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    FXYD6 FXYD domain containing ion transport regulator 6 [ Homo sapiens (human) ]

    Gene ID: 53826, updated on 2-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Identification of FXYD6 as the novel biomarker for glioma based on differential expression and DNA methylation.

    Identification of FXYD6 as the novel biomarker for glioma based on differential expression and DNA methylation.
    Hou W, Cai J, Shen P, Zhang S, Xiao S, You P, Tong Y, Li K, Qi Z, Luo H., Free PMC Article

    01/5/2024
    FXYD protein isoforms differentially modulate human Na/K pump function.

    FXYD protein isoforms differentially modulate human Na/K pump function.
    Meyer DJ, Bijlani S, de Sautu M, Spontarelli K, Young VC, Gatto C, Artigas P., Free PMC Article

    09/4/2021
    FXYD6 was verified to be directly interacting with miR-137..

    MicroRNA-137 is downregulated in human osteosarcoma and regulates cell proliferation and migration through targeting FXYD6.
    Li ZM, Zhang HY, Wang YX, Wang WB.

    10/8/2016
    FXYD6 plays a critical role of in hepatocellular carcinoma disease progression.

    FXYD6: a novel therapeutic target toward hepatocellular carcinoma.
    Gao Q, Chen X, Duan H, Wang Z, Feng J, Yang D, Song L, Zhou N, Yan X., Free PMC Article

    03/7/2015
    FXYD6 gene might play an important role in schizophrenia susceptibility.

    [A family-based association study of FXYD6 gene polymorphisms and schizophrenia].
    Jiao LZ, Wang B, Niu XR, Ma XD, Li JP, Shen B, Huang YL, Zhang H, Zhang R, Ma J.

    12/10/2011
    these results support that FXYD6 is a susceptibility gene of schizophrenia.

    A novel replicated association between FXYD6 gene and schizophrenia.
    Zhong N, Zhang R, Qiu C, Yan H, Valenzuela RK, Zhang H, Kang W, Lu S, Guo T, Ma J.

    03/19/2011
    Data show that FXYD6 does not play a role in schizophrenia in the Chinese Han population.

    No association between the FXYD6 gene and schizophrenia in the Chinese Han population.
    Zhang J, Che R, Li X, Tang W, Zhao Q, Tang R, Wang Y, Zhang Z, Ji J, Yang F, Shi Y, Ji W, Zhou G, Feng G, He L, He G, Zhang J, Che R, Li X, Tang W, Zhao Q, Tang R, Wang Y, Zhang Z, Ji J, Yang F, Shi Y, Ji W, Zhou G, Feng G, He L, He G.

    08/30/2010
    Observational study and meta-analysis of gene-disease association. (HuGE Navigator)

    Failure to confirm genetic association of the FXYD6 gene with schizophrenia: the Japanese population and meta-analysis.
    Iwata Y, Yamada K, Iwayama Y, Anitha A, Thanseem I, Toyota T, Hattori E, Ohnishi T, Maekawa M, Nakamura K, Suzuki K, Matsuzaki H, Tsuchiya KJ, Suda S, Sugihara G, Takebayashi K, Yamamoto S, Iwata K, Mori N, Yoshikawa T.

    06/30/2010
    Our findings suggest that FXYD6 is unlikely to be related to the development of schizophrenia in a Japanese population.

    A genetic association study of the FXYD domain containing ion transport regulator 6 (FXYD6) gene, encoding phosphohippolin, in susceptibility to schizophrenia in a Japanese population.
    Ito Y, Nakamura Y, Takahashi N, Saito S, Aleksic B, Iwata N, Inada T, Ozaki N, Ito Y, Nakamura Y, Takahashi N, Saito S, Aleksic B, Iwata N, Inada T, Ozaki N.

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (3) articles

    No association between the FXYD6 gene and schizophrenia in the Chinese Han population.
    Zhang J, Che R, Li X, Tang W, Zhao Q, Tang R, Wang Y, Zhang Z, Ji J, Yang F, Shi Y, Ji W, Zhou G, Feng G, He L, He G, Zhang J, Che R, Li X, Tang W, Zhao Q, Tang R, Wang Y, Zhang Z, Ji J, Yang F, Shi Y, Ji W, Zhou G, Feng G, He L, He G.

    A genetic association study of the FXYD domain containing ion transport regulator 6 (FXYD6) gene, encoding phosphohippolin, in susceptibility to schizophrenia in a Japanese population.
    Ito Y, Nakamura Y, Takahashi N, Saito S, Aleksic B, Iwata N, Inada T, Ozaki N, Ito Y, Nakamura Y, Takahashi N, Saito S, Aleksic B, Iwata N, Inada T, Ozaki N.

    A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.
    Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM, Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM.

    03/13/2008
    Base-pair changes in FXYD6 or in associated promoter/control regions are likely to cause abnormal function or expression of phosphohippolin and to increase genetic susceptibility to schizophrenia.

    A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.
    Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM, Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM., Free PMC Articles: PMC1852702, PMC1852702

    01/21/2010
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