R, Baskin JM., Free PMC Article | 01/15/2022 |
| Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease. | Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease.
Xie Z, Wang Q, Hu S., Free PMC Article | 01/1/2022 |
| The complexities of PKCalpha signaling in cancer. | The complexities of PKCα signaling in cancer.
Black AR, Black JD., Free PMC Article | 01/1/2022 |
| Identification of Activated Protein Kinase Calpha (PKCalpha) in the Urine of Orthotopic Bladder Cancer Xenograft Model as a Potential Biomarker for the Diagnosis of Bladder Cancer. | Identification of Activated Protein Kinase Cα (PKCα) in the Urine of Orthotopic Bladder Cancer Xenograft Model as a Potential Biomarker for the Diagnosis of Bladder Cancer.
Kawano T, Tachibana Y, Inokuchi J, Kang JH, Murata M, Eto M., Free PMC Article | 10/30/2021 |
| LPA1 Receptor Promotes Progesterone Receptor Phosphorylation through PKCalpha in Human Glioblastoma Cells. | LPA(1) Receptor Promotes Progesterone Receptor Phosphorylation through PKCα in Human Glioblastoma Cells.
Valdés-Rives SA, Arcos-Montoya D, de la Fuente-Granada M, Zamora-Sánchez CJ, Arias-Romero LE, Villamar-Cruz O, Camacho-Arroyo I, Pérez-Tapia SM, González-Arenas A., Free PMC Article | 10/23/2021 |
| Exploring the five different genes associated with PKCalpha in bladder cancer based on gene expression microarray. | Exploring the five different genes associated with PKCα in bladder cancer based on gene expression microarray.
Zhang X, Zhang J, Zhang H, Liu Y, Yin L, Liu X, Li X, Yu X, Yao J, Zhang Z, Kong C., Free PMC Article | 09/25/2021 |
| Protein kinase C fusion proteins are paradoxically loss of function in cancer. | Protein kinase C fusion proteins are paradoxically loss of function in cancer.
Van AN, Kunkel MT, Baffi TR, Lordén G, Antal CE, Banerjee S, Newton AC., Free PMC Article | 09/4/2021 |
| The specific PKC-alpha inhibitor chelerythrine blunts costunolide-induced eryptosis. | The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis.
Ghashghaeinia M, Koralkova P, Giustarini D, Mojzikova R, Fehrenbacher B, Dreischer P, Schaller M, Mrowietz U, Martínez-Ruiz A, Wieder T, Divoky V, Rossi R, Lang F, Köberle M., Free PMC Article | 07/31/2021 |