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    PPIA peptidylprolyl isomerase A [ Homo sapiens (human) ]

    Gene ID: 5478, updated on 6-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PPIA dictates NRF2 stability to promote lung cancer progression.

    PPIA dictates NRF2 stability to promote lung cancer progression.
    Lu W, Cui J, Wang W, Hu Q, Xue Y, Liu X, Gong T, Lu Y, Ma H, Yang X, Feng B, Wang Q, Zhang N, Xu Y, Liu M, Nussinov R, Cheng F, Ji H, Huang J., Free PMC Article

    06/13/2024
    Secreted cyclophilin A is non-genotoxic but acts as a tumor promoter.

    Secreted cyclophilin A is non-genotoxic but acts as a tumor promoter.
    Kalinina A, Tilova L, Kirsanov K, Lesovaya E, Zhidkova E, Fetisov T, Ilyinskaya G, Yakubovskaya M, Kazansky D, Khromykh L.

    12/21/2023
    Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus.

    Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus.
    Padron A, Prakash P, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C., Free PMC Article

    12/6/2023
    Bioinformatics analysis and experimental validation of tumorigenic role of PPIA in gastric cancer.

    Bioinformatics analysis and experimental validation of tumorigenic role of PPIA in gastric cancer.
    Liu J, Wang Y, Zhao Z, Ge Y., Free PMC Article

    11/21/2023
    New Insights into Dyskerin-CypA Interaction: Implications for X-Linked Dyskeratosis Congenita and Beyond.

    New Insights into Dyskerin-CypA Interaction: Implications for X-Linked Dyskeratosis Congenita and Beyond.
    Belli V, Maiello D, Di Lorenzo C, Furia M, Vicidomini R, Turano M., Free PMC Article

    10/6/2023
    TRIM5alpha restricts poxviruses and is antagonized by CypA and the viral protein C6.

    TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6.
    Zhao Y, Lu Y, Richardson S, Sreekumar M, Albarnaz JD, Smith GL., Free PMC Article

    08/27/2023
    A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity.

    A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity.
    Schatz M, Marty L, Ounadjela C, Tong PBV, Cardace I, Mettling C, Milhiet PE, Costa L, Godefroy C, Pugnière M, Guichou JF, Mesnard JM, Blaise M, Beaumelle B., Free PMC Article

    05/19/2023
    Cyclophilin A accelerates SiO2-induced macrophage foaming.

    Cyclophilin A accelerates SiO(2)-induced macrophage foaming.
    Liu H, He H, Tian Y, Cui J, Wang S, Wang H.

    02/23/2023
    Cyclophilin A associates with and regulates the activity of ZAP70 in TCR/CD3-stimulated T cells.

    Cyclophilin A associates with and regulates the activity of ZAP70 in TCR/CD3-stimulated T cells.
    Anto NP, Arya AK, Muraleedharan A, Shaik J, Nath PR, Livneh E, Sun Z, Braiman A, Isakov N., Free PMC Article

    12/17/2022
    Clinical and Prognostic Value of PPIA, SQSTM1, and CCL20 in Hepatocellular Carcinoma Patients by Single-Cell Transcriptome Analysis.

    Clinical and Prognostic Value of PPIA, SQSTM1, and CCL20 in Hepatocellular Carcinoma Patients by Single-Cell Transcriptome Analysis.
    Mou L, Jia C, Wu Z, Xin B, Liang Zhen CA, Wang B, Ni Y, Pu Z., Free PMC Article

    10/22/2022
    TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation.

    TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation.
    Franko N, Vrščaj LA, Zore T, Ostanek B, Marc J, Lojk J., Free PMC Article

    04/30/2022
    Cyclophilin A Is Not Acetylated at Lysine-82 and Lysine-125 in Resting and Stimulated Platelets.

    Cyclophilin A Is Not Acetylated at Lysine-82 and Lysine-125 in Resting and Stimulated Platelets.
    Rosa A, Butt E, Hopper CP, Loroch S, Bender M, Schulze H, Sickmann A, Vorlova S, Seizer P, Heinzmann D, Zernecke A., Free PMC Article

    03/19/2022
    Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia.

    Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia.
    Pasetto L, Grassano M, Pozzi S, Luotti S, Sammali E, Migazzi A, Basso M, Spagnolli G, Biasini E, Micotti E, Cerovic M, Carli M, Forloni G, De Marco G, Manera U, Moglia C, Mora G, Traynor BJ, Chiò A, Calvo A, Bonetto V., Free PMC Article

    02/26/2022
    Cyclophilin A: a possible host modulator in Chandipura virus infection.

    Cyclophilin A: a possible host modulator in Chandipura virus infection.
    Pavitrakar DV, Atre NM, Tripathy AS, Shil P., Free PMC Article

    10/16/2021
    Single-nucleotide Polymorphism rs17860041 A/C in the Promoter of the PPIA Gene is Associated with Susceptibility to Kawasaki Disease in Chinese Children.

    Single-nucleotide Polymorphism rs17860041 A/C in the Promoter of the PPIA Gene is Associated with Susceptibility to Kawasaki Disease in Chinese Children.
    Shi R, Luo Y, Li S, Kong M, Liu X, Yu M, Wu J, Huang L, Yang Z.

    10/2/2021
    Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner.

    Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner.
    Zhong Z, Ning J, Boggs EA, Jang S, Wallace C, Telmer C, Bruchez MP, Ahn J, Engelman AN, Zhang P, Watkins SC, Ambrose Z., Free PMC Article

    10/2/2021
    Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with preeclampsia: a preliminary case-control study.

    Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with preeclampsia: a preliminary case-control study.
    Celik S, Soyer Çalışkan C.

    09/11/2021
    CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma.

    CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma.
    Sakamoto M, Miyagaki T, Kamijo H, Oka T, Boki H, Takahashi-Shishido N, Suga H, Sugaya M, Sato S., Free PMC Article

    08/21/2021
    Cyclophilins A and B oppositely regulate renal tubular epithelial cell phenotype.

    Cyclophilins A and B oppositely regulate renal tubular epithelial cell phenotype.
    Sarró E, Durán M, Rico A, Bou-Teen D, Fernández-Majada V, Croatt AJ, Nath KA, Salcedo MT, Gundelach JH, Batlle D, Bram RJ, Meseguer A., Free PMC Article

    08/14/2021
    Cyclophilin A Inhibitor Debio-025 Targets Crk, Reduces Metastasis, and Induces Tumor Immunogenicity in Breast Cancer.

    Cyclophilin A Inhibitor Debio-025 Targets Crk, Reduces Metastasis, and Induces Tumor Immunogenicity in Breast Cancer.
    Davra V, Saleh T, Geng K, Kimani S, Mehta D, Kasikara C, Smith B, Colangelo NW, Ciccarelli B, Li H, Azzam EI, Kalodimos CG, Birge RB, Kumar S., Free PMC Article

    07/3/2021
    Levels of S100 calcium binding protein B (S100B), neuron-specific enolase (NSE), and cyclophilin A (CypA) in the serum of patients with severe craniocerebral injury and multiple injuries combined with delirium transferred from the ICU and their prognostic value.

    Levels of S100 calcium binding protein B (S100B), neuron-specific enolase (NSE), and cyclophilin A (CypA) in the serum of patients with severe craniocerebral injury and multiple injuries combined with delirium transferred from the ICU and their prognostic value.
    Gao Y, Duan J, Ji H, Lu W.

    06/26/2021
    Variations in Trim5alpha and Cyclophilin A genes among HIV-1 elite controllers and non controllers in Uganda: a laboratory-based cross-sectional study.

    Variations in Trim5α and Cyclophilin A genes among HIV-1 elite controllers and non controllers in Uganda: a laboratory-based cross-sectional study.
    Amanya SB, Nyiro B, Waswa F, Obura B, Nakaziba R, Nabulime E, Katabazi AF, Nabatanzi R, Bayiyana A, Mboowa G, Kayongo A, Wayengera M, Sande OJ., Free PMC Article

    06/26/2021
    Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.

    Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.
    Babu M, Favretto F, de Opakua AI, Rankovic M, Becker S, Zweckstetter M., Free PMC Article

    06/19/2021
    Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.

    Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.
    Rath D, von Ungern-Sternberg S, Heinzmann D, Sigle M, Monzien M, Horstmann K, Schaeffeler E, Winter S, Müller K, Groga-Bada P, Zdanyte M, Borst O, Zernecke A, Gawaz M, Martus P, Schwab M, Geisler T, Seizer P.

    06/12/2021
    Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.

    Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.
    Xue C, Senchanthisai S, Sowden M, Pang J, White RJ, Berk BC., Free PMC Article

    05/1/2021
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