| Promoter hypermethylation as a novel regulator of ANO1 expression and function in prostate cancer bone metastasis. | Promoter hypermethylation as a novel regulator of ANO1 expression and function in prostate cancer bone metastasis.
Shin Y, Kim S, An W., Free PMC Article | 05/29/2024 |
| Ano1 regulates embryo transport by modulating intracellular calcium levels in oviduct smooth muscle. | Ano1 regulates embryo transport by modulating intracellular calcium levels in oviduct smooth muscle.
Liu XM, Li J, Chen D, Li H, Qin XY, Wang YX, Gu YZ, Li N, Zhou LG, Feng M. | 04/16/2024 |
| TMEM16A enhances the activity of the Cdc42-NWASP signaling pathway to promote invasion and metastasis in oral squamous cell carcinoma. | TMEM16A enhances the activity of the Cdc42-NWASP signaling pathway to promote invasion and metastasis in oral squamous cell carcinoma.
Ji J, Zhou Z, Luo Q, Zhu Y, Wang R, Liu Y. | 03/1/2024 |
| High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer. | High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer.
Zhang G, Shu Z, Yu J, Li J, Yi P, Wu B, Deng D, Yan S, Li Y, Ren D, Hou Y, Lan C., Free PMC Article | 02/20/2024 |
| The TMEM16A channel as a potential therapeutic target in vascular disease. | The TMEM16A channel as a potential therapeutic target in vascular disease.
Al-Hosni R, Kaye R, Choi CS, Tammaro P., Free PMC Article | 02/1/2024 |
| Anoctamin-1 is induced by TGF-beta and contributes to lung myofibroblast differentiation. | Anoctamin-1 is induced by TGF-β and contributes to lung myofibroblast differentiation.
Reed EB, Orbeta S, Miao BA, Sitikov A, Chen B, Levitan I, Solway J, Mutlu GM, Fang Y, Mongin AA, Dulin NO. | 01/12/2024 |
| Function and Regulation of the Calcium-Activated Chloride Channel Anoctamin 1 (TMEM16A). | Function and Regulation of the Calcium-Activated Chloride Channel Anoctamin 1 (TMEM16A).
Arreola J, Pérez-Cornejo P, Segura-Covarrubias G, Corral-Fernández N, León-Aparicio D, Guzmán-Hernández ML. | 01/8/2024 |
| The Anion Channel TMEM16a/Ano1 Modulates CFTR Activity, but Does Not Function as an Apical Anion Channel in Colonic Epithelium from Cystic Fibrosis Patients and Healthy Individuals. | The Anion Channel TMEM16a/Ano1 Modulates CFTR Activity, but Does Not Function as an Apical Anion Channel in Colonic Epithelium from Cystic Fibrosis Patients and Healthy Individuals.
Salari A, Xiu R, Amiri M, Pallenberg ST, Schreiber R, Dittrich AM, Tümmler B, Kunzelmann K, Seidler U., Free PMC Article | 09/30/2023 |
| Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease. | Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease.
Pinard A, Ye W, Fraser SM, Rosenfeld JA, Pichurin P, Hickey SE, Guo D, Cecchi AC, Boerio ML, Guey S, Aloui C, Lee K, Kraemer M, Alyemni SO, University of Washington Center for Mendelian Genomics, Bamshad MJ, Nickerson DA, Tournier-Lasserve E, Haider S, Jin SC, Smith ER, Kahle KT, Jan LY, He M, Milewicz DM., Free PMC Article | 09/7/2023 |
| ANO1-Mediated Inhibition of Cancer Ferroptosis Confers Immunotherapeutic Resistance through Recruiting Cancer-Associated Fibroblasts. | ANO1-Mediated Inhibition of Cancer Ferroptosis Confers Immunotherapeutic Resistance through Recruiting Cancer-Associated Fibroblasts.
Jiang F, Jia K, Chen Y, Ji C, Chong X, Li Z, Zhao F, Bai Y, Ge S, Gao J, Zhang X, Li J, Shen L, Zhang C., Free PMC Article | 08/30/2023 |
| Dysregulation of TMEM16A impairs oviductal transport of embryos. | Dysregulation of TMEM16A impairs oviductal transport of embryos.
Ning N, Luo D, Xia W, Mou G, Zhao J, Zhang J, Li C, Wang H, Li J. | 08/30/2023 |
| TMEM16A partners with mTOR to influence pathways of cell survival, proliferation, and migration in cholangiocarcinoma. | TMEM16A partners with mTOR to influence pathways of cell survival, proliferation, and migration in cholangiocarcinoma.
Kulkarni S, Li Q, Singhi AD, Liu S, Monga SP, Feranchak AP., | 07/12/2023 |
| ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis. | ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis.
Deng CM, Zhang GG, Liu QW, Xu JJ, Liu ZC, Yang J, Xu TY, Li ZG, Zhang F, Li B. | 06/7/2023 |
| The role of Transmembrane Protein 16A (TMEM16A) in pulmonary hypertension. | The role of Transmembrane Protein 16A (TMEM16A) in pulmonary hypertension.
Yuan L, Tang Y, Yin L, Lin X, Luo Z, Wang S, Li J, Liang P, Jiang B. | 06/5/2023 |
| TRPV3-ANO1 interaction positively regulates wound healing in keratinocytes. | TRPV3-ANO1 interaction positively regulates wound healing in keratinocytes.
Yamanoi Y, Lei J, Takayama Y, Hosogi S, Marunaka Y, Tominaga M., Free PMC Article | 02/4/2023 |
| Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension. | Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension.
Jimenez C, Hawn MB, Akin E, Leblanc N. | 12/17/2022 |
| Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line. | Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line.
Jaboreck MC, Lühmann JL, Mielenz M, Stanke F, Göhring G, Martin U, Olmer R, Merkert S. | 10/29/2022 |
| DOG1 overexpression is associated with mismatch repair deficiency and BRAF mutations but unrelated to cancer progression in colorectal cancer. | DOG1 overexpression is associated with mismatch repair deficiency and BRAF mutations but unrelated to cancer progression in colorectal cancer.
Jansen K, Kluth M, Blessin NC, Hube-Magg C, Neipp M, Mofid H, Lárusson H, Daniels T, Isbert C, Coerper S, Ditterich D, Rupprecht H, Goetz A, Bernreuther C, Sauter G, Uhlig R, Wilczak W, Simon R, Steurer S, Burandt E, Perez D, Izbicki JR, Jacobsen F, Clauditz TS, Marx AH, Krech T. | 10/15/2022 |
| Anticancer effect of verteporfin on non-small cell lung cancer via downregulation of ANO1. | Anticancer effect of verteporfin on non-small cell lung cancer via downregulation of ANO1.
Jeong SB, Das R, Kim DH, Lee S, Oh HI, Jo S, Lee Y, Kim J, Park S, Choi DK, Moon UY, Kwon OB, Namkung W, Lee S, Cho BC, Woo J, Seo Y. | 09/17/2022 |
| Anoctamin 1 Inhibition Suppresses Cystogenesis by Enhancing Ciliogenesis and the Ciliary Dosage of Polycystins. | Anoctamin 1 Inhibition Suppresses Cystogenesis by Enhancing Ciliogenesis and the Ciliary Dosage of Polycystins.
Xu T, Chen M, Xu Q, Xue C, Fu L, Ling K, Hu J, Mei C. | 07/30/2022 |
| TMEM16A overexpression indicates poor prognosis in colorectal cancer patients. | TMEM16A overexpression indicates poor prognosis in colorectal cancer patients.
Liu JJ, He F, Guo SB. | 07/23/2022 |
| Involvement of TMEM16A/ANO1 upregulation in the oncogenesis of colorectal cancer. | Involvement of TMEM16A/ANO1 upregulation in the oncogenesis of colorectal cancer.
Yan Y, Ding X, Han C, Gao J, Liu Z, Liu Y, Wang K. | 04/16/2022 |
| TMEM16A Protein: Calcium-Binding Site and its Activation Mechanism. | TMEM16A Protein: Calcium-Binding Site and its Activation Mechanism.
Ji W, Shi D, Shi S, Yang X, Chen Y, An H, Pang C. | 02/12/2022 |
| Activation of TMEM16A Ca(2+)-activated Cl(-) channels by ROCK1/moesin promotes breast cancer metastasis. | Activation of TMEM16A Ca(2+)-activated Cl(-) channels by ROCK1/moesin promotes breast cancer metastasis.
Luo S, Wang H, Bai L, Chen Y, Chen S, Gao K, Wang H, Wu S, Song H, Ma K, Liu M, Yao F, Fang Y, Xiao Q., Free PMC Article | 01/22/2022 |
| Molecular dynamics simulation of TMEM16A channel: Linking structure with gating. | Molecular dynamics simulation of TMEM16A channel: Linking structure with gating.
Shi S, Pang C, Ren S, Sun F, Ma B, Guo S, Li J, Chen Y, An H. | 01/1/2022 |