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    PPARG peroxisome proliferator activated receptor gamma [ Homo sapiens (human) ]

    Gene ID: 5468, updated on 15-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Exploring the molecular pathways of the activation process in PPARgamma recurrent bladder cancer mutants.

    Exploring the molecular pathways of the activation process in PPARγ recurrent bladder cancer mutants.
    de Oliveira VM, Malospirito CC, da Silva FB, Videira NB, Dias MMG, Sanches MN, Leite VBP, Figueira ACM.

    10/31/2024
    HER2 overexpression in urothelial carcinoma with GATA3 and PPARG copy number gains.

    HER2 overexpression in urothelial carcinoma with GATA3 and PPARG copy number gains.
    Zhu X, Chan E, Turski ML, Mendez CE, Hsu SC, Kumar V, Shipp C, Jindal T, Chang K, Onodera C, Devine WP, Grenert JP, Stohr BA, Ding CC, Stachler MD, Quigley DA, Feng FY, Chu CE, Porten SP, Chou J, Friedlander TW, Koshkin VS., Free PMC Article

    09/11/2024
    Bifidobacterium bifidum Strain BB1 Inhibits Tumor Necrosis Factor-alpha-Induced Increase in Intestinal Epithelial Tight Junction Permeability via Toll-Like Receptor-2/Toll-Like Receptor-6 Receptor Complex-Dependent Stimulation of Peroxisome Proliferator-Activated Receptor gamma and Suppression of NF-kappaB p65.

    Bifidobacterium bifidum Strain BB1 Inhibits Tumor Necrosis Factor-α-Induced Increase in Intestinal Epithelial Tight Junction Permeability via Toll-Like Receptor-2/Toll-Like Receptor-6 Receptor Complex-Dependent Stimulation of Peroxisome Proliferator-Activated Receptor γ and Suppression of NF-κB p65.
    Abdulqadir R, Al-Sadi R, Haque M, Gupta Y, Rawat M, Ma TY.,

    08/30/2024
    The Loss of PPARgamma Expression and Signaling Is a Key Feature of Cutaneous Actinic Disease and Squamous Cell Carcinoma: Association with Tumor Stromal Inflammation.

    The Loss of PPARγ Expression and Signaling Is a Key Feature of Cutaneous Actinic Disease and Squamous Cell Carcinoma: Association with Tumor Stromal Inflammation.
    Konger RL, Xuei X, Derr-Yellin E, Fang F, Gao H, Liu Y., Free PMC Article

    08/29/2024
    Deletion of CD44 promotes adipogenesis by regulating PPARgamma and cell cycle-related pathways.

    Deletion of CD44 promotes adipogenesis by regulating PPARγ and cell cycle-related pathways.
    Weng X, Jiang H, Walker DJ, Zhou H, Lin D, Wang J, Kang L., Free PMC Article

    08/27/2024
    Identification and experimental validation of immune-related gene PPARG is involved in ulcerative colitis.

    Identification and experimental validation of immune-related gene PPARG is involved in ulcerative colitis.
    Li Y, Yan F, Xiang J, Wang W, Xie K, Luo L.

    08/22/2024
    Association between genetically proxied PPARG activation and psoriasis vulgaris: a Mendelian randomization study.

    Association between genetically proxied PPARG activation and psoriasis vulgaris: a Mendelian randomization study.
    Xue Y, Xia Y, Cheng D, Shi T, Mei P, Hong S.

    08/20/2024
    PPARgamma regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway.

    PPARγ regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway.
    Yuan H, Yi N, Li D, Xu C, Yin GR, Zhuang C, Wang YJ, Ni S., Free PMC Article

    08/15/2024
    PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.

    PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
    Geng Q, Xu J, Cao X, Wang Z, Jiao Y, Diao W, Wang X, Wang Z, Zhang M, Zhao L, Yang L, Deng T, Fan B, Xu Y, Jia L, Xiao C.

    06/14/2024
    PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.

    PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.
    Esmaeili M, Nasr-Esfahani MH, Shoaraye Nejati A, Safaeinejad Z, Atefi A, L Megraw T, Ghaedi K., Free PMC Article

    06/13/2024
    Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARgamma.

    Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARγ.
    Cheng WL, Chao SP, Zhao F, Cai HH, Zeng Z, Cao JL, Jin Z, Deng KQ, Hu X, Wang H, Lu Z.

    05/28/2024
    Abscisic acid signaling through LANCL2 and PPARgamma induces activation of p38MAPK resulting in dormancy of prostate cancer metastatic cells.

    Abscisic acid signaling through LANCL2 and PPARγ induces activation of p38MAPK resulting in dormancy of prostate cancer metastatic cells.
    Parajuli KR, Jung Y, Taichman RS., Free PMC Article

    04/22/2024
    Dual function of activated PPARgamma by ligands on tumor growth and immunotherapy.

    Dual function of activated PPARγ by ligands on tumor growth and immunotherapy.
    Chen M, Wang H, Cui Q, Shi J, Hou Y.

    04/18/2024
    Identification of PPARG as key gene to link coronary atherosclerosis disease and rheumatoid arthritis via microarray data analysis.

    Identification of PPARG as key gene to link coronary atherosclerosis disease and rheumatoid arthritis via microarray data analysis.
    Zhang Z, Chen Y, Fu X, Chen L, Wang J, Zheng Q, Zhang S, Zhu X., Free PMC Article

    04/12/2024
    Association of Polymorphic Variants of TCF7L2 and PPARG Genes with Metabolic Markers in Patients with Early Disorders of Carbohydrate Metabolism.

    Association of Polymorphic Variants of TCF7L2 and PPARG Genes with Metabolic Markers in Patients with Early Disorders of Carbohydrate Metabolism.
    Isakova DN, Kolomeichuk SN, Petrova YA, Lyapina MV, Troshina IA, Voronin KA, Petrov IM.

    03/31/2024
    Adipocyte-rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator-activated receptor gamma/ABCG2 in epithelial ovarian cancer.

    Adipocyte‑rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator‑activated receptor gamma/ABCG2 in epithelial ovarian cancer.
    Chen S, Liu Z, Wu H, Wang B, Ouyang Y, Liu J, Zheng X, Zhang H, Li X, Feng X, Li Y, Shen Y, Zhang H, Xiao B, Yu C, Deng W., Free PMC Article

    03/5/2024
    Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor gamma following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1beta Release.

    Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor γ following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1β Release.
    Arnett E, Wolff J, Leopold Wager CM, Simper J, Badrak JL, Ontiveros CO, Ni B, Schlesinger LS.,

    02/23/2024
    Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARgamma.

    Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ.
    Shibata T, Bhat SA, Cao D, Saito S, Bernstein EA, Nishi E, Medenilla JD, Wang ET, Chan JL, Pisarska MD, Tourtellotte WG, Giani JF, Bernstein KE, Khan Z., Free PMC Article

    02/7/2024
    PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.

    PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.
    Vetrivel S, Tamburello M, Oßwald A, Zhang R, Khan A, Jung S, Baker JE, Rainey WE, Nowak E, Altieri B, Detomas M, Watts D, Williams TA, Wielockx B, Beuschlein F, Reincke M, Sbiera S, Riester A., Free PMC Article

    12/20/2023
    Expression analysis of PPAR-related lncRNAs in breast cancer.

    Expression analysis of PPAR-related lncRNAs in breast cancer.
    Ghafouri-Fard S, Nicknam A, Safarzadeh A, Eslami S, Samsami M, Jamali E.

    11/18/2023
    Role of PPAR-related genes in chronic heart failure: evidence from large populations.

    Role of PPAR-related genes in chronic heart failure: evidence from large populations.
    Ke ZP, Tao WQ, Zhao G, Cheng K., Free PMC Article

    11/14/2023
    Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-gamma) expression in colorectal carcinoma: Relation to the available clinicopathological parameters.

    Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-γ) expression in colorectal carcinoma: Relation to the available clinicopathological parameters.
    Bedeer AE, El-Ghaffar Heabah NA.

    11/6/2023
    Perilipin 2-positive mononuclear phagocytes accumulate in the diabetic retina and promote PPARgamma-dependent vasodegeneration.

    Perilipin 2-positive mononuclear phagocytes accumulate in the diabetic retina and promote PPARγ-dependent vasodegeneration.
    Blot G, Karadayi R, Przegralek L, Sartoris TM, Charles-Messance H, Augustin S, Negrier P, Blond F, Muñiz-Ruvalcaba FP, Rivera-de la Parra D, Vignaud L, Couturier A, Sahel JA, Acar N, Jimenez-Corona A, Delarasse C, Garfias Y, Sennlaub F, Guillonneau X., Free PMC Article

    11/2/2023
    Loss of PPARgamma activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.

    Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.
    Caruso JA, Wang X, Murrow LM, Rodriguez CI, Chen-Tanyolac C, Vu L, Chen YY, Gascard P, Gartner ZJ, Kerlikowske K, Tlsty TD., Free PMC Article

    11/2/2023
    PPARgamma inhibits small airway remodeling through mediating the polarization homeostasis of alveolar macrophages in COPD.

    PPARγ inhibits small airway remodeling through mediating the polarization homeostasis of alveolar macrophages in COPD.
    He S, Tian R, Zhang X, Yao Q, Chen Q, Liu B, Liao L, Gong Y, Yang H, Wang D.

    11/2/2023
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