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    NAT10 N-acetyltransferase 10 [ Homo sapiens (human) ]

    Gene ID: 55226, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    N-acetyltransferase 10 is implicated in the pathogenesis of cycling T cell-mediated autoimmune and inflammatory disorders in mice.

    N-acetyltransferase 10 is implicated in the pathogenesis of cycling T cell-mediated autoimmune and inflammatory disorders in mice.
    Li WP, Mao XT, Xie JH, Li JY, Liu BQ, Wu LX, Yang B, Li YY, Jin J., Free PMC Article

    11/6/2024
    NAT10-mediated ac[4]C acetylation of TFRC promotes sepsis-induced pulmonary injury through regulating ferroptosis.

    NAT10-mediated ac(4)C acetylation of TFRC promotes sepsis-induced pulmonary injury through regulating ferroptosis.
    Xing P, Zhou M, Sun J, Wang D, Huang W, An P., Free PMC Article

    10/30/2024
    Lactylation of NAT10 promotes N[4]-acetylcytidine modification on tRNA[Ser-CGA-1-1] to boost oncogenic DNA virus KSHV reactivation.

    Lactylation of NAT10 promotes N(4)-acetylcytidine modification on tRNA(Ser-CGA-1-1) to boost oncogenic DNA virus KSHV reactivation.
    Yan Q, Zhou J, Gu Y, Huang W, Ruan M, Zhang H, Wang T, Wei P, Chen G, Li W, Lu C., Free PMC Article

    10/8/2024
    NAT10 Promotes Prostate Cancer Growth and Metastasis by Acetylating mRNAs of HMGA1 and KRT8.

    NAT10 Promotes Prostate Cancer Growth and Metastasis by Acetylating mRNAs of HMGA1 and KRT8.
    Li KJ, Hong Y, Yu YZ, Xie Z, Lv DJ, Wang C, Xie T, Chen H, Chen ZS, Zeng J, Zhao SC., Free PMC Article

    10/7/2024
    NAT10 promotes synovial aggression by increasing the stability and translation of N4-acetylated PTX3 mRNA in rheumatoid arthritis.

    NAT10 promotes synovial aggression by increasing the stability and translation of N4-acetylated PTX3 mRNA in rheumatoid arthritis.
    Liu D, Kuang Y, Chen S, Li R, Su F, Zhang S, Qiu Q, Lin S, Shen C, Liu Y, Liang L, Wang J, Xu H, Xiao Y.

    10/7/2024
    NAT10 Overexpression Promotes Tumorigenesis and Epithelial-Mesenchymal Transition Through AKT Pathway in Gastric Cancer.

    NAT10 Overexpression Promotes Tumorigenesis and Epithelial-Mesenchymal Transition Through AKT Pathway in Gastric Cancer.
    Song S, Li B, Jin X, Li H, Wang H, Wang F, He Y, Zhang C.

    09/29/2024
    N-acetyltransferase 10 facilitates tumorigenesis of diffuse large B-cell lymphoma by regulating AMPK/mTOR signalling through N4-acetylcytidine modification of SLC30A9.

    N-acetyltransferase 10 facilitates tumorigenesis of diffuse large B-cell lymphoma by regulating AMPK/mTOR signalling through N4-acetylcytidine modification of SLC30A9.
    Ding M, Yu Z, Lu T, Hu S, Zhou X, Wang X., Free PMC Article

    07/26/2024
    Dissecting the oncogenic properties of essential RNA-modifying enzymes: a focus on NAT10.

    Dissecting the oncogenic properties of essential RNA-modifying enzymes: a focus on NAT10.
    Dalhat MH, Narayan S, Serio H, Arango D.,

    05/6/2024
    NAT10-mediated mRNA N4-acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression.

    NAT10-mediated mRNA N4-acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression.
    Zhao CC, Sun X, Chen J, Geng BD., Free PMC Article

    04/11/2024
    N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration.

    N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration.
    Ma W, Tian Y, Shi L, Liang J, Ouyang Q, Li J, Chen H, Sun H, Ji H, Liu X, Huang W, Gao X, Jin X, Wang X, Liu Y, Yu Y, Guo X, Tian Y, Yang F, Li F, Wang N, Cai B., Free PMC Article

    03/13/2024
    N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modi fi cation of the lymphocyte antigen six family member E (LY6E) mRNA.

    N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA.
    Dang Y, Li J, Li Y, Wang Y, Zhao Y, Zhao N, Li W, Zhang H, Ye C, Ma H, Zhang L, Liu H, Dong Y, Yao M, Lei Y, Xu Z, Zhang F, Ye W., Free PMC Article

    02/15/2024
    N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling.

    N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling.
    Hu Z, Lu Y, Cao J, Lin L, Chen X, Zhou Z, Pu J, Chen G, Ma X, Deng Q, Jin Y, Jiang L, Li Y, Li T, Liu J, Zhu S., Free PMC Article

    02/6/2024
    RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac[4]C modification.

    RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac(4)C modification.
    Wang X, Ling R, Peng Y, Qiu W, Chen D., Free PMC Article

    01/29/2024
    CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression.

    CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression.
    Shuai Y, Zhang H, Liu C, Wang J, Jiang Y, Sun J, Gao X, Bo X, Xiao X, Liao X, Huang C, Chen H, Jiang G., Free PMC Article

    01/26/2024
    Decreased expression of NAT10 in peripheral blood mononuclear cells from new-onset ankylosing spondylitis and its clinical significance.

    Decreased expression of NAT10 in peripheral blood mononuclear cells from new-onset ankylosing spondylitis and its clinical significance.
    Luo Q, Zhu J, Wang S, Fu P, Fu B, Huang Z, Li J., Free PMC Article

    01/5/2024
    NAT10 Is Involved in Cardiac Remodeling Through ac4C-Mediated Transcriptomic Regulation.

    NAT10 Is Involved in Cardiac Remodeling Through ac4C-Mediated Transcriptomic Regulation.
    Shi J, Yang C, Zhang J, Zhao K, Li P, Kong C, Wu X, Sun H, Zheng R, Sun W, Chen L, Kong X.

    12/22/2023
    NAT10 Promotes Malignant Progression of Lung Cancer via the NF-kappaB Signaling Pathway.

    NAT10 Promotes Malignant Progression of Lung Cancer via the NF-κB Signaling Pathway.
    Liu X, Liu X, Zhuo C, Shen J, Lu K, Sha M, Ye J, Huang J, Han H, Yu H.

    12/18/2023
    NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.

    NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
    Chen X, Hao Y, Liu Y, Zhong S, You Y, Ao K, Chong T, Luo X, Yin M, Ye M, He H, Lu A, Chen J, Li X, Zhang J, Guo X., Free PMC Article

    11/18/2023
    N-acetyltransferase 10 promotes the progression of oral squamous cell carcinoma through N4-acetylcytidine RNA acetylation of MMP1 mRNA.

    N-acetyltransferase 10 promotes the progression of oral squamous cell carcinoma through N4-acetylcytidine RNA acetylation of MMP1 mRNA.
    Liu Y, Huang H, Zhang CB, Fan HN., Free PMC Article

    11/16/2023
    NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA.

    NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA.
    Li Z, Li D, Yang T, Yao C., Free PMC Article

    11/15/2023
    N4-acetylcytidine-dependent GLMP mRNA stabilization by NAT10 promotes head and neck squamous cell carcinoma metastasis and remodels tumor microenvironment through MAPK/ERK signaling pathway.

    N4-acetylcytidine-dependent GLMP mRNA stabilization by NAT10 promotes head and neck squamous cell carcinoma metastasis and remodels tumor microenvironment through MAPK/ERK signaling pathway.
    Liu Y, Wang X, Liu Y, Yang J, Mao W, Feng C, Wu X, Chen X, Chen L, Dong P., Free PMC Article

    11/7/2023
    Activated SIRT1 contributes to DPT-induced glioma cell parthanatos by upregulation of NOX2 and NAT10.

    Activated SIRT1 contributes to DPT-induced glioma cell parthanatos by upregulation of NOX2 and NAT10.
    Liang SP, Wang XZ, Piao MH, Chen X, Wang ZC, Li C, Wang YB, Lu S, He C, Wang YL, Chi GF, Ge PF., Free PMC Article

    10/12/2023
    NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells.

    NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells.
    Liu R, Wubulikasimu Z, Cai R, Meng F, Cui Q, Zhou Y, Li Y., Free PMC Article

    09/13/2023
    NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K/AKT signaling pathway through ac4C modification.

    NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K/AKT signaling pathway through ac4C modification.
    Cui Z, Xu Y, Wu P, Lu Y, Tao Y, Zhou C, Cui R, Li J, Han R.

    09/11/2023
    NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer.

    NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer.
    Wei W, Zhang S, Han H, Wang X, Zheng S, Wang Z, Yang C, Wang L, Ma J, Guo S, Wang J, Liu L, Choe J, Lin S.

    09/8/2023
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