| Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis. | Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis.
Heinzelmann K, Hu Q, Hu Y, Dobrinskikh E, Ansari M, Melo-Narváez MC, Ulke HM, Leavitt C, Mirita C, Trudeau T, Saal ML, Rice P, Gao B, Janssen WJ, Yang IV, Schiller HB, Vladar EK, Lehmann M, Königshoff M., Free PMC Article | 09/3/2022 |
| Engineering of siRNA loaded PLGA Nano-Particles for highly efficient silencing of GPR87 gene as a target for pancreatic cancer treatment. | Engineering of siRNA loaded PLGA Nano-Particles for highly efficient silencing of GPR87 gene as a target for pancreatic cancer treatment.
Ceylan S, Bahadori F, Akbas F. | 04/13/2021 |
| the basal activity of GPR87 was investigated. | Signaling via G proteins mediates tumorigenic effects of GPR87.
Niss Arfelt K, Fares S, Sparre-Ulrich AH, Hjortø GM, Gasbjerg LS, Mølleskov-Jensen AS, Benned-Jensen T, Rosenkilde MM. | 12/2/2017 |
| we reported that GPR87 expression was significantly upregulated in pancreatic cancer, and higher GPR87 correlated with shorter overall survival of patients with pancreatic cancer. | Overexpression of G protein-coupled receptor GPR87 promotes pancreatic cancer aggressiveness and activates NF-κB signaling pathway.
Wang L, Zhou W, Zhong Y, Huo Y, Fan P, Zhan S, Xiao J, Jin X, Gou S, Yin T, Wu H, Liu T., Free PMC Article | 07/29/2017 |
| knockdown of GPR87 led to a p53-dependent signal transduction and caused apoptosis in the bladder cancer cells. | G Protein-Coupled Receptor 87 (GPR87) Promotes Cell Proliferation in Human Bladder Cancer Cells.
Zhang X, Liu D, Hayashida Y, Okazoe H, Hashimoto T, Ueda N, Sugimoto M, Kakehi Y., Free PMC Article | 07/16/2016 |
| This study aimed to clarify the role of GPR87 in urothelial carcinoma of the bladder. | Expression and role of GPR87 in urothelial carcinoma of the bladder.
Okazoe H, Zhang X, Liu D, Shibuya S, Ueda N, Sugimoto M, Kakehi Y., Free PMC Article | 10/17/2015 |
| GPR87 promotes the growth and metastasis of CD133(+) cancer stem-like cells, and our findings may reveal new targets for HCC prevention or therapy | G protein-coupled receptor 87 (GPR87) promotes the growth and metastasis of CD133⁺ cancer stem-like cells in hepatocellular carcinoma.
Yan M, Li H, Zhu M, Zhao F, Zhang L, Chen T, Jiang G, Xie H, Cui Y, Yao M, Li J., Free PMC Article | 10/26/2013 |
| GPR87 knockdown sensitized cancer cells to DNA damage-induced growth suppression via enhanced p53 stabilization and activation. | The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress.
Zhang Y, Qian Y, Lu W, Chen X., Free PMC Article | 01/21/2010 |
| Human GPR87 mRNA transcript was preferentially overexpressed in squamous cell carcinomas. Up-regulation of both, transcript and protein, was detected in samples of SCC of the lung, cervix, skin and head and neck (pharynx, larynx and epiglottis). | hGPR87 contributes to viability of human tumor cells.
Glatt S, Halbauer D, Heindl S, Wernitznig A, Kozina D, Su KC, Puri C, Garin-Chesa P, Sommergruber W. | 01/21/2010 |
| Results suggest that the GPR87 is a LPA receptor which evolved from a common ancestor of P2Y receptors. | The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor.
Tabata K, Baba K, Shiraishi A, Ito M, Fujita N. | 01/21/2010 |
| G-protein coupled receptor(GPR87) stands out as a candidate for further target validation due to its marked overexpression and correlation on a mutation-based level to squamous cell carcinoma | GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung.
Gugger M, White R, Song S, Waser B, Cescato R, Rivière P, Reubi JC., Free PMC Article | 01/21/2010 |