| Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration. | Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration.
Nazarov IB, Zilov DS, Gordeev MN, Potapenko EV, Yeremenko N, Tomilin AN., Free PMC Article | 02/12/2024 |
| Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1. | Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1.
Kamhieh-Milz J, Chen L, Goettsch C, Pfefferkorn AM, Hofmann A, Brunssen C, Müller GM, Walther T, Ashraf MI, Moll G, Morawietz H, Witowski J, Catar R. | 09/6/2023 |
| Upregulation of IL-8, osteonectin, and myonectin mRNAs by intermittent hypoxia via OCT1- and NRF2-mediated mechanisms in skeletal muscle cells. | Upregulation of IL-8, osteonectin, and myonectin mRNAs by intermittent hypoxia via OCT1- and NRF2-mediated mechanisms in skeletal muscle cells.
Takasawa S, Shobatake R, Itaya-Hironaka A, Makino M, Uchiyama T, Sakuramoto-Tsuchida S, Takeda Y, Ota H, Yamauchi A., Free PMC Article | 01/14/2023 |
| LncRNA AC026401.3 interacts with OCT1 to intensify sorafenib and lenvatinib resistance by activating E2F2 signaling in hepatocellular carcinoma. | LncRNA AC026401.3 interacts with OCT1 to intensify sorafenib and lenvatinib resistance by activating E2F2 signaling in hepatocellular carcinoma.
Wang Y, Tan K, Hu W, Hou Y, Yang G. | 10/8/2022 |
| Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities. | Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities.
Doetsch DA, Ansari S, Jensen O, Gebauer L, Dücker C, Brockmöller J, Sachkova A., Free PMC Article | 08/27/2022 |
| NPR3, transcriptionally regulated by POU2F1, inhibits osteosarcoma cell growth through blocking the PI3K/AKT pathway. | NPR3, transcriptionally regulated by POU2F1, inhibits osteosarcoma cell growth through blocking the PI3K/AKT pathway.
Li S, Guo R, Peng Z, Quan B, Hu Y, Wang Y, Wang Y. | 04/9/2022 |
| Positive feedback loop of lncRNA FAM201A/miR146a5p/POU2F1 regulates IL1betainduced chondrocyte injury in vitro. | Positive feedback loop of lncRNA FAM201A/miR‑146a‑5p/POU2F1 regulates IL‑1β‑induced chondrocyte injury in vitro.
Gan K, Wu W, Li J, Xu D, Liu Y, Bi M, Lu L, Li J., Free PMC Article | 03/12/2022 |
| Hypoxia-inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy. | Hypoxia-inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy.
Ho KH, Shih CM, Liu AJ, Chen KC., Free PMC Article | 02/12/2022 |
| OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH. | OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH.
Ogura T, Azuma K, Sato J, Kinowaki K, Takayama KI, Takeiwa T, Kawabata H, Inoue S., Free PMC Article | 12/18/2021 |
| Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress. | Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress.
Stepchenko AG, Portseva TN, Glukhov IA, Kotnova AP, Lyanova BM, Georgieva SG, Pankratova EV., Free PMC Article | 12/18/2021 |
| OBF1 and Oct factors control the germinal center transcriptional program. | OBF1 and Oct factors control the germinal center transcriptional program.
Song S, Cao C, Choukrallah MA, Tang F, Christofori G, Kohler H, Wu F, Fodor BD, Frederiksen M, Willis SN, Jackson JT, Nutt SL, Dirnhofer S, Stadler MB, Matthias P. | 12/11/2021 |
| Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer. | Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer.
Li Z, Su J, Sun M, Song J, Sun H, Fan J, Chen G, Shan C, Qi Q, Zhang S. | 09/11/2021 |
| Structural facets of POU2F1 in light of the functional annotations and sequence-structure patterns. | Structural facets of POU2F1 in light of the functional annotations and sequence-structure patterns.
Dey A, Sen S, Uversky VN, Maulik U. | 07/17/2021 |
| Novel small molecular inhibitor of Pit-Oct-Unc transcription factor 1 suppresses hepatocellular carcinoma cell proliferation. | Novel small molecular inhibitor of Pit-Oct-Unc transcription factor 1 suppresses hepatocellular carcinoma cell proliferation.
Wang Y, Liu S, Chen Q, Ren Y, Li Z, Cao S. | 06/26/2021 |
| Collective invasion of glioma cells through OCT1 signalling and interaction with reactive astrocytes after surgery. | Collective invasion of glioma cells through OCT1 signalling and interaction with reactive astrocytes after surgery.
Kim Y, Lee D, Lawler S., Free PMC Article | 05/1/2021 |
| FBXO25 Promotes Cutaneous Squamous Cell Carcinoma Growth and Metastasis through Cyclin D1. | FBXO25 Promotes Cutaneous Squamous Cell Carcinoma Growth and Metastasis through Cyclin D1.
Kuzmanov A, Johansen P, Hofbauer G. | 04/3/2021 |
| lncRNA CRNDE promotes the proliferation and metastasis by acting as sponge miR-539-5p to regulate POU2F1 expression in HCC. | lncRNA CRNDE promotes the proliferation and metastasis by acting as sponge miR-539-5p to regulate POU2F1 expression in HCC.
Li Z, Wu G, Li J, Wang Y, Ju X, Jiang W., Free PMC Article | 01/9/2021 |
| LncRNA SND1-IT1 accelerates the proliferation and migration of osteosarcoma via sponging miRNA-665 to upregulate POU2F1. | LncRNA SND1-IT1 accelerates the proliferation and migration of osteosarcoma via sponging miRNA-665 to upregulate POU2F1.
Jin XM, Xu B, Zhang Y, Liu SY, Shao J, Wu L, Tang JA, Yin T, Fan XB, Yang TY. | 12/26/2020 |
| Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1. | Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1.
Ma Y, Sekiya M, Kainoh K, Matsuda T, Iwasaki H, Osaki Y, Sugano Y, Suzuki H, Takeuchi Y, Miyamoto T, Yahagi N, Nakagawa Y, Matsuzaka T, Shimano H. | 09/5/2020 |
| Oct1 associates with the CDX2 promoter in both normal and AML primary patient samples, but recruits the histone demethylase Jmjd1a/Kdm3a to remove the repressive H3K9me2 mark only in malignant specimens. | Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia.
Jafek JL, Shakya A, Tai PY, Ibarra A, Kim H, Maddox J, Chumley J, Spangrude GJ, Miles RR, Kelley TW, Tantin D., Free PMC Article | 02/22/2020 |
| regulates castration-resistant prostate cancer-specific target genes in addition to representative androgen receptor-regulated genes such as ACSL3 | Integrative Genomic Analysis of OCT1 Reveals Coordinated Regulation of Androgen Receptor in Advanced Prostate Cancer.
Takayama KI, Suzuki Y, Yamamoto S, Obinata D, Takahashi S, Inoue S. | 12/7/2019 |
| Patients with low OCT-1 activity and high ABCB1 fold rise have poor long-term outcomes. | Patients with low OCT-1 activity and high ABCB1 fold rise have poor long-term outcomes in response to tyrosine kinase inhibitor therapy.
Eadie LN, Hughes TP, White DL. | 06/15/2019 |
| Results identify BRCA1 as an Oct1 ubiquitin ligase that catalyzes Oct1 degradation to promote oxidative metabolism and restrict tumorigenicity. | BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism.
Vázquez-Arreguín K, Maddox J, Kang J, Park D, Cano RR, Factor RE, Ludwig T, Tantin D., Free PMC Article | 02/9/2019 |
| Changes in the expression level of Oct-1A, Oct-1L, Oct-1X, and Oct-1Z isoforms and CD14 surface antigen during differentiation of HL-60 monocytic cells induced in vitro by dimethyl sulfoxide were studied, and the expression level of the four Oct-1 isoforms in vivo in human monocytes was determined. | Differentiation of Monocytic Cells Is Accompanied by a Change in the Expression of the Set of Oct-1 Isoforms.
Stepchenko AG, Lyanova BM, Krylova ID, Ilyin YV, Georgieva SG, Pankratova EV. | 01/12/2019 |
| E6/E7-p53-POU2F1-CTHRC1 axis promotes cervical cancer cell invasion and metastasis | E6/E7-P53-POU2F1-CTHRC1 axis promotes cervical cancer metastasis and activates Wnt/PCP pathway.
Zhang R, Lu H, Lyu YY, Yang XM, Zhu LY, Yang GD, Jiang PC, Re Y, Song WW, Wang JH, Zhang CC, Gu F, Luo TJ, Wu ZY, Xu CJ., Free PMC Article | 11/10/2018 |