Increased expression of zinc transporter ZIP4, ZIP11, ZnT1, and ZnT6 predicts poor prognosis in pancreatic cancer. | Increased expression of zinc transporter ZIP4, ZIP11, ZnT1, and ZnT6 predicts poor prognosis in pancreatic cancer. Zhu B, Huo R, Zhi Q, Zhan M, Chen X, Hua ZC. | 10/16/2021 |
There was a significant increase in protein levels of ZnT6 in the prefrontal cortex in Major depression disorder, relative to control subjects. | Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims. Rafalo-Ulinska A, Piotrowska J, Kryczyk A, Opoka W, Sowa-Kucma M, Misztak P, Rajkowska G, Stockmeier CA, Datka W, Nowak G, Szewczyk B., Free PMC Article | 09/23/2017 |
A genetic variant within SLC30A6 has a protective role in the severity of Rheumatoid Arthritis. | A genetic variant within SLC30A6 has a protective role in the severity of rheumatoid arthritis. Adelino JE, Addobbati C, Pontillo A, Fragoso TS, Duarte Â, Crovella S, De Azevedo Silva J, Sandrin-Garcia P. | 09/16/2017 |
results of this study suggested that ZnT6 protein levels are decreased in the spinal cords of sporadic ALS patients. | Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis. Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, Kambe T, Yamada M, Inden M, Hara H, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I. | 08/22/2015 |
The results of this study showed that signi fi cant positive correlations between ZIP1,ZnT1, and ZnT6 in most brain in patient with Alzheimer's disease. | Zinc transporter mRNA levels in Alzheimer's disease postmortem brain. Beyer N, Coulson DT, Heggarty S, Ravid R, Hellemans J, Irvine GB, Johnston JA. | 08/18/2012 |
our results suggest that alterations in Zn transport proteins ZnT-1, ZnT-4 and ZnT-6 may contribute to the pathology observed in preclinical Alzheimer's disease subjects before onset of clinical symptoms | Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain. Lyubartseva G, Smith JL, Markesbery WR, Lovell MA., Free PMC Article | 08/16/2010 |
The cytosolic C-terminal tail of ZnT5 is important for its interaction with ZnT6 as a heterodimer. | Demonstration and characterization of the heterodimerization of ZnT5 and ZnT6 in the early secretory pathway. Fukunaka A, Suzuki T, Kurokawa Y, Yamazaki T, Fujiwara N, Ishihara K, Migaki H, Okumura K, Masuda S, Yamaguchi-Iwai Y, Nagao M, Kambe T., Free PMC Article | 01/21/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ. Polymorphisms in mitochondrial genes and prostate cancer risk. Wang L, McDonnell SK, Hebbring SJ, Cunningham JM, St Sauver J, Cerhan JR, Isaya G, Schaid DJ, Thibodeau SN. | 09/20/2009 |
Data show that ZNT6 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. | Abundant expression of zinc transporters in the amyloid plaques of Alzheimer's disease brain. Zhang LH, Wang X, Stoltenberg M, Danscher G, Huang L, Wang ZY. | 01/21/2010 |
hZnT-6 is up-regulated in response to cellular zinc depletion in Raji & THP-1 cells. | Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9. Overbeck S, Uciechowski P, Ackland ML, Ford D, Rink L. | 01/21/2010 |
Our results show that Zn transporter-4 and Zn transporter-6 are significantly (P<0.05) increased in hippocampus/parahippocampal gyrus of early Alzheimer's disease and Alzheimer's disease subjects. | Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. Smith JL, Xiong S, Markesbery WR, Lovell MA. | 01/21/2010 |