| The Human Paraoxonase 2: An Optimized Procedure for Refolding and Stabilization Facilitates Enzyme Analyses and a Proteomics Approach. | The Human Paraoxonase 2: An Optimized Procedure for Refolding and Stabilization Facilitates Enzyme Analyses and a Proteomics Approach.
Lampitella EA, Marone M, Achanta NSK, Porzio E, Trepiccione F, Manco G., Free PMC Article | 07/8/2024 |
| Contribution of the Paraoxonase-2 Enzyme to Cancer Cell Metabolism and Phenotypes. | Contribution of the Paraoxonase-2 Enzyme to Cancer Cell Metabolism and Phenotypes.
Campagna R, Serritelli EN, Salvolini E, Schiavoni V, Cecati M, Sartini D, Pozzi V, Emanuelli M., Free PMC Article | 02/28/2024 |
| Paraoxonase-2 is upregulated in triple negative breast cancer and contributes to tumor progression and chemoresistance. | Paraoxonase-2 is upregulated in triple negative breast cancer and contributes to tumor progression and chemoresistance.
Campagna R, Pozzi V, Giorgini S, Morichetti D, Goteri G, Sartini D, Serritelli EN, Emanuelli M. | 04/19/2023 |
| Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation. | Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation.
Karlov VD, Pestov NB, Shakhparonov MI, Korneenko TV., Free PMC Article | 03/30/2023 |
| PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway. | PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway.
Ye Y, Zhang J, Guo Y, Zhu J, Tang B, Fan P., Free PMC Article | 02/28/2023 |
| Role Played by Paraoxonase-2 Enzyme in Cell Viability, Proliferation and Sensitivity to Chemotherapy of Oral Squamous Cell Carcinoma Cell Lines. | Role Played by Paraoxonase-2 Enzyme in Cell Viability, Proliferation and Sensitivity to Chemotherapy of Oral Squamous Cell Carcinoma Cell Lines.
Campagna R, Belloni A, Pozzi V, Salvucci A, Notarstefano V, Togni L, Mascitti M, Sartini D, Giorgini E, Salvolini E, Santarelli A, Lo Muzio L, Emanuelli M., Free PMC Article | 01/14/2023 |
| Association of Paraoxonase-2 (C1053G) Gene Polymorphism with the Expression of Paraoxonase-2 Gene in Patients of Ischemic Stroke - A Pilot Study in Indian Population. | Association of Paraoxonase-2 (C1053G) Gene Polymorphism with the Expression of Paraoxonase-2 Gene in Patients of Ischemic Stroke - A Pilot Study in Indian Population.
Kumari S, Singh R, Chandra S, Mehndiratta M, Debnath E, Dhamija RK. | 10/1/2022 |
| Paraoxonase 2 C311S single nucleotide polymorphism is associated with type C lesions in coronary atherosclerosis. | Paraoxonase 2 C311S single nucleotide polymorphism is associated with type C lesions in coronary atherosclerosis.
Paszek E, Godlewski J, Wołkow P, Żmudka K, Słowik A, Legutko J, Kleczyński P. | 07/9/2022 |
| Airway epithelial Paraoxonase-2 in obese asthma. | Airway epithelial Paraoxonase-2 in obese asthma.
Winnica DE, Monzon A, Ye S, Vladar EK, Saal M, Cooney R, Liu C, Sharma S, Holguin F., Free PMC Article | 04/30/2022 |
| Insights into the role of paraoxonase 2 in human pathophysiology. | Insights into the role of paraoxonase 2 in human pathophysiology.
Parween F, Gupta RD. | 04/23/2022 |
| Insights into the role of paraoxonase 2 in human pathophysiology. | Insights into the role of paraoxonase 2 in human pathophysiology.
Parween F, Gupta RD., Free PMC Article | 03/26/2022 |
| Paraoxonase 2 protects against the CML mediated mitochondrial dysfunction through modulating JNK pathway in human retinal cells. | Paraoxonase 2 protects against the CML mediated mitochondrial dysfunction through modulating JNK pathway in human retinal cells.
Ravi R, Subramaniam Rajesh B. | 01/15/2022 |
| Paraoxonase-2: A potential biomarker for skin cancer aggressiveness. | Paraoxonase-2: A potential biomarker for skin cancer aggressiveness.
Bacchetti T, Salvolini E, Pompei V, Campagna R, Molinelli E, Brisigotti V, Togni L, Lucarini G, Sartini D, Campanati A, Mattioli-Belmonte M, Rubini C, Ferretti G, Offidani A, Emanuelli M. | 12/11/2021 |
| PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis. | PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis.
Pan L, Hong C, Chan LN, Xiao G, Malvi P, Robinson ME, Geng H, Reddy ST, Lee J, Khairnar V, Cosgun KN, Xu L, Kume K, Sadras T, Wang S, Wajapeyee N, Müschen M., Free PMC Article | 07/24/2021 |
| WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2. | WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2.
Carusone TM, Cardiero G, Cerreta M, Mandrich L, Moran O, Porzio E, Catara G, Lacerra G, Manco G., Free PMC Article | 03/20/2021 |
| Effect of High Glucose-Induced Oxidative Stress on Paraoxonase 2 Expression and Activity in Caco-2 Cells. | Effect of High Glucose-Induced Oxidative Stress on Paraoxonase 2 Expression and Activity in Caco-2 Cells.
Morresi C, Cianfruglia L, Sartini D, Cecati M, Fumarola S, Emanuelli M, Armeni T, Ferretti G, Bacchetti T., Free PMC Article | 08/13/2020 |
| The rs7785846 (CT+TT) genotype carriers of PON2 gene are more susceptible to hearing impairment when exposed to high noise intensity. | [Association between PON2 gene polymorphisms and susceptibility to noise-induced hearing loss].
Wu SS, Yu JN, Jiao J, Chen GS, Zhang CY, Yu SF. | 07/11/2020 |
| it is a oncogene which promotes gastric cancer. | The clinical and prognostic significance of paraoxonase-2 in gastric cancer patients: immunohistochemical analysis.
Wang X, Xu G, Zhang J, Wang S, Ji M, Mo L, Zhu M, Li J, Zhou G, Lu J, Chen C. | 02/29/2020 |
| SOD2 A16V, but not PON2 S311C, polymorphism may be one of the genetic determinants for polycystic ovary syndrome in Chinese women | Association of SOD2 A16V and PON2 S311C polymorphisms with polycystic ovary syndrome in Chinese women.
Liu Q, Liu H, Bai H, Huang W, Zhang R, Tan J, Guan L, Fan P. | 12/28/2019 |
| PON2 decreases OC cell proliferation by inhibiting insulin like growth factor-1 expression and signaling. | Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer.
Devarajan A, Su F, Grijalva V, Yalamanchi M, Yalamanchi A, Gao F, Trost H, Nwokedi J, Farias-Eisner G, Farias-Eisner R, Fogelman AM, Reddy ST., Free PMC Article | 12/7/2019 |
| suggesting that PON2 is necessary for proper mitochondrial function | Paraoxonase 2 prevents the development of heart failure.
Li W, Kennedy D, Shao Z, Wang X, Kamdar AK, Weber M, Mislick K, Kiefer K, Morales R, Agatisa-Boyle B, Shih DM, Reddy ST, Moravec CS, Tang WHW., Free PMC Article | 08/3/2019 |
| No significant differences were observed between PON2 and PON3 gene expression in psoriatic lesional and non lesional skin compared with healthy controls | Paraoxonases and psoriasis: negative imbalance of antioxidant endogenous mechanisms.
Schiattarella M, Caiazzo G, Di Caprio R, Lembo S, Raimondo A, Ayala F, Balato N, Monfrecola G, Fortunato G, Balato A. | 06/22/2019 |
| These experiments delineate a PON2 redox-dependent mechanism that regulates endothelial cell TF activity and prevents systemic coagulation activation and inflammation. | Paraoxonase-2 regulates coagulation activation through endothelial tissue factor.
Ebert J, Wilgenbus P, Teiber JF, Jurk K, Schwierczek K, Döhrmann M, Xia N, Li H, Spiecker L, Ruf W, Horke S. | 05/25/2019 |
| Microarray analysis revealed differential expression of three vitamin D associated genes in the aortic adventitia in rheumatoid arthritis (RA) and non-RA patients with coronary artery disease: while the expression of GADD45A and NCOR1 was higher, the expression of PON2 was lower in RA patients. | Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis.
Oma I, Olstad OK, Andersen JK, Lyberg T, Molberg Ø, Fostad I, Wang Fagerland M, Almdahl SM, Rynning SE, Yndestad A, Aukrust P, Whist JE, Hollan I., Free PMC Article | 02/16/2019 |
| In donor retina from patients with diabetes, all three PON1, PON2 and PON3 were expressed, and there was a significant increase in PON3 expression compared to control. This might be the reason for the increased thiolactonase activity observed in diabetic retina compared to control | Ocular distribution of antioxidant enzyme paraoxonase & its alteration in cataractous lens & diabetic retina.
Bharathidevi SR, Babu KA, Jain N, Muthukumaran S, Umashankar V, Biswas J, Angayarkanni N., Free PMC Article | 05/5/2018 |